Ahmet R. Aslan

Resolution of Diurnal Incontinence and Nocturnal Enuresis After Adenotonsillectomy in Children

PURPOSE Adenotonsillar hyperplasia causes upper airway obstruction, leading to obstructive sleep apnea. We reviewed the incidence of nocturnal enuresis in a population of children with adenotonsillar hyperplasia. In addition, we investigated the rate of resolution or improvement in enuresis following surgery for relief of adenotonsillar hyperplasia. MATERIALS AND METHODS We studied 86 consecutive prepubertal children, 46 boys and 40 girls, who underwent adenotonsillectomy. Severity of adenotonsillar obstruction was graded on a scale of 1 to 4. A questionnaire regarding voiding problems, including nocturnal enuresis, voids per day and daytime enuresis episodes, was filled out preoperatively and postoperatively by the patients and their parents. RESULTS Among the 86 patients who underwent adenotonsillectomy 36 (42%) had nocturnal enuresis. In patients with nocturnal enuresis the number of episodes was significantly less after adenotonsillectomy. Overall, 12 patients (33%) had complete resolution, 11 (31%) had significant improvement and 13 (36%) showed no change. In addition, we noted a significant decrease in daytime enuresis episodes and voids per day. CONCLUSIONS Children with upper airway obstruction have a high rate of nocturnal enuresis that improves at twice the anticipated rate after treatment of the airway obstruction. In addition, we observed that daytime voiding dysfunction improves in these patients.

Apoptosis and proliferation in human undescended testes

To study apoptosis and proliferation in the testes of children with undescended testes; the degree to which undescended testes contributes to a patients ultimate fertility is debatable, but undescended testes have fewer germ cells, and some have proposed that apoptosis is an important cause.

Post-Prostatic Massage Examination for Prediction of Asymptomatic Prostatitis in Needle Biopsies: A Prospective Study

PURPOSE Although asymptomatic prostatitis is the most common noncancer diagnosis as demonstrated histologically by biopsies, screening and identification before biopsy remain unclear. In this study we prospectively evaluate the efficacy of examination of post-prostatic massage urine for prediction of asymptomatic prostatitis in biopsies. MATERIALS AND METHODS A total of 161 consecutive men 50 to 80 years old with serum prostate specific antigen 4.1 to 10.0 ng/ml, normal digital rectal examination, no evidence of clinical prostatitis or urinary tract infection, who underwent 8 or 10-core prostate biopsies under transrectal ultrasonography guidance were included in the study. Immediate pre-biopsy leukocyte count in post-prostatic massage urine was determined per high power field (400 x). We selected 5, 7 and 10 leukocytes per high power field as cutoffs, and urine was examined for prediction of histological prostatitis. RESULTS Histological diagnosis was prostatitis, benign prostatic hyperplasia and prostate cancer in 66 (41.0%), 63 (39.1%) and 32 (19.9%) patients, respectively. The mean number of leukocytes and percentage of positive post-prostatic massage urine microscopy for all cutoffs were significantly higher in subjects with prostatitis than in those without prostatitis (p <0.0001). Histological prostatitis was predicted most accurately by the 5 leukocyte cutoff (sensitivity 68.2%, specificity 82.1% and area under the receiver operating characteristics curve 0.75). CONCLUSIONS In asymptomatic men with mild increases of prostate specific antigen histological evidence of prostatic inflammation is common. The leukocyte count in post-prostatic massage urine appears to be useful for screening of this condition before biopsy. Our data suggest that 10 leukocytes per high power field in post-prostatic massage urine, the usually applied cutoff, may be too high for the definition of prostatic inflammation.

196 DOES STRUCTURED WITHDRAWAL OF DESMOPRESSIN IMPROVE RELAPSE RATES IN MONOSYMPTOMATIC ENURETICS: PRELIMINARY RESULTS OF A PROSPECTIVE RANDOMIZED MULTICENTRE PLACEBO CONTROLLED STUDY?

Parviz Hajiyev*, Berk Burgu, Evren Suer, Yusuf Kibar, Ankara, Turkey; Mesrur Selcuk Silay, Istanbul, Turkey; Serhat Gurocak, Hasan Serkan Dogan, Hasan Cem Irkilata Irkilata, Ankara, Turkey; Tayfun Oktar, Bulent Onal, Istanbul, Turkey; Erim Erdem, Mersin, Turkey; Yuksel Cem Aygul, Ankara, Turkey; Cem Balcý, Ahmet Ruknettin Aslan, Istanbul, Turkey; Tarkan Soygur, Ankara, Turkey; Þaban Sarýkaya, Samsun, Turkey; Serdar Tekgul, Ankara, Turkey