Ajay L. Mahajan
Derriford Hospital
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Featured researches published by Ajay L. Mahajan.
Plastic and Reconstructive Surgery | 2011
Katrin Seidenstuecker; Beatrix Munder; Ajay L. Mahajan; Philipp Richrath; Philipp Behrendt; Christoph Andree
Background: Although free tissue-transfer with the deep inferior epigastric perforator (DIEP) flap is one of the best forms of autologous breast reconstruction, surgeons have remained guarded over selecting patients for the procedure in the presence of comorbid conditions. This study has investigated the relevance of these conditions. Methods: A prospective review of all free flap breast reconstructions (n = 624) was performed over a 2-year period at the Department of Plastic Surgery at the Sana Kliniken Düsseldorf. Patients were placed into three groups based on comorbid conditions such as age 65 years or older, active smoking, and body mass index greater than or equal to 30. Flap and donor-site complications were analyzed. Results: Six hundred twenty-four breast reconstructions with DIEP or muscle-sparing transverse rectus abdominis musculocutaneous (TRAM) flaps were performed in 558 patients (66 bilateral reconstructions). There were 36 patients older than 65 years at the time of surgery, 94 active smokers, and 79 patients with a body mass index of greater than or equal to 30. Flap complications such as venous congestion (n = 5), partial flap loss (n = 10), marginal necrosis (n = 15), and total flap loss (n = 5) occurred in 35 cases (5.6 percent). Donor-site complications such as delayed abdominal wound healing (n = 9), seroma (n = 8), abdominal hernia (n = 3), and bulging (n = 11) occurred in 31 cases (5 percent). Conclusions: Despite having significantly higher complications in the form of delayed donor-site wound healing in active smokers and higher total flap loss in obese patients, the overall complication rates compared with other reconstructive procedures are low. Microsurgical reconstruction with DIEP and muscle-sparing TRAM flaps is associated with low complication rates, excellent aesthetic outcome, and high patient satisfaction, even in patients with known risk factors.
Plastic and Reconstructive Surgery | 2006
Brigitte Pittet; Ajay L. Mahajan; Navid Alizadeh; Kai-Uwe Schlaudraff; Jean Fasel; Denys Montandon
Background: The serratus anterior flap is commonly used without its cutaneous component and is covered with a skin graft. The authors have successfully used the free serratus anterior flap along with its skin paddle and have found it to be valuable for reconstruction of the face. Methods: Fresh cadaveric dissections and arteriography were performed to identify perforator vessels to the skin overlying the muscle. Clinically, free transfer of the musculocutaneous flap to the face was carried out in 27 patients, mostly for severe noma (infection) sequelae. Results: Anatomical dissection and arteriography revealed no cutaneous perforator vessels directly communicating with the vascular pedicle of the muscle. However, large perforators from the intercostal vessels were found passing through the muscle to reach the skin. In the clinical cases, flap survival was 100 percent in 24 patients. Conclusions: The serratus anterior musculocutaneous flap is reliable and particularly well-suited for reconstruction of the face, and has many advantages. The authors speculate that the skin paddle may be vascularized by perforators from the intercostal vessels communicating with the thoracodorsal pedicle through intramuscular choke vessels.
Plastic and Reconstructive Surgery | 2010
R. Sinna; Armand Boloorchi; Ajay L. Mahajan; Quentin Qassemyar; M. Robbe
Summary: In spite of the Gent consensus on perforator flap terminology, widespread confusion still exists regarding the true description of these flaps, making it hard to understand these surgical procedures in comparison with conventional flap techniques. The value of perforator flaps can be better understood by further clarifying certain aspects of previous descriptions. The authors would like to propose enriching the standard Gent nomenclature with optional terms that specify additional aspects of the perforator flap such as including the vessel of origin, the type of vascular dissection, the muscle involved, and the type of perforator vessel. When describing a new flap, these terms will help clarify the anatomical aspects and the surgical approach. Lastly, a better understanding will help in the ongoing debates on this type of surgery and will aid in its dissemination and adoption into reconstructive practice.
Plastic and Reconstructive Surgery | 2012
Ajay L. Mahajan; Assaf Zeltzer; Karel E. Y. Claes; Koenraad Van Landuyt; Moustapha Hamdi
Background: Abdominal incisions and their subsequent scarring alter the vascular architecture of the abdominal pannus. This is of significance when reconstructing the breast with the deep inferior epigastric perforator (DIEP) flap. This study aimed to objectively investigate the impact of the lower abdominal Pfannenstiel scar in utilizing the DIEP flap. Methods: A retrospective study of breast reconstruction with DIEP flaps was conducted on patients who had a Pfannenstiel scar (n = 36) compared with patients who did not (n = 36). Computed tomography angiograms were analyzed for the numbers, positions, and dimensions of perforator vessels. Influence of the scar on the reconstructive outcome was assessed. Results: The number of perforators was greater in the control group (mean, 9.14) compared with the study group (mean, 8.3) but was not significant, with marginal significance (p = 0.09). The percentage of found perforators with 4 mm or greater was significantly higher in the study group than in the control group (21.7 percent compared with 14.3 percent, respectively; p = 0.04). The position of perforators was more or less the same, and complications were also comparable in both groups. Conclusions: Pfannenstiel incisions result in undermining of the lower abdominal apron and, in most cases, division of the superficial epigastric vessels. This results in “ischemic preconditioning” of the flap, as has been evidenced by the increased dimensions of the perforators. Hence, flaps raised from these abdomens are not only safe but may even be better vascularized. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.
Journal of Surgical Research | 2009
Xavier Tenorio; Ajay L. Mahajan; Reto Wettstein; Yves Harder; Marek Pawlovski; Brigitte Pittet
BACKGROUND Early recognition of perfusion failure is critical for free flap salvage. However, most of the different methods assessing perfusion have limitations and have not gain widespread acceptance. The aim of this study was to evaluate a novel system, a combination of a highly sensitive infrared camera with dynamic infrared image processing, in an animal flap model. MATERIALS AND METHODS Flaps based on the inferior superficial epigastric vessels were raised bilaterally in 20 rats. One pedicle artery or vein was ligated and the contralateral side served as unligated control. Thermographic measurements were performed before and after ligation yielding a color map and a temperature recording. The macroscopic evolution of the flap was photographically documented. RESULTS All vascular occlusions were rapidly detected. In the artery ligated group, the disappearance of the hot spot, corresponding to the pedicle, was observed in absence of macroscopic changes of the flap. In animals undergoing venous ligation, changes in the thermographic image preceded clinical signs of congestion. Temperature recordings between arterial and venous ligation were not significantly different. CONCLUSIONS Vascular compromise was rapidly and consistently identified prior to appearance of macroscopic changes. This very sensitive system allows for a precise detection of small differences of infrared emission within the flap visualized as changes in the color map with disappearance of the hot spot on the color map. This is independent of absolute temperature values that are influenced by environmental factors. In addition to postoperative monitoring, the set-up may be a promising tool for preoperative planning of perforator flaps.
Annals of Plastic Surgery | 2011
Xavier Tenorio; Ajay L. Mahajan; Badwi Elias; Julie Schaepkens van Riempst; Reto Wettstein; Yves Harder; Brigitte Pittet
Background:Dynamic Infrared Imaging (DIRI) is a noninvasive technique that precisely analyzes the infrared radiation of any object. We used this technique to locate the dominant perforator vessels in flap surgery in conjunction with conventional Doppler. Methods:Ten patients scheduled for deep inferior epigastric artery perforator flap and 6 for free-fibular flaps were selected. Perforator vessels were localized in the donor area, using Doppler and DIRI. The ability to locate the dominant perforators was compared between both techniques. Results:DIRI produced a precise map showing the location of the perforators and their area of perfusion at the skin level. Their dominance can be determined by their size. Flow Doppler located the perforators at the aponeurotic level without size and perfusion information. Conclusions:DIRI produces a skin thermographic map of perforator vessels and their perfusion area. Handheld Doppler locates perforators at the aponeurotic level. Their combination increases safety in the planning of perforator flap surgery.
Journal of Burn Care & Research | 2006
Thomas W.L. Chapman; Devendra Mahadevan; Ajay L. Mahajan; Alvaro Perez-Temprano; James R. McDiarmid
A case of iatrogenic full-thickness chemical burns from monochloroacetic acid (MCA) crystal application is described, followed by a brief review of the relevant literature and discussion of both local and systemic problems that may be encountered with absorption of this chemical. We believe this to be the first reported case of full-thickness burns in association with MCA. The degree of injury and systemic side effects encountered as a procedure complication highlights the importance of using this chemical with care in any clinical setting. In addition, an apparent predilection of MCA for the germinal matrix as found in this case may further complicate reconstructive options for associated injuries.
The Breast | 2016
Katrin Seidenstuecker; Carl Van Waes; Beatrix Munder; Karel Claes; Christian Witzel; Nathalie Roche; Filip Stillaert; Ajay L. Mahajan; Christoph Andree; Phillip Blondeel
BACKGROUND Breast cancer is the commonest form of cancer in women affecting almost a quarter of a million patients in the US annually. 30 percent of these patients and patients with genetic mutations undergo removal of the breast, as highlighted in a high profile celebrity patient. Although breast reconstruction with free microvascular transfer of a DIEAP flap from the abdomen is an ideal form of reconstruction, there have been misgivings about the complexity and potential complications. This study was aimed at clearing these misunderstandings and establishing the value of this form of breast reconstruction. METHODS 1036 DIEAP flap breast reconstructions carried out at the University Hospital, Gent (five year period) and at the Sana Kliniken, Düsseldorf (three year period) were included prospectively. Comorbid factors like chemotherapy, radiotherapy, patient age >65 years, BMI >30 and smoking were recorded. Outcomes were evaluated over a mean follow up of 2 years. RESULTS Overall complication rate related to the reconstructed breast and donor abdominal area was 6.8 percent. Total flap loss was seen in only 0.8 percent. The mean operating time was less than five hours. Older age, higher BMI, chemotherapy and radiotherapy did not have a significant influence on complication rates, however smoking resulted in significant delay in wound healing in the breast (p = 0.025) and abdominal wounds (p = 0.019). CONCLUSION The DIEAP flap is an excellent option for breast reconstruction, with a low level of donor site morbidity and complications. It is an autologous reconstruction that provides a stable long term result.
Annals of Plastic Surgery | 2014
James M. Taylor; Ruchika Rajan; John K. Dickson; Ajay L. Mahajan
BackgroundWedge resections of the helical rim may result in a significant deformity of the ear with the ear not only smaller but cupped and prominent too. Our technique involves resection of the wedge in the scaphal area without extending into the concha followed by advancement of the helical rim into the defect. This technique is most suitable for peripheral defects of the helical rim, in the middle third. MethodsOur modified surgical technique was applied to reconstruction of the pinna after resection of the tumor in 12 patients. Free cartilaginous helical rim, length of helical rim to be resected, and projection of the ear from the mastoid was measured. This was then compared with measurements after the operation, and the patient satisfaction assessed with a visual analog scale. ResultsThe free cartilaginous rim was 91.67 ± 5.61 mm. Of this, 21.92 ± 3.78 mm was resected, which amounted to 23.84% ± 3.35% of the rim. Although this resulted in a mean increase in ear projection of 6.42 ± 1.68 mm, the aesthetic outcome was good (visual analog scale, 9.08 ± 0.9). ConclusionsThis technique reduces cupping and does not make the ear as prominent as it may do after a conventional wedge resection and results in high patient satisfaction.
Plastic and Reconstructive Surgery | 2011
Carl Van Waes; Katrin Seidenstuecker; Ajay L. Mahajan; Nathalie Roche; Filip Stillaert; Christoph Andree; Phillip Blondeel
IntroductIon: Besides the high incidence of breast cancer, more women are diagnosed with BRCA gene mutations. This has further increased the number of patients, in our practice who undergo therapeutic or prophylactic mastectomy combined with an immediate autologous breast reconstruction. Although the Deep Inferior Epigastric Aretery Perforator (DIEAP) flap has evolved as the ‘workhorse’ flap for autologous breast reconstruction, establishing it as a gold standard has been slow to come. Some earlier smaller and retrospective studies have variably reported on operative times and high complication rates, specifically high revision rates, fat necrosis and flap loss rates. This prospective study aimes at weighing up the pros and cons of this procedure to clearly define its safety and position in today’s reconstructive armamentarium.