Adeel Mahmood

An ethnobotanical survey of indigenous medicinal plants in Wana district south Waziristan agency, Pakistan.

ETHNOMEDICINAL RELEVANCE Medicinal plants are treasure of any region for ailment treatment. The present research work was focused to document the indigenous knowledge of unexplored area of Wana, South Waziristan Agency, Pakistan. This was the very first study, to explore the potential ethno-medicinal plants of study area. MATERIALS AND METHODS Data was collected by opting people participation involving interviews, group meetings, semi structured discussions and filling of questionnaires. RESULTS AND DISCUSSION A total 50 wild medicinal plants belonging to 30 families were collected. Medicinal plants used against the stomach disorders were 10% followed by the cold/cough (8%), hepatitis (7%), diuretic (7%), sedative/narcotic (7%), tonic (6%), asthma (5%), cardiac problems (4%), jaundice (4%) and so on. Among plant parts used for indigenous medicines, leaves were (24%) followed by the fruit (15%), root (12%), seed (11%), whole plant (9%), arial parts (8%), flower (6%), rhizome, bark and stem (4%), bulbs (2%) and pods (1%). Xanthium strumarium reported the highest use value i.e. 0.95. CONCLUSION People of Wana still rely on indigenous plants for their basic healthcare needs. Harvesting of roots and whole plants is a big threat to conservation of medicinal plants diversity.

Indigenous knowledge of medicinal plants from Leepa valley, Azad Jammu and Kashmir, Pakistan

AIM OF STUDY Ethnomedicinal studies were conducted first time in the Leepa Valley, Azad Jammu and Kashmir (AJK), Pakistan to document indigenous medicinal knowledge of most common plant species. Pakistan is diverse country by possessing a wide range of climatic and geological condition; this country also has a mammoth diversity of flora. MATERIAL AND METHODS Rapid appraisal approach, semi-structured interviewees, personal observations and field work guided by local informants having sufficient knowledge of indigenous medicinal plants were employed to acquire ethnomedicinal information. RESULTS In this study 61 medicinal plants belonging to 40 families have been reported through 705 informants (267 females, 393 males and 45 herbal specialists) from 17 sites of Leepa valley. The main sources of herbal medicines were wild herbs (64%) followed by trees (10%), wild shrubs (8%), cultivated herbs (3%), wild and cultivated herbs (3%), wild grasses (3%), climbing wild herbs (2%), prostate wild herbs (2%), spiny shrubs (2%), fungi (2%) and ferns (1%). The most repeatedly used plant parts were leaves (34%) followed by root (16%), seed (10%), shoot (9%), fruit (8%), flower (8%), bark (6%), whole plant (4%) and barriers, tubers, nuts, oil, milky latex (1%). Preparations of medicinal plants were administrated through oral and topical routs. CONCLUSION Leepa Valley is wealthy in its indigenous medicinal plants species and the allied traditional knowledge. Indigenous medicines play important role in the local healthcare system. Most of the local community prefers to use the traditional herbal preparation for against ailments. This is the first record of indigenous knowledge from this area and there is dare need for more studies to authenticate traditional plants used in herbal remedies of study area.

Indigenous knowledge of medicinal plants from Gujranwala district, Pakistan.

AIM OF STUDY This study was focused with the aim to investigate and document the indigenous medicinal knowledge and commonly used medicinal plants from Gujranwala district, Pakistan and to establish a baseline data in continuing studies aimed at more comprehensive investigations on bio-active compounds of indigenous medicinal plants. MATERIAL AND METHODS Rapid appraisal approach (RAA) was used along with the interviews, group meetings with people having knowledge about indigenous uses of medicinal plants and individual meetings with herbalists were conducted, to collect the ethnomedicinal data. RESULTS AND DISCUSSIONS About 71 species of medicinal plants belonging to 38 families have been documented through 203 informants. Most favored plant part used for indigenous medicine was leaves (38%) followed by the seed (13%), whole plant (11%), flower (9%), fruit (8%), root and bark (6%) and the main source of these medicines was wild herbs (54%) followed by the wild shrubs, wild trees (13%), cultivated herbs (10%), cultivated trees (5%), cultivated shrubs (3%) and wild grasses (2%). The herbal preparations were mainly administrated orally and topically. CONCLUSION Gujranwala district has great diversity of medicinal plants and people are aware about their medicinal values. Few plants are playing vital role in the basic health care needs of study areas; such plants should be screened for detailed pharmacological studied to explore new biological compounds.

ETHNOMEDICINAL SURVY OF PLANTS FROM DISTRICT SIALKOT, PAKISTAN

From ancient times, plants are being used in various diseases. Many of today’s drugs have been derived from plant sources. This study was conducted to record the ethnomedicinal information of highly medicinal plants of district Sialkot, Pakistan. Medicinal uses of plants were collected through questionnaire method, interviews and direct observation of plants and their actions. Data was recorded on questionnaires and plants were collected. 25 plants belonging to 17 families were recorded in this survey and 135 locals were visited, including 80 males 43 females and 12 Hakims. Medicinal information collected by this study is presented here. This study indicated that the district Sialkot has abundance of indigenous medicinal plants to cure a broad spectrum of human ailments. There is therefore, a need to preserve this treasure and to harvest these medicinal plants from the wild, train local collectors. Thus; the fundamental features of source, scientific origin and clinical value have been established to develop the future plans of isolation, purification and synthesis therapeutical effective medicinal plants of the area.

Human health risk assessment and dietary intake of organochlorine pesticides through air, soil and food crops (wheat and rice) along two tributaries of river Chenab, Pakistan

To assess the organochlorine pesticides (OCPs) contamination and their probable hazardous effects on human health; cereal crops (wheat and rice; n=28) agricultural soil (n=28) and air (n=6) samples were collected from Gujranwala division, Punjab Province, Pakistan. ∑OCPs concentration ranged between 123 and 635 pg m(-3), 31 and 365 ng g(-1) (dw), 2.72 and 36.6 ng g(-1) (dw), 0.55 and 15.2 ng g(-1) (dw) for air, soil, rice and wheat samples, respectively. DDTs were the predominant over other OCPSs detected from screened samples while the source apportionment analysis suggested the new inputs of DDTs in the study area. EDI (estimated daily intake) of ∑OCPs through rice and wheat was found 39 and 40 ng kg(-1) day(-1), respectively. Hazard ratios (HRs) on the basis 95th percentile concentrations were exceeding the integrity for most of the investigated OCP in rice and wheat. The results revealed that there is a severe risk to the human population of the study area through consumption of contaminated cereal crops.

Ethnopharmacological studies of indigenous medicinal plants of Saravan region, Baluchistan, Iran

ETHNOPHARMACOLOGICAL RELEVANCE This study was aimed to explore the indigenous knowledge of medicinal plant species of Baluch tribes in Saravan region, Baluchistan province, Iran. MATERIAL AND METHODS Rapid appraisal approach along with the semi-structured open ended questionnaire, interviews and personal observations were used to collect the indigenous medicinal information. Quantitative analysis including the informant consensus factor (ICF) and use value (UV) was performed to evaluate the valued medicinal plants. RESULTS AND DISCUSSION A total 64 medicinal plants belonging to 30 families were reported from the study area. Among families, Lamiaceae dominated over other families and leaves dominated with 31% over other plant parts used as herbal remedies. Rhazya stricta and Datura stamonium (0.35) attributed the higher UV, followed by Otostegia persica (0.33) and Teucrium polium (0.32). Results of the ICF showed that cold/flu/fever (0.71) and blood disorders (0.57) were the most common diseases of the study area. CONCLUSION The use value and informant consensus factor substantiated that the relative importance of plant species and sharing knowledge of herbal therapies between different tribal communities of this area is still rich.

Influential role of black carbon in the soil-air partitioning of polychlorinated biphenyls (PCBs) in the Indus River Basin, Pakistan.

Levels of polychlorinated biphenyls (PCBs) were assessed in surface soils and passive air samples from the Indus River Basin, and the influential role of black carbon (BC) in the soil-air partitioning process was examined. ∑26-PCBs ranged between 0.002-3.03 pg m(-3) and 0.26-1.89 ng g(-1) for passive air and soil samples, respectively. Lower chlorinated (tri- and tetra-) PCBs were abundant in both air (83.9%) and soil (92.1%) samples. Soil-air partitioning of PCBs was investigated through octanol-air partition coefficients (KOA) and black carbon-air partition coefficients (KBC-A). The results of the paired-t test revealed that both models showed statistically significant agreement between measured and predicted model values for the PCB congeners. Ratios of fBCKBC-AδOCT/fOMKOA>5 explicitly suggested the influential role of black carbon in the retention and soil-air partitioning of PCBs. Lower chlorinated PCBs were strongly adsorbed and retained by black carbon during soil-air partitioning because of their dominance at the sampling sites and planarity effect.

Occurrence of polycyclic aromatic hydrocarbons in the Soan River, Pakistan: Insights into distribution, composition, sources and ecological risk assessment

Present study investigates the occurrence, distribution and sources of ∑17 polycyclic aromatic hydrocarbons (PAHs) in the surface water of Soan River, Pakistan. The concentrations of total PAHs ranged from 61 to 207 ng/l. Low molecular weight (LMW) PAHs were recorded higher in concentrations (64.7 percent) as compared to high molecular weight (HMW) PAHs (35.6 percent). Principal component analysis (PCA) revealed domestic and industrial wastewater discharge, vehicular exhaust, petroleum residues and biomass combustion as the main sources for PAHs contamination. Using the USEPA toxic equivalency factor (TEF) approach: Benzo(a)Pyrene and Dibenzo(a,h)Anthracene contributed highly carcinogenic exposure equivalent. The surface water of the Soan River is found to be slightly polluted with PAHs thereby posing health risks to aquatic bodies.

Enrichment, geo-accumulation and risk surveillance of toxic metals for different environmental compartments from Mehmood Booti dumping site, Lahore city, Pakistan.

The present study was designed to probe the levels of heavy metals (Cd, Pb, Cr, Mn, Cu, Ni, Zn and Fe) for different environmental matrices (ground water, wastewater, sediment, soil, dust and leachates). Impact of solid waste dumping site on nearby human population has also been assessed. The results revealed that concentration of Pb, Fe, Cd, Mn and Cu surpassed the permissible limits of World Health Organization (WHO) and US Environmental Protection Agency (USEPA) in water, soil, sediments, while aforesaid metals in wastewater were above the National Environmental Quality Standards (NEQS). Our results for enrichment factor (EF) and geo-accumulation (I(geo)) values revealed that soils and sediments were contaminated with Cd, Pb, Ni and Mn. The Cd content caused a considerably high potential ecological risk (E(r)(i) ≥ 320) in soil and sediments. Pb and Cd caused high health risk (HR > 1) to local residents via dust and drinking water intake. Potential cancer risk for Pb was higher than USEPA standard values (1.0E-06-1.0E-04) through water intake. The Mehmood Booti dumping site is a potential source of toxic pollutants contamination to the surrounding population. It is recommended to take proper actions for its management to resolve this issue.

Polychlorinated biphenyls (PCBs) in air, soil, and cereal crops along the two tributaries of River Chenab, Pakistan: Concentrations, distribution, and screening level risk assessment

This study reports the first systematic data on PCB levels and their risk assessments by consumption of cereal food crops from Pakistan. Polychlorinated biphenyls (PCB) including dioxin-like PCBs (dl-PCBs) were analyzed in wheat (n=28), rice (n=28), air (n=6), and soil (n=28) samples to assess the levels, spatial distribution pattern, and their risk assessments along with the two tributaries of River Chenab, Pakistan. ∑33PCB concentrations ranged between 0.15-2.22 ng g(-1)dW, 0.05-9.21 ng g(-1)dW, 0.70-30.5 ng g(-1)dW and 41-299 pg m(-3) in the wheat, rice, soil, and air samples, respectively. In the current study, comparatively lower dioxin toxicity equivalency (TEQ) values were calculated from the previously reported data. Hazardous ratio (HR) for human health risk assessment allied to non-cancer was found lower than integrity.