Abraham Weber
Bristol-Myers Squibb
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Publication
Featured researches published by Abraham Weber.
Journal of Medicinal Chemistry | 1989
Daniel Bouzard; P. Di Cesare; Munir Essiz; Jean-Pierre Jacquet; Philippe Remuzon; Abraham Weber; T. Oki; M. Masuyoshi
A number of 7-substituted-1-tert-butyl-6-fluoroquinolone-3-carboxylic acids and 7-substituted-1-tert-butyl-6-fluoro-1,8-naphthyridine-3-carboxylic acids have been prepared and tested for antibacterial activities. Among those the 7-aminopyrrolidinyl 20b and the 7-diazabicyclo naphthyridine 18b are the most potent compounds in vitro and in vivo. Physicochemical data and acute toxicity are also discussed. Compound 18b, BMY 40062, exhibits the most favorable overall properties, considering in vitro and in vivo microbiological activity, its low toxicity, and pharmacokinetic profile, and was selected for clinical evaluation.
Archive | 1987
Cesare Pierre Di; Jean-Pierre Jacquet; Munir Essiz; Philippe Remuzon; Daniel Bouzard; Abraham Weber
Archive | 1979
Daniel Bouzard; Abraham Weber; Jacques Stemer
Archive | 1988
Abraham Weber; Daniel Bouzard; Munir Essiz; Pierre Di Cesare; Jean-Pierre Jacquet; Philippe Remuzon
Archive | 1975
Daniel Bouzard; Abraham Weber
Archive | 1988
Abraham Weber; Daniel Bouzard; Munir Essiz; Pierre Di Cesare; Jean-Pierre Jacquet; Philippe Remuzon
Archive | 1980
Murray Arthur Kaplan; Daniel Bouzard; Claude Perol; Jacques Stemer; Abraham Weber
Archive | 1975
Daniel Bouzard; Abraham Weber
Archive | 1977
Daniel Bouzard; Abraham Weber
Archive | 1982
Daniel Bouzard; Claude Perol; Jacques Stemer; Abraham Weber; Edmund S Granatek