Adina Hartman-Maeir

Functional disability and rehabilitation outcome in right hemisphere damaged patients with and without unilateral spatial neglect

OBJECTIVE To evaluate the impact of unilateral spatial neglect (USN) on the rehabilitation outcome and long-term functioning in activities of daily living (ADL) and instrumental ADL (IADL) of right hemisphere damaged (RHD) stroke patients. DESIGN Assessments of sensory-motor and cognitive impairment and of functional disability were conducted upon admission to rehabilitation, upon discharge from the rehabilitation hospital, and 6 months after discharge, up to a year postonset. SETTING The Loewenstein Rehabilitation Hospital, which receives patients from all general hospitals in Israel. PATIENTS Forty consecutive admissions of adult right-handed patients with a first, single, right hemispheric stroke proven by computed tomography. Based on their total score in the Behavioral Inattention Test for neglect, patients were divided into two groups: 19 with neglect (USN+) and 21 without neglect (USN-). OUTCOME MEASURES Functional Independence Measure, for ADL; The Rabideau Kitchen Evaluation, for IADL. RESULTS Impairment and disability levels of RHD patients with and without USN were clearly differentiated. Neglect is associated with lower performance on measures of impairment (sensory-motor and cognitive), as well as on measures of disability in ADL and IADL. Differences were significant in all testing periods. The recovery pattern of USN+ patients is slower and more attenuated. In both groups, most improvement occurs in the first 5 months after onset. USN is the major predictor of rehabilitation outcome from admission to follow-up. CONCLUSIONS The significance of neglect as a major source of stroke-related long-term disability justifies further research efforts to develop appropriate therapeutic modalities for this complex, multifactorial syndrome.

Activities, participation and satisfaction one-year post stroke

Purpose. To evaluate the chronic consequences of stroke in terms of activity limitations, restricted participation and dissatisfaction from life, and the relationship between these variables, in stroke survivors living in the community one-year post onset. Method. A total of 56 stroke patients (mean age: 57.7) who completed an in-patient rehabilitation programme, were evaluated one-year post onset in their homes, using the following instruments: Functional Independence Measure (FIM), Instrumental Activities of Daily Living Questionnaire (IADLq), Activity Card Sort (ACS), a work questionnaire, Life-Satisfaction Questionnaire (Li-Sat 9) and the Geriatric Depression Scale (GDS). Results. One year post stroke onset the mean FIM motor score was 75.88 (max score: 91), yet more than 50% of the sample still required assistance (usually mild to moderate) in dressing, bathing and use of stairs. The majority of the sample required full assistance in some IADL domains, notably meal preparation (77%), housekeeping (70%) and laundry (82%). Only one subject returned to paid employment and the mean activity level (ACS), representing the percentage of leisure and IADL activities retained from before stroke, was 42.8%. Satisfaction ratings were generally low but varied between domains. Only 39% were satisfied from ‘life as a whole’. The lowest satisfaction rates were noted for ‘vocational situation’ (14%), ‘leisure situation’ (34%) and ‘ability in self-care’ (43%), whereas the satisfaction rate from family life was high (84%). Significant correlations were found between overall life satisfaction scores and the overall FIM motor, IADLq, and ACS scores (Pearson r values: 0.32, 0.48 and 0.57, respectively). Activity level was found to be a significant predictor of satisfaction (p = 0.007) beyond that accounted for by demographic variables and depression. Conclusions. Stroke survivors dwelling in the community demonstrate long-standing dissatisfaction one-year post onset, correlating with activity limitation and restricted participation. The findings present a compelling need for rehabilitation services with a focus on participation in IADL and leisure activities, in order to improve the satisfaction of this population.

Participation in Occupational Performance: Reliability and Validity of the Activity Card Sort:

The Activity Card Sort (ACS) is a comprehensive instrument for assessing participation in occupational performance of instrumental, social-cultural, and leisure activities. The purpose of the study was to determine the reliability and validity of the ACS within different adult and older adult groups. The study included 263 participants comprising 5 groups of 61 healthy adults, 61 healthy older adults, 40 spouses or caregivers of individuals with Alzheimers, 45 individuals with multiple sclerosis, and 56 individuals 1 year after having a stroke. The ACS was adapted to the Israeli culture in a previous study with the authors permission. The final version that was used in this analysis included 88 picture cards of adults performing instrumental, social-cultural, and low and high physical leisure activities that the clients sort into five categories. The ACS provides a “retained activity level” score that is the percentage of activities in which a person is currently engaged divided by those with whom he or she was involved in the past. In addition, comparisons between all groups of current activity levels were analyzed. The ACS had high internal consistency (Cronbach alpha in each area) for instrumental activities of daily living (IADL) and social-cultural activities (.82, .80), and lower for low and high physical leisure activities (.66, .61). A one-way analysis of variance (ANOVA) that compared groups of participants on total retained activity level and individual activity areas showed a significant group effect on all comparisons (p<.000) that support construct validity. Post hoc Scheffe tests revealed significant differences between most groups. The same results were found for current activity level. The results support the reliability and validity of the ACS and provide a basis for its clinical use.

Unawareness and/or denial of disability: implications for occupational therapy intervention.

Occupational therapy focus on client-centred, occupational performance intervention may become complicated by the phenomena of self-awareness. The problem of awareness deficits in clients with neurological disorders may be attributed to neurological impairment of self-awareness and/or psychological denial of disability. These phenomena present themselves more commonly in combination than dichotomously and have implications for treatment outcomes. Individuals with impaired self-awareness or denial face difficulties with motivation and participation in therapy, and the adoption of compensatory strategies, which ultimately impacts on rehabilitation outcome. The extent of unawareness versus denial can be assessed by observation of a clients behavior and this information can be very useful in directing the treatment approach. The purpose of this paper is, therefore, to discuss the phenomenon of unawareness and/or denial of disability and its importance to successful rehabilitation outcomes, current thinking and research conducted in different countries. Also, detailed case examples of three clients representing three major populations of traumatic brain injury, stroke and schizophrenia who may exhibit unawareness and/or denial of disability will be presented, including intervention strategies for both phenomena.

Awareness of disabilities in stroke rehabilitation--a clinical trial

Purpose : To investigate the frequency of unawareness of disabilities after stroke during the rehabilitation stage, the relationship of unawareness with neuroanatomical variables, and the impact of unawareness on functional outcomes. Method : Sixty consecutive patients (36 with right, 24 with left hemisphere damage) admitted to rehabilitation hospital with a first, single, unilateral stroke were evaluated at admission, discharge and at 1-year post onset of stroke. Unawareness of disabilities was operationally defined as the discrepancy between therapist and patients rating on the motor scale of the functional independence measure (FIM). Functional outcomes included FIM, instrumental activities of daily living (IADL) scale, activity card sort (ACS) and safety rating scale. Results : Unawareness of disabilities was found in 44/60 patients at admission and 24/57 at discharge. There was no significant difference between the hemisphere groups in the frequency of unawareness at both times. Discharge unawareness in the right hemisphere group was significantly associated with lesions in the frontal and temporal lobes, and with lesion size. Unawareness in the left hemisphere damaged group was not associated with any neuroanatomical variables. A negative impact of unawareness at admission on functional outcomeswas not found, but it was found that unawareness at discharge was a negative predictor of activity level (ACS score) at follow up, after controlling for the severity of initial disability level. Conclusions : Unawareness of disabilities is a significant issue in stroke rehabilitation. Unawareness that persists to discharge from rehabilitation correlates with neuroanatomical variables in right hemisphere damaged patients, and is a negative predictor for some rehabilitation outcomes at follow-up.

Anosognosia for Hemiplegia in Stroke Rehabilitation

Objective: The purpose of this study was to investigate anosognosia for hemiple gia (AHP) in the rehabilitation phase after onset of stroke. Methods: Forty-six hemi plegic stroke patients, 29 with right hemisphere damage (RHD) and 17 with left hemi sphere damage (LHD) were evaluated ∼1 month after onset of stroke. Anosognosia was evaluated with an implicit measure designed to assess anosognosic behaviors (choosing between unimanual and bimanual tasks), in addition to a traditional ex plicit verbal measure. Results: AHP was found m 28% of the RHD and 24% of the LHD group. The majority of patients with AHP in the RHD group had large lesions involving the frontal, parietal, or temporal lobes and had coexisting sensory deficits and unilateral spatial neglect, whereas the LHD patients with AHP had predominantly small subcortical lesions and no sensory or attentional deficits. The functional out comes of AHP patients in both hemisphere groups revealed their inability to retain safety measures at discharge from rehabilitation (p < 0.036) and their need for assis tance in basic and instrumental activities of daily living at follow-up. Conclusions: AHP presents a significant risk for negative functional outcome in stroke rehabilita tion. The underlying mechanisms of AHP may be different for left and right hemi sphere patients, therefore requiring different intervention approaches. Key Words: Anosognosia—Cerebrovascular accident—Rehabilitation outcome.

Occupational Performance and Metacognition

This paper provides definitions of the concept of metacognition and explores its relationship to occupational performance. Metacognition is divided into two components: awareness and exec utive functions. Assessments of awareness and executive functions are reviewed, treatment guidelines for metacognitive deficits are delineated, and research findings related to clients with neurological dysfunctions are summarized. Finally, the importance of integrating metacognitive components into occupational therapy theory and practice is emphasized.

Relationships of Cognitive Performance and Daily Function of Clients following Right Hemisphere Stroke: Predictive and Ecological Validity of the LOTCA Battery:

The purpose of this study was to determine the relationship of cognitive performance, as measured by the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) battery, to daily function in patients following right hemisphere stroke. Furthermore, to explore the predictive power of cognitive performance using the LOTCA at the first rehabilitative stage after stroke to long-term functional outcomes. The method was a longitudinal research design at 3 points in time: admission to rehabilitation; discharge from the rehabilitation hospital; and at follow-up, six months after discharge, which in some cases reached one year post onset. Subjects were 40 consecutive patient admissions to a rehabilitation hospital. All patients were right-handed adults with a CT-proven, first, single, right hemispheric stroke. Based on their total cutoff score in the Behavioral Inattention Test (BIT) for unilateral spatial neglect, patients were divided into 2 subgroups: 19 with neglect and 21 without neglect. Instruments included the LOTCA, the Functional Independence Measure (FIM), the Rabideau Kitchen Evaluation and Phone use. Results showed that right hemispheric stroke patients with unilateral spatial neglect performed at a lower level than patients without neglect on all measures of cognitive skills, as well as daily functional tasks as measured by the FIM and kitchen tasks. Differences were significant in all testing periods. Relationships between cognitive and functional measures showed that visuomotor organization and thinking operations correlated at moderate to high levels in both subgroups. The predictive results from admission to follow-up suggest that unilateral spatial neglect is the major predictor of activities of daily living (ADL) and instrumental activities of daily living (IADL) task performance, however cognitive skills, especially the more complex integrated visuomotor and thinking skills, were significantly related to functional outcomes in the non-neglect group. Thus, they are crucial in the assessment of stroke patients. The predictive and ecological validity of the LOTCA battery was supported.

The Behavioural Assessment of the Dysexecutive Syndrome (BADS) in schizophrenia and its relation to functional outcomes

The purpose of this study was to establish further the validity of the Behavioural Assessment of the Dysexecutive Syndrome (BADS) in a population with schizophrenia. Specific objectives were: to examine the construct validity and sensitivity of the BADS in differentiating between adult inpatients during an acute episode of illness, adult outpatients in the chronic stages of illness, and healthy controls; and to examine the predictive validity of the BADS regarding functional outcomes within the chronic group. Participants were 30 inpatients during an acute episode of their illness; 31 outpatients in the chronic stage; and 93 healthy controls. Instruments included the BADS, the Neurobehavioral Cognitive Status Examination (Cognistat) and the Routine Task Inventory (RTI). Significant differences in BADS scores were found between participants with schizophrenia and healthy controls, and between both groups of patients, showing the chronic group to have more deficits in executive functions. In addition, within the chronic group the BADS was found to be a significant predictor of two of the RTI outcome areas, instrumental activities of daily living (IADL) and communication, beyond that accounted for by basic cognitive skills. These results support the validity of the BADS within the schizophrenic population, and highlight the importance of measuring executive functions for rehabilitation

Validity of the Executive Function Performance Test in Individuals with Schizophrenia

The purpose of this study was to examine the reliability and validity of the Executive Function Performance Test (EFPT) in a schizophrenic population. Participants were 30 individuals with the acute phase of schizophrenia and 31 with the chronic stage. Internal consistency using Cronbachs alpha was high (α = .88). Two-way multiple analysis of covariance revealed that the acute group scored significantly higher than the chronic group on almost all tasks and components of the EFPT (p = .045 to .000), supporting construct validity. Moderate to high Spearman correlation coefficients were found between the total EFPT score and the total Behavioral Assessment of the Dysexecutive Syndrome profile and standardized scores within each of the groups (r =.433 to .764; p < .017 to .000), supporting criterion validity. The findings support the use of the EFPT for identifying executive functions in the context of everyday life and instrumental activities of daily living tasks. However, further studies are needed in different populations and cultures.