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Dive into the research topics where Akifumi Higuchi is active.

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Featured researches published by Akifumi Higuchi.


Cancer Letters | 1999

Detection of cerebroside sulfotransferase mRNA in human gastric mucosa and adenocarcinoma

Takahiko Kobayashi; Koichi Honke; Izumi Tsunematsu; Hidetoshi Kagaya; Shuji Nishikawa; Kaku Hokari; Mototsugu Kato; Hiroshi Takeda; Toshiro Sugiyama; Akifumi Higuchi; Masahiro Asaka

Sulfatide is a major acidic glycolipid in human gastric mucosa, and its sulfation is catalyzed by cerebroside sulfotransferase (CST). To investigate the expression of the CST gene in human gastric cancer, a reverse transcription PCR method was developed with the use of endoscopic bioptic specimens. By this method, we examined the CST mRNA expression in 11 cases of gastric cancer, and in all the cases we detected various levels of the expression both in cancer tissues and in uninvolved adjacent tissues. The present assay method was suggested to be useful in the detection of CST mRNA from a limited amount of bioptic samples.


Journal of Medical Virology | 2001

Cryoglobulinemia in Japanese patients with chronic hepatitis C virus infection: Host genetic and virological study

Atsushi Nagasaka; Tomoya Takahashi; Tsuyoshi Sasaki; Kyoko Takimoto; Kencho Miyashita; Michio Nakamura; Osamu Wakahama; Shuji Nishikawa; Akifumi Higuchi


Acta Gastro-Enterologica Belgica | 2000

CARCINOID TUMOR OF THE ESOPHAGUS : REPORT OF A CASE

Osamu Wakahama; Shuji Nishikawa; Kencho Miyashita; Takahiko Kudou; Atsushi Nagasaka; Akifumi Higuchi


Kanzo | 2005

A case of primary biliary cirrhosis with sarcoid reaction in the regional lymph nodes after surgery of early gastric cancer

Tadashi Yoshida; Atsushi Nagasaka; Yayoi Ogawa; Syuji Nishikawa; Akifumi Higuchi


The Japanese journal of gastro-enterology | 2004

Malignant lymphoma of the pancreas with chronic hepatitis C

Takagi K; Nishikawa S; Atsushi Nagasaka; Akifumi Higuchi; Satoh H


The Japanese journal of gastro-enterology | 2000

[An alpha-fetoprotein and PIVKA-II producing carcinoma of the colon: report of a case].

Miyashita K; Atsushi Nagasaka; Nakanishi M; Kudo T; Wakahama O; Nishikawa S; Akifumi Higuchi; Sato H


Kanzo | 1997

A quantitative evaluation of liver fibrosis on hepatitis C.

Takashi Matsunaga; Osamu Wakahama; Shuji Nishikawa; Akifumi Higuchi; Fumiyuki Koike


Japanese Journal of Thrombosis and Hemostasis | 1981

Studies on abnormal fibrinogen in several hepatic diseases

Akifumi Higuchi; Keisuke Sakurada; Tamotsu Miyazaki


Japanese Journal of Pharmaceutical Health Care and Sciences | 2005

Comparison of Blood Cell Changes between Interferon Alpha Monotherapy and Interferon Alpha Combination Therapy with Ribavirin in Patients with Chronic Hepatitis C

Michiya Kobayashi; Rinako Sawazaki; Hiroshi Saitoh; Kentarou Hara; Takao Kurosawa; Yoshikazu Gotoh; Asuka Yamamoto; Shinji Iwai; Kohji Tadano; Yasushi Takahashi; Atsushi Nagasaka; Akifumi Higuchi


Acta Gastro-Enterologica Belgica | 2005

Cationic trypsinogen 遺伝子変異を認めた遺伝性膵炎の一家系

Kikuko Takagi; Shuji Nishikawa; Atsushi Nagasaka; Akifumi Higuchi

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Hiroshi Saitoh

Health Sciences University of Hokkaido

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Isao Maekawa

Asahikawa Medical College

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