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Dive into the research topics where Ahmed S. Yassin is active.

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Featured researches published by Ahmed S. Yassin.


Oxford Medical Case Reports | 2018

Three vessel coronary artery-left ventricular multiple micro-fistulas: a rare angiographic finding

Hossam Abubakar; Ahmed S. Ahmed; Omeralfaroug Adam; Ahmed S. Yassin

Abstract A 54-year-old woman presents with a long history exertional chest pain and was found to have left ventricular systolic dysfunction on trans-thoracic echocardiogram. Coronary angiography revealed no evidence of atherosclerotic coronary artery disease and showed multiple micro-fistulae draining from all three major coronary arteries to the left ventricle. This rare abnormality is the result of failure of obliteration of intra-trabecular embryonic sinusoids and may cause myocardial ischemia through the coronary steal mechanism.


Journal of investigative medicine high impact case reports | 2018

Thrombus in the Right Coronary Sinus of Valsalva Originating From the Left Atrial Appendage Causing Embolic Inferior Wall Myocardial Infarction

Hossam Abubakar; Ahmed S. Ahmed; Ahmed Subahi; Ahmed S. Yassin

Acute myocardial infarction (MI) is commonly a result of coronary atherosclerotic plaque rupture and superimposed thrombus formation. Nevertheless, uncommon causes of MI including embolism from aortic root and ascending aorta mural thrombi must be considered when coronary atherosclerotic disease is not evident. We report a case of a 84-year-old woman who presented with an inferior ST-segment elevation MI. Initial attempts to engage the right coronary artery (RCA) were unsuccessful. Aortic angiography revealed evidence of the left coronary artery ostium with absence of the right coronary ostium or RCA. Probing with a coronary wire where the RCA ostium was presumed to be located yielded resolution of the ST-segment elevation. The RCA was then easily engaged using a guide catheter, and angiographic evaluation showed a smooth vessel with no evidence of coronary artery disease except for abrupt termination of the distal PL2 branch. Contrast-enhanced computed tomography revealed an aortic root thrombus extending into the right coronary sinus of Valsalva and a thrombus in the left atrial appendage. The case reveals RCA embolism from an aortic root thrombus likely originating from the left trial appendage. A conservative approach to treatment with anticoagulation was pursued that resulted in full recovery. A review of the literature revealed that the etiology of aortic root thrombi is proposed to be multifactorial. Prospective randomized studies are needed to demonstrate the best treatment approach, although this appears to be impracticable given the rarity of the disease.


International Journal of Cardiology | 2018

Clinical impact of advanced chronic kidney disease on outcomes and in-hospital complications of Takotsubo Syndrome (broken-heart-syndrome): Propensity-matched national study

Ahmed S. Yassin; Oluwole Adegbala; Ahmed Subahi; Hossam Abubakar; Emmanuel Akintoye; Mohamed Abdelrahamn; Abdelrahman Ahmed; Anika Agarwal; Mohamed Shokr; Mohit Pahuja; Mahir Elder; Amir Kaki; Theodore Schreiber; Tamam Mohamad

Multiple studies evaluated the outcomes and complications rate of Takotsubo Syndrome (TTS) in patients with and without advanced chronic kidney disease (CKD), revealed conflicting results. This study aims to assess the clinical outcomes and impact of advanced CKD on patients hospitalized with Takotsubo Syndrome. Patients who presented with Takotsubo cardiomyopathy between 2010 and 2014 were identified in the National Inpatient Sample (NIS) database using the International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM), and subsequently were divided into two groups, with advanced CKD and without advanced CKD. NIS is the largest all-payer inpatient stays database in the United States. The primary outcome was the effect of advanced CKD on inpatient mortality in comparison to the non-advanced CKD group. Secondary outcomes were the impact of CKD on TTS in-hospital complications. We also evaluated the length of hospital stay and the cost of hospitalization. Propensity score-matched analysis was performed to address potential confounding. The advanced CKD group had no significant increase in the risk of In-hospital mortality (OR 0.99; 95% CI 0.75-1.31, Pu202f=u202f0.269). However, advanced CKD patients were more likely to develop acute kidney injury (AKI) requiring dialysis (OR: 5.12, 95% CI: 3.16-8.30, Pu202f=u202f<0.0001), and were more likely to stay longer at the hospital (OR 1.12; 95% CI 1.03 to 1.22, P 0.010). In conclusion, advanced chronic kidney disease does not increase immediate in-hospital mortality, neither most of the TTS in-hospital complications, apart from AKI and hospital length of stay, in comparison to the patients with non-advanced CKD.


Clinical Cardiology | 2018

Impact of Atrial Fibrillation on patients hospitalized for Acute Myocarditis: Insights from a nationally-representative United States cohort

Ahmed Subahi; Emmanuel Akintoye; Ahmed S. Yassin; Hossam Abubakar; Oluwole Adegbala; Tushar Mishra; Mohamed Abdelrahman; Mohamed Shokr; Luis Afonso

Atrial fibrillation (AF) is associated with increased all‐cause mortality in the general population. However, the impact of AF on the in‐hospital outcomes of acute myocarditis (AM) patients is not well characterized.


Case reports in cardiology | 2018

Sick Sinus Syndrome and Takotsubo Cardiomyopathy

Ahmed S. Yassin; Ahmed Subahi; Hossam Abubakar; Ahmed Rashed; Mohamed Shokr

Background. Takotsubo cardiomyopathy is associated with increased risk of ventricular arrhythmias, atrial fibrillation, and bradyarrhythmias. However, sinus node dysfunction is relatively infrequent in the setting of takotsubo cardiomyopathy. Case Report. We are reporting a case of a 73-year-old woman with a history of asymptomatic sinus bradycardia who developed sick sinus syndrome complicated by takotsubo cardiomyopathy. Conclusion. Acute symptomatic sick sinus syndrome in patients with preexisting silent sinus node dysfunction can trigger takotsubo cardiomyopathy. Understanding precipitating factors of takotsubo cardiomyopathy and identifying the patients at risk of life-threatening arrhythmia can help in refining risk stratification and therapy planning. Patients with sick sinus syndrome complicated by takotsubo cardiomyopathy may benefit from pacemaker implantation. However, evaluation on a case-by-case basis is mandatory.


Cardiovascular Revascularization Medicine | 2018

Impact and outcomes of patients with congestive heart failure complicating non-ST-segment elevation myocardial infarction, results from a nationally-representative United States cohort

Ahmed Subahi; Abdullah Abdullah; Ahmed S. Yassin; Hossam Abubakar; Ashraf Abugroun; George Eigbire; Amr Salama; Abdul Wahab; Ayman Abulawi; Eyas Kanaan; Aamer Javed; Mahir Elder; Amir Kaki; Richard Alweis; Tamam Mohamad

INTRODUCTIONnCongestive heart failure (CHF) is seen in up to 13-25% of patients with NSTEMI. Recent data describing the impact of congestive heart failure (CHF) on in-hospital outcomes in patients with non-ST-segment elevation myocardial infarction (NSTEMI) in the United States is limited. We sought to examine the in-hospital outcomes, and management of CHF in patients admitted to the hospital with NSTEMI.nnnMETHODSnNational Inpatient Sample (NIS) database (2010-2014) was analyzed to identify patients with NSTEMI using ICD-9-CM codes. The primary outcome was in-hospital mortality. Propensity score-matching analysis compared mortality in CHF patients to matched controls without CHF.nnnRESULTSnOf 247,624 patients with NSTEMI, 84,115 (34%) had CHF. Patients with CHF were less likely to receive percutaneous coronary intervention (PCI) [20.48% vs. 40.9%, Pu202f<u202f0.001] or coronary artery bypass grafting (CABG) [8.2% vs 9.6%, Pu202f<u202f0.001] during hospitalization. Also, they had longer lengths of stay and higher risk for in-hospital adverse outcomes. CHF was the strongest predictor of in-hospital death. The increased mortality risk was persistent after propensity matching (RR 1.27; 95% CI 1.22 to 1.33).nnnCONCLUSIONnCHF among patients with NSTEMI is associated with increased risk for in-hospital mortality and adverse outcomes.


American Journal of Cardiology | 2018

Financial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database)

Hossam Abubakar; Ahmed S. Yassin; Emmanuel Akintoye; Khalid Bakhit; Mohit Pahuja; Mohamed Shokr; Randy Lieberman; Luis Afonso

The objective of this study was to evaluate the financial implications and the impact of pre-existing atrial fibrillation (AF) on in-hospital outcomes in patients who underwent transcatheter aortic valve implantation (TAVI) using the Nationwide Inpatient Sample (NIS) database. We identified patients who underwent TAVI from 2011 to 2014. The primary end point was the effect of pre-existing AF on in-hospital mortality. Secondary end points included periprocedural cardiac complications, stroke, and hemorrhage requiring transfusion. We also assessed length of stay (LOS) and cost of hospitalization. A mixed-effect logistic model was used for clinical end points, and a linear mixed model was used for cost and LOS. In 6,778 patients who underwent TAVI (46.1% women and 81.4u2009±u20098.5 years old), the incidence of AF was 43.3%. After adjusting for patient- and hospital-level characteristics, pre-existing AF was not found to influence in-hospital mortality (odds ratio 1.05, 95% confidence interval 0.80 to 1.36). AF was associated with an increased risk of periprocedural cardiac complications (odds ratio 1.46, 95% confidence interval 1.22 to 1.75), longer LOS (pu2009<0.001) and an increased cost of hospitalization (US


American Journal of Cardiology | 2018

Outcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation

Ahmed S. Yassin; Ahmed Subahi; Hossam Abubakar; Emmanuel Akintoye; Rashid Alhusain; Oluwole Adegbala; Abdelrahman Ahmed; Adel Elmoughrabi; Eihab Subahi; Mohit Pahuja; Ali Sahlieh; Mahir Elder; Amir Kaki; Theodore Schreiber; Tamam Mohamad

51,852 vs US


American Journal of Cardiology | 2018

Comparison of Hospital Outcomes of Transcatheter AorticValve Implantation With Versus Without Hypothyroidism

Ahmed Subahi; Ahmed S. Yassin; Oluwole Adegbala; Emmanuel Akintoye; Hossam Abubakar; Adel Elmoghrabi; Walid Ibrahim; Mustafa Ajam; Mohit Pahuja; Jarrett Weinberger; Diane Levine; Luis Afonso

49,599). In conclusion, pre-existing AF did not impact in-hospital mortality in TAVI patients but was associated with increased cardiac complications, a longer hospital LOS, and a higher cost of hospitalization.


Case reports in cardiology | 2017

AngioVac System Used for Vegetation Debulking in a Patient with Tricuspid Valve Endocarditis: A Case Report and Review of the Literature

Hossam Abubakar; Ahmed Rashed; Ahmed Subahi; Ahmed S. Yassin; Mohamed Shokr; Mahir Elder

Comparative outcomes of transcatheter aortic valve implantation (TAVI) in patients with and without liver cirrhosis are scarce. This study aimed to assess the clinical outcomes and impact of liver cirrhosis on patients who underwent TAVI. Patient with liver cirrhosis who underwent TAVI 2011 to 2014 were identified in the National Inpatient Sample database using the International Classification of Diseases, ninth revision, Clinical Modification (ICD-9-CM). The primary outcome was the effect of liver cirrhosis on inpatient mortality. Secondary outcomes were the impact of liver cirrhosis on post-TAVI complications. We also evaluated the length of hospital stay and the cost of hospitalization. Propensity score-matched analysis was performed to address potential confounding. The cirrhotic patients who underwent TAVI had no significant increase in the risk of in-hospital mortality (odds ratio [OR] 1.12, 95% confidence interval [CI] 0.59 to 2.10, p = 0.734) or after procedural complications. Furthermore, cirrhotic patients were less likely to develop vascular complications requiring surgery (OR 0.47, 95% CI 0.23 to 0.98, p = 0.043), to develop after procedural deep vein thrombosis(OR <0.00, 95% CI <0.001 to <0.0001, p <0.0001), and to require pacemaker implantation. However, cirrhotic patients were more likely to undergo nonroutine hospital discharges (OR 1.50, 95% CI 1.15 to 1.96, p = 0.003). In conclusion, TAVI is a safe and reasonable therapeutic option for cirrhotic patients with severe aortic stenosis, requiring aortic valve replacement.

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Amir Kaki

Wayne State University

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Mahir Elder

Wayne State University

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Oluwole Adegbala

Englewood Hospital and Medical Center

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