Adam M. Shiroff

Emergency Department Thoracotomy for Penetrating Injuries of the Heart and Great Vessels: An Appraisal of 283 Consecutive Cases From Two Urban Trauma Centers

BACKGROUND Historically, patients with penetrating cardiac injuries have enjoyed the best survival after emergency department thoracotomy (EDT), but further examination of these series reveals a preponderance of cardiac stab wound (SW) survivors with only sporadic cardiac gunshot wound (GSW) survivors. Our primary study objective was to determine which patients requiring EDT for penetrating cardiac or great vessel (CGV) injury are salvageable. METHODS All patients who underwent EDT for penetrating CGV injuries in two urban, level I trauma centers during 2000 to 2007 were retrospectively reviewed. Demographics, injury (mechanism, anatomic injury), prehospital care, and physiology (signs of life [SOL], vital signs, and cardiac rhythm) were analyzed with respect to hospital survival. RESULTS The study population (n = 283) comprised young (mean age, 27.1 years +/- 10.1 years) men (96.1%) injured by gunshot (GSW, 88.3%) or SWs (11.7%). Patients were compared by injury mechanism and number of CGV wounds with respect to survival (SW, 24.2%; GSW, 2.8%; p < 0.001; single, 9.5%; multiple, 1.4%; p = 0.003). Three predictors-injury mechanism, ED SOL, and number of CGV wounds-were then analyzed alone and in combination with respect to hospital survival. Only one patient (0.8%) with multiple CGV GSW survived EDT. CONCLUSION When the cumulative impact of penetrating injury mechanism, ED SOL, and number of CGV wounds was analyzed together, we established that those sustaining multiple CGV GSWs (regardless of ED SOL) were nearly unsalvageable. These results indicate that when multiple CGV GSWs are encountered after EDT, further resuscitative efforts may be terminated without limiting the opportunity for survival.

Necrotizing Soft Tissue Infections

Necrotising soft tissue infection (NSTI) presents unique challenges in diagnosis and management. The key to a successful outcome is a high index of suspicion in appropriate clinical settings. Type II NSTI tends to occur on an extremity in younger, healthier patients with a history of known trauma, and to be monomicrobial. Type I NSTI tends to occur on the trunk of older, less healthy patients without an obvious history of trauma, and tends to be polymicrobial. Other, rarer types exist as well. The pathophysiology of both types involves superantigen acticivty, as well as a number of microbial byproducts which collectively decrease the viscosity of pus, facilitating its spread along deep tissue planes and ultimately causing diffuse deep thrombosis and aggressive systemic sepsis. The most important physical finding is tenderness to palpation beyond the area of redness, and the lack of crepitus should not be seen as a reassuring sign. Suspected cases should undergo early surgical exploration for diagnosis, which may be performed at bedside through a small incision. Most imaging techniques are not sufficiently specific to warrant a delay in surgical exploration. The Laboratory Risk Indicator for Necrotising Fasciitis (LRINEC) shows promise as a tool for excluding suspected cases. Successful outcomes in cases of NSTI require early and aggressive serial debridement and a multidisciplinary critical care approach.

Creation of an emergency surgery service concentrates resident training in general surgical procedures.

INTRODUCTION Emergency general surgery (EGS) is increasingly being provided by academic trauma surgeons in an acute care surgery model. Our tertiary care hospital recently changed from a model where all staff surgeons (private, subspecialty academic, and trauma academic) were assigned EGS call to one in which an emergency surgery service (ESS), staffed by academic trauma faculty, cares for all EGS patients. In the previous model, many surgeries were “not covered” by residents because of work-hour restrictions, conflicting needs, or private surgeon preference. The ESS was separate from the trauma service. We hypothesize that by creating a separate ESS, residents can accumulate needed and concentrated operative experience in a well-supervised academic environment. METHODS A prospectively accrued EGS database was retrospectively queried for the 18-month period: July 2010 to June 2011. The Accreditation Council for Graduate Medical Education (ACGME) databases were queried for operative numbers for our residency program and for national resident data for 2 years before and after creating the ESS. The ACGME operative requirements were tabulated from online sources. ACGME requirements were compared with surgical cases performed. RESULTS During the 18-month period, 816 ESS operations were performed. Of these, 307 (38%) were laparoscopy. Laparoscopic cholecystectomy and appendectomy were most common (138 and 145, respectively) plus 24 additional laparoscopic surgeries. Each resident performed, on average, 34 basic laparoscopic cases during their 2-month rotation, which is 56% of their ACGME basic laparoscopic requirement. A diverse mixture of 70 other general surgical operations was recorded for the remaining 509 surgical cases, including reoperative surgery, complex laparoscopy, multispecialty procedures, and seldom-performed operations such as surgery for perforated ulcer disease. Before the ESS, the classes of 2008 and 2009 reported that only 48% and 50% of cases were performed at the main academic institution, respectively. This improved for the classes of 2010 and 2011 to 63% and 68%, respectively, after ESS creation. CONCLUSION An ESS rotation is becoming essential in large teaching hospitals by helping to fulfill ACGME requirements and by providing emergent general surgical skills an efficient and well-supervised academic environment. Movement toward concentrating EGS on a single service can enhance resident education and may decrease the need to supplement certain aspects of general surgery education with away rotations.

Evidence-Based Appendicitis: The Initial Work-up

Abstract In this article we provide an evidence-based review of appendicitis, which is one of the most challenging conditions to diagnose in patients presenting with abdominal pain. Almost all clinicians are faced with the diagnostic work-up of these patients, and missing the diagnosis can result in patient decompensation. We review the literature from the initial description of McBurneys point to the clinical presentation, as well as the most appropriate imaging testing. Additionally, we review the usefulness of specific diagnostic laboratory tests. The use of computed tomography scans has reduced negative appendectomy rates when combined with a physical examination, and assists in ruling out appendicitis. Computed tomography scans with no contrast or just rectal contrast are becoming the standard in many institutions. It is essential that when the diagnosis of abdominal pain of unclear etiology is suspected, the clinicians discussion with the patient is well documented on the patients chart.

Enhancing the tissue donor pool through donation after death in the field.

INTRODUCTION Tissue transplantation is an important adjunct to modern medical care and is used daily to save or improve patient lives. Tissue allografts include bone, tendon, corneas, heart valves and others. Increasing utilization may lead to tissue shortages, and tissue procurement organizations continue to explore ways to expand the cadaveric donor pool. Currently more than half of all deaths occur outside the acute care setting. HYPOTHESIS Many who suffer prehospital deaths might be eligible for non-organ tissue donation. METHODS A retrospective review of electronic prehospital medical records was conducted from May 1, 2008 through December 31, 2009. All prehospital deaths were included irrespective of cause. Once identified, additional medical history was obtained from prehospital, inpatient, and emergency department records. Age, medical history, and time of death were compared to exclusion criteria for four tissue procurement organizations (MTF, LifeNet, LifeCell, EyeBank). After analysis, percentages of eligible donors were calculated. RESULTS Over 50,000 prehospital records were reviewed; 432 subjects died in the field and were eligible for analysis. Ages ranged from four to 103 years of age; the average was 68.3 (SD = 20.1) years. After exclusion for age, medical conditions, and time of death, 185 unique patients (42.8%) were eligible for donation to at least one of the four tissue procurement organizations (range 11.6%-34.3%). CONCLUSIONS After prehospital death, many individuals may be eligible for tissue donation. These findings suggest that future prospective studies exploring tissue donation after prehospital death are indicated. These studies should aim to clarify eligibility criteria, create protocols and infrastructure, and explore the ethical implications of expanding tissue donation to include this population.

Should Air Medical Patients Be Transferred on Helipad or Trauma Bay

OBJECTIVE Helicopter emergency medical services (HEMS) are widely used in regional trauma care and present unique challenges in the patient handoff process. In particular, the practice of patient handoff on the landing zone versus the trauma bay does not exist in ground emergency medical services. We hypothesized that patients handed off on the landing zone versus the trauma bay would have different patient characteristics and outcomes. METHODS A retrospective review identified 305 HEMS trauma patients received at our level 1 trauma center over a 3-year period. Patients were sorted on the basis of the handoff location, (landing zone vs. trauma bay) and assessed for predictors of injury severity including the Revised Trauma Score, the Injury Severity Score, the Trauma and Injury Severity Score, and other outcomes, primarily mortality. RESULTS Of the 305 patients, 235 (77%) were handed off in the bay, and 70 (23%) were not. Regarding the characteristics of patients who were handed off in the bay, they were more likely to have hypotension (100% vs. 73%), have a lower O(2) saturation level (97.9 vs. 99.4), and a lower Glasgow Coma Scale at the scene (10.9 vs. 13.9.). When controlling for injury severity, the odds of survival for patients who were handed off in the bay were 11.06 times the odds for patients who were not handed off in the bay. CONCLUSION In this limited study, we found that HEMS did identify the sickest patients and brought them to the trauma bay. Despite their greater injury severity, the patients handed off in the bay fared better than those handed off on the landing zone.

Medical Management at the Health Care Facility

GENERAL CONSIDERATIONS Patient Arrival and Triage In the aftermath of a blast event, the arrival patterns and initial triage of patients vary. Depending on the size of the facility and its proximity to the event, its baseline capabilities, and the preparedness of the first responders, the volume of patients will range from single digits to hundreds. In the recent Boston Marathon bombings of April 15, 2013, 3 spectators were killed and 281 casualties were treated at 27 local hospitals. In a mature trauma system, first responders are best positioned to triage victims with life-threatening injuries to designated trauma centers. Given the emotional effect of a blast event and the usual proximity of trauma centers to potential targets (major cities, transportation hubs, etc), the trauma center will likely receive a significant percentage of patients who do not actually require specialized trauma care. Once victims arrive at the health care facility, the initial triage must be multidisciplinary, coordinated, and rehearsed. A combination of experienced nurses, surgeons, and emergency physicians is required for adequate triage, during which patients can be rapidly categorized into groups, depending on the severity of injuries and the resources needed. A commonly used methodology in North America is the Simple Triage and Rapid Treatment system, whereby red, yellow, green, and black tags are used to identify immediate, delayed, minimal, and deceased or expectant patients, respectively. Although initial or primary triage is a crucial part of mass casualty incident patient care, triage is an ongoing process throughout the entire event. Individual patients must be frequently reevaluated and decisions made to maintain, upgrade, or downgrade their status relative to that of other patients to ensure the most efficient patient flow through the system. This type of continuous triage and surgical or medical decisionmaking requires experience. A senior

Republication: Incidental findings on intensivist bedside ultrasonographic examinations: Why should we care?

Introduction: The primary goal of intensivist bedside ultrasonography (INBU) is the assessment of patient hemodynamic and volume status. Inevitably, INBU examinations provide views of various thoracic and abdominal structures. Despite the rapid recent increase in utilization of INBU, there are no published descriptions of incidental findings and/or their significance in this setting. Methods: Echocardiographic and vena cava examinations were performed by noncardiologist intensivists in 124 Surgical Intensive Care Unit (SICU) patients using hand-carried ultrasound. In addition, any findings that were deemed “incidental” were recorded. Information analyzed included patient demographics, time to complete INBU examination, and the nature of each incidental finding. Incidental findings were grouped into cardiac, pulmonary, and abdominal. To determine whether incidental INBU findings may have influenced subsequent diagnostic testing patterns, radiographic, and echocardiographic examinations directly relevant to the INBU findings and performed within 48 h of the INBU examination were reviewed. Results: Fifty-eight out of 124 (46.8%) patients in the study group had at least one incidental finding. There were 86 incidental findings, with 23 patients having more than one incidental finding. Forty-eight of 86 incidental findings (55.8%) were cardiac-related, 30 (34.9%) were pulmonary-related, and 8 (9.30%) were abdominal. There were significantly more diagnostic tests performed within 48 h of INBU in the incidental finding group (1.56/patient) than in the nonincidental group (1.18/patient, P< 0.04). The most common post-INBU diagnostic tests were chest radiogram (62%), formal trans-thoracic echocardiography (21%), and abdominal roentgenogram (14%). Computed tomography, formal abdominal ultrasonography, and trans-esophageal echocardiograms were performed less often. Four of 58 patients (6.9%) had a significant change in clinical management associated with the incidental INBU findings. One patient underwent percutaneous drainage of a pleural effusion; three underwent formal echocardiography, with subsequent change in medical management. Conclusions: Nearly half of all SICU patients who underwent INBU were found to have at least one incidental finding. The presence of an incidental finding may have influenced the subsequent pattern of clinical diagnostic testing. In addition, incidental findings on INBU were associated with a significant change in clinical management in nearly 7% of patients. The following core competencies are addressed in this article: Medical knowledge, Patient care, Practice based learning and improvement, Systems based practice. Republished with permission from: Stawicki SP, Shiroff AM, Hayden GE, Panebianco NL, Kirkpatrick JN, Horan AD, Gracias VH, Dean AJ. OPUS 12 Scientist 2008;2(3):11-14.

Repetitive Myocardial Infarctions Secondary to Delirium Tremens

Delirium tremens develops in a minority of patients undergoing acute alcohol withdrawal; however, that minority is vulnerable to significant morbidity and mortality. Historically, benzodiazepines are given intravenously to control withdrawal symptoms, although occasionally a more substantial medication is needed to prevent the devastating effects of delirium tremens, that is, propofol. We report a trauma patient who required propofol sedation for delirium tremens that was refractory to benzodiazepine treatment. Extubed prematurely, he suffered a non-ST segment myocardial infarction followed by an ST segment myocardial infarction requiring multiple interventions by cardiology. We hypothesize that his myocardial ischemia was secondary to an increased myocardial oxygen demand that occurred during his stress-induced catecholamine surge during the time he was undertreated for delirium tremens. This advocates for the use of propofol for refractory benzodiazepine treatment of delirium tremens and adds to the literature on the instability patients experience during withdrawal.

Study of Placing a Second Intravenous Line in Trauma

Abstract Objective. We evaluated the benefit of emergency medical services providers’ placing a second intravenous (IV) line in the prehospital trauma setting. Our hypothesis was that the placement of a second IV catheter in trauma does not result in an improvement in heart rate, blood pressure, rehospitalizaton rate, or 30-day mortality. Methods. A retrospective chart review of 320 trauma patients in a one-year period was conducted at our level I trauma center. All trauma patients who had vascular access obtained prehospitally were included. Results. Patients with two IV lines received an average of 348.4 mL more fluid (95% confidence interval [CI]: 235.6, 461.1; p < 0.0001). No change in heart rate, pulse oximetry, Glasgow Coma Scale score, systolic blood pressure, rehospitalization rate, or 30-day mortality was noted. These effects persisted for patients who were initially tachycardic (heart rate 3.92 bpm; 95% CI –3.01, 10.82; p = 0.27) or hypotensive (blood pressure 22.00 mmHg; 95% CI −4.17, 48.16; p = 0.10). Conclusions. Redundant prehospital IV lines provided no noticeable benefit in physiologic support for trauma patients. When controlling for confounding variables, no significant outcome difference was noted, even in the hypotensive patients. The traditional approach for establishment of a secondary IV line in prehospital trauma patients should not be followed in a dogmatic fashion.