Adriana C. Panayi

Gene Therapy in Skeletal Muscle Repair and Regeneration

Gene therapy (GT), or the altering of genetic material within cells to modify protein structure and quantity, is an emerging field in skeletal muscle regeneration (SMR) and maintenance [1–6]. GT techniques are acquiring increasingly significant functions in approaching various surgical problems [7, 8]. A key insight necessary for maximizing the value from the great deal already known on the regulation of SMR is that every regulatory product is potentially amenable to targeting through multiple GT techniques. This chapter will focus on current GT techniques used in muscle discussing, in particular, potential benefits for Plastic and Reconstructive Surgery (PRS).

Complications in breast augmentation with textured versus smooth breast implants: a systematic review protocol

Introduction Breast augmentation is one of the most popular aesthetic plastic surgeries worldwide. There are various types of breast implants, and these can be categorised into different broad groups based on their content, shape or surface, to name a few. When looking at the surface of the shell, they can be categorised into two main kinds: textured and smooth implants. To our knowledge, a literature review and meta-analysis of the complications of these two types of implants when used for aesthetic breast augmentation has yet to be written. Methods and analysis The PubMed, EMBASE and Cochrane electronic databases will be searched from their inception to 1 October 2017. Only cohort studies, case series, case–control studies and randomised controlled trials will be included. Identification of the articles for inclusion will be carried out by two independent researchers, and data will be extracted from these studies for analysis. This protocol defines the inclusion and exclusion criteria, as well as the primary and secondary outcomes. Statistical data analysis will be conducted in Review Manager V.5.3 from Cochrane Collaboration. The methodological quality of the included studies will also be assessed. Ethics and dissemination This review will analyse secondary data collected from studies which are not linked to any specific individual. Once completed, the conclusions of the review could prove to be a valuable resource for plastic surgeons to conduct aesthetic implant procedures. The review will be submitted for publication in a peer-reviewed journal and presented at various national and international conferences. PROSPERO registration number CRD42017078727.

Opinions on the Treatment Strategy After Breast Augmentation by Polyacrylamide Hydrogel Injection

Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of