Ágnes Melinda Kovács

Cognitive gains in 7-month-old bilingual infants.

Children exposed to bilingual input typically learn 2 languages without obvious difficulties. However, it is unclear how preverbal infants cope with the inconsistent input and how bilingualism affects early development. In 3 eye-tracking studies we show that 7-month-old infants, raised with 2 languages from birth, display improved cognitive control abilities compared with matched monolinguals. Whereas both monolinguals and bilinguals learned to respond to a speech or visual cue to anticipate a reward on one side of a screen, only bilinguals succeeded in redirecting their anticipatory looks when the cue began signaling the reward on the opposite side. Bilingual infants rapidly suppressed their looks to the first location and learned the new response. These findings show that processing representations from 2 languages leads to a domain-general enhancement of the cognitive control system well before the onset of speech.

Flexible Learning of Multiple Speech Structures in Bilingual Infants

Young and Flexible How an infant learns to understand and speak a language remains a deep scientific mystery even though millions of kids accomplish these feats each year. Furthermore, this learning capacity is apparently not even taxed to its utmost; children who grow up in bilingual families learn two languages just as rapidly as those who learn only one. Kovács and Mehler (p. 611, published online 9 July) have assessed the cognitive flexibility of preverbal 1-year-old children raised in monolingual versus bilingual households and find that the bilingual group displays an impressive facility in handling inconsistent, language-like, inputs. That is, the kids exposed to two distinct languages since birth were able to associate two distinct syllabic structures—AAB and ABA—with looking leftward and rightward, whereas the monolinguals could only do so only with the simpler AAB structure. Exposure to two languages facilitates the development of a more flexible associative learning capacity. Children acquire their native language according to a well-defined time frame. Surprisingly, although children raised in bilingual environments have to learn roughly twice as much about language as their monolingual peers, the speed of acquisition is comparable in monolinguals and bilinguals. Here, we show that preverbal 12-month-old bilingual infants have become more flexible at learning speech structures than monolinguals. When given the opportunity to simultaneously learn two different regularities, bilingual infants learned both, whereas monolinguals learned only one of them. Hence, bilinguals may acquire two languages in the time in which monolinguals acquire one because they quickly become more flexible learners.

Are all beliefs equal? Implicit belief attributions recruiting core brain regions of theory of mind.

Humans possess efficient mechanisms to behave adaptively in social contexts. They ascribe goals and beliefs to others and use these for behavioural predictions. Researchers argued for two separate mental attribution systems: an implicit and automatic one involved in online interactions, and an explicit one mainly used in offline deliberations. However, the underlying mechanisms of these systems and the types of beliefs represented in the implicit system are still unclear. Using neuroimaging methods, we show that the right temporo-parietal junction and the medial prefrontal cortex, brain regions consistently found to be involved in explicit mental state reasoning, are also recruited by spontaneous belief tracking. While the medial prefrontal cortex was more active when both the participant and another agent believed an object to be at a specific location, the right temporo-parietal junction was selectively activated during tracking the false beliefs of another agent about the presence, but not the absence of objects. While humans can explicitly attribute to a conspecific any possible belief they themselves can entertain, implicit belief tracking seems to be restricted to beliefs with specific contents, a content selectivity that may reflect a crucial functional characteristic and signature property of implicit belief attribution.

When do humans spontaneously adopt another's visuospatial perspective?

Perspective-taking is a key component of social interactions. However, there is an ongoing controversy about whether, when and how instances of spontaneous visuospatial perspective-taking occur. The aim of this study was to investigate the underlying factors as well as boundary conditions that characterize the spontaneous adoption of another persons visuospatial perspective (VSP) during social interactions. We used a novel paradigm, in which a participant and a confederate performed a simple stimulus-response (SR) compatibility task sitting at a 90° angle to each other. In this set-up, participants would show a spatial compatibility effect only if they adopted the confederates VSP. In a series of 5 experiments we found that participants reliably adopted the VSP of the confederate, as long as he was perceived as an intentionally acting agent. Our results therefore show that humans are able to spontaneously adopt the differing VSP of another agent and that there is a tight link between perspective-taking and performing actions together. The results suggest that spontaneous VSP-taking can effectively facilitate and speed up spatial alignment processes accruing from dynamic interactions in multiagent environments.

Role of the receptor Mas in macrophage-mediated inflammation in vivo

Significance The alternative renin–angiotensin system pathway, the angiotensin (Ang)-(1–7)/Mas axis, may counterbalance Ang II-mediated proinflammatory effects. To investigate the role of the Ang-(1–7)/Mas axis in immune cell function and inflammatory diseases in vivo, we used two different chronic inflammatory animal models. Deletion of Mas affects macrophage function and phenotype independently of the underlying phagocyte stimulus and aggravates the clinical course of experimental autoimmune encephalomyelitis as well as atherosclerosis in mice by tipping the in vivo balance from M(IL-4+IL-13)- to M(LPS+IFNγ)-like macrophages. Thus, modulation of the Ang-(1–7)/Mas axis counteracts the proinflammatory role of Ang II by regulating the delicate equilibrium between M(LPS+IFNγ)- and M(IL-4+IL-13)-like macrophages, thereby representing a promising pharmacological target for chronic inflammatory diseases. Recently, an alternative renin–angiotensin system pathway has been described, which involves binding of angiotensin-(1–7) to its receptor Mas. The Mas axis may counterbalance angiotensin-II–mediated proinflammatory effects, likely by affecting macrophage function. Here we investigate the role of Mas in murine models of autoimmune neuroinflammation and atherosclerosis, which both involve macrophage-driven pathomechanisms. Mas signaling affected macrophage polarization, migration, and macrophage-mediated T-cell activation. Mas deficiency exacerbated the course of experimental autoimmune encephalomyelitis and increased macrophage infiltration as well as proinflammatory gene expression in the spleen and spinal cord. Furthermore, Mas deficiency promoted atherosclerosis by affecting macrophage infiltration and migration and led to increased oxidative stress as well as impaired endothelial function in ApoE-deficient mice. In summary, we identified the Mas axis as an important factor in macrophage function during inflammation of the central nervous and vascular system in vivo. Modulating the Mas axis may constitute an interesting therapeutic target in multiple sclerosis and/or atherosclerosis.

Out of your sight, out of my mind: Knowledge about another person’s visual access modulates spontaneous visuospatial perspective-taking.

Accumulating evidence suggests that humans spontaneously adopt each other’s visuospatial perspective (VSP), but many aspects about the underlying mechanisms remain unknown. The aim of this study was to investigate whether knowledge about another’s visual access systematically modulates spontaneous VSP-taking. In a spatial compatibility task, a participant and a confederate sat at a 90°angle to each other, with visual stimuli being aligned vertically for the participants and horizontally for the confederate. In this task, VSP-taking is reflected in a spatial compatibility effect in the participant, because stimulus–response compatibility occurs only if the participant takes the confederate’s perspective. We manipulated the visual access of the confederate during the task by means of glasses with adjustable shutters that allowed or prevented the confederate from seeing the visual stimuli. The results of 2 experiments showed that people only adopted their task partner’s VSP if that person had unhindered visual access to the stimuli. Provided that the confederate had visual access to the participant’s stimuli, VSP-taking occurred regardless of whether the confederate performed the same visual task as the participant (Experiment 1) or a different, auditory task (Experiment 2). The results suggest that knowledge about another’s visual access is pivotal for triggering spontaneous VSP-taking, whereas having the same task is not. We discuss the possibility that spontaneous VSP-taking can effectively facilitate spatial alignment processes in social interaction.

Beyond Language: Childhood Bilingualism Enhances High-Level Cognitive Functions

Children growing up in a bilingual environment have to build up two language systems from the linguistic input. They will use the two languages alternately as a function of their interlocutor in their everyday interaction. At a young age, a bilingual child may be faced with somewhat different requirements than a monolingual one. This chapter will discuss the possible changes that bilingualism might induce in the cognitive system in this early phase of development.Adult neuroimaging evidence suggests that bilingualism can result in differential functional specialization of the two languages depending on the age of acquisition, and moreover, can even lead to reorganization at neuronal level. Here we present behavioral studies indicating that bilingual children outperform their monolingual peers on tasks that require high levels of cognitive control, such as executive function and false-belief tasks. The extensive experience bilingual children gain in inhibiting one language while switching to the other may lead to an enhancement of their domain-general executive control abilities that are involved in different aspects of cognitive functioning.

Cognitive adaptations induced by a multi-language input in early development.

Children around the world successfully adapt to the specific requirements of their physical and social environment, and they readily acquire any language they are exposed to. Still, learning simultaneously two languages has been a continuous concern of parents, educators and scientists. While the focus has shifted from the possible costs to the possible advantages of bilingualism, the worries still linger that early bilingualism may cause delays and confusion. Here we adopt a less dichotomist view, by asking what specific adaptations might result from simultaneously learning two languages. We will discuss findings that point to a surprising plasticity of the cognitive system allowing young infants to cope with the bilingual input and reaching linguistic milestones at the same time as monolinguals.

Reading Your Mind While You Are Reading—Evidence for Spontaneous Visuospatial Perspective Taking During a Semantic Categorization Task:

Recent studies have demonstrated people’s propensity to adopt others’ visuospatial perspectives (VSPs) in a shared physical context. The present study investigated whether spontaneous VSP taking occurs in mental space where another person’s perspective matters for mental activities rather than physical actions. Participants sat at a 90° angle to a confederate and performed a semantic categorization task on written words. From the participants’ point of view, words were always displayed vertically, while for the confederate, these words appeared either the right way up or upside down, depending on the confederate’s sitting position. Participants took longer to categorize words that were upside down for the confederate, suggesting that they adopted the confederate’s VSP without being prompted to do so. Importantly, the effect disappeared if the other’s visual access was impeded by opaque goggles. This demonstrates that human adults show a spontaneous sensitivity to others’ VSP in the context of mental activities, such as joint reading.

Retrospective attribution of false beliefs in 3-year-old children

Significance The continuous flow of social interactions requires humans to monitor others’ mental states dynamically, yet this aspect of mind reading remains largely neglected. We tested whether, beyond prospective belief tracking, young children would also attribute beliefs to others retrospectively. We found that 3-year-old children retrospectively inferred the content of someone’s beliefs by combining present information with relevant events retrieved from episodic memory. This finding shows that emerging capacities for episodic memory contribute to the development of social cognitive processes, enriching children’s ability to monitor others’ mental states. A current debate in psychology and cognitive science concerns the nature of young children’s ability to attribute and track others’ beliefs. Beliefs can be attributed in at least two different ways: prospectively, during the observation of belief-inducing situations, and in a retrospective manner, based on episodic retrieval of the details of the events that brought about the beliefs. We developed a task in which only retrospective attribution, but not prospective belief tracking, would allow children to correctly infer that someone had a false belief. Eighteen- and 36-month-old children observed a displacement event, which was witnessed by a person wearing sunglasses (Experiment 1). Having later discovered that the sunglasses were opaque, 36-month-olds correctly inferred that the person must have formed a false belief about the location of the objects and used this inference in resolving her referential expressions. They successfully performed retrospective revision in the opposite direction as well, correcting a mistakenly attributed false belief when this was necessary (Experiment 3). Thus, children can compute beliefs retrospectively, based on episodic memories, well before they pass explicit false-belief tasks. Eighteen-month-olds failed in such a task, suggesting that they cannot retrospectively attribute beliefs or revise their initial belief attributions. However, an additional experiment provided evidence for prospective tracking of false beliefs in 18-month-olds (Experiment 2). Beyond identifying two different modes for tracking and updating others’ mental states early in development, these results also provide clear evidence of episodic memory retrieval in young children.