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Featured researches published by Akihiko Hara.


Surgical Endoscopy and Other Interventional Techniques | 1995

Laparoscopic splenectomy in children

Kazuhiko Yoshida; Yoji Yamazaki; Ryoji Mizuno; H. Yamadera; Akihiko Hara; Jyoji Yoshizawa; Masaki Kanai

To determine the safety and efficiacy of laparoscopic splenectomy (LS) in children, a retrospective review of our preliminary experience using LS was compared to results in patients who previously underwent open splenectomy (OS). From July 1993 to January 1995, we performed eight LS procedures in six children with hereditary spherocytosis (HS) and two with immune thrombocytopenic purpura (ITP). Laparoscopic cholecystectomy was simultaneously done in one case with HS. There were 4 males and 4 females who ranged in age from 5 to 15 years—an average age of 8.8 years. Two cases in the early series required a counterincision because of bleeding. Eleven patients who previously underwent OS in our department were used to compare demographics, operative courses, and surgical outcomes. The ages, genders, diseases, body weights, and spleen weights were comparable between LS group and OS groups. The operative time for the LS group was statistically longer than for the OS group (226±24 min vs 101±8 min, P<0.001). The estimated blood loss in the LS group was similar to that of the OS group (100±39 ml vs 73±11 ml, P=0.97). There were no peri- or postoperative complications in two groups. The postoperative hospital stay of LS group was statistically shorter than that of the OS (6.8±0.6 days vs 10.4±0.5 days, P<0.001). LS provided better cosmesis and minimized trauma in children over OS. LS appears to be a safe and effective procedure in children, and is useful in the management of pediatric patients with HS or ITP.


Pediatric Surgery International | 1994

Hemostasis for the Ramstedt procedure: Use of a fibrin adhesive

Yoji Yamazaki; Tsuginori Yoshida; Ryoji Mizuno; Shoji Yuno; Akihiko Hara; Jyoji Yoshizawa; Kenji Sakurai

Pre- and postoperative blood counts were retrospectively compared between patients with no hemostatic management (group A,n = 30) and patients with a fibrin adhesive (Beriplast P) applied to the cut edges (group B,n = 8) when pyloromyotomy was performed for hypertrophic pyloric stenosis. Postoperative red blood cell count, hematocrit, and hemoglobin were significantly decreased in group A (P <0.01) while there was no significant change in group B. It has been stated that the Ramstedt operation does not require any special hemostatic management. However, as postoperative peritoneal bleeding is suspected, hemostatic management with a fibrin adhesive applied to the incised region of the serosa and muscle layer is recommended.


Surgical Endoscopy and Other Interventional Techniques | 1995

Laparoscopic splenectomy in children. Preliminary results and comparison with the open technique.

Kazuhiko Yoshida; Yoji Yamazaki; Ryoji Mizuno; H. Yamadera; Akihiko Hara; Jyoji Yoshizawa; Masaki Kanai


American Journal of Physiology-lung Cellular and Molecular Physiology | 2005

Congenital diaphragmatic hernia, tracheal occlusion, thyroid transcription factor-1, and fetal pulmonary epithelial maturation

Cheryl J. Chapin; Robert Ertsey; Jyoji Yoshizawa; Akihiko Hara; Lourenco Sbragia; John J. Greer; Joseph A. Kitterman


Journal of Surgical Research | 2000

Inhibitory Effect of TNP-470 on Hepatic Metastasis of Mouse Neuroblastoma

Jyoji Yoshizawa; Ryoji Mizuno; Tsuginori Yoshida; Akihiko Hara; Syuichi Ashizuka; Masaki Kanai; Naruo Kuwashima; Masashi Kurobe; Yoji Yamazaki


Archives of Surgery | 1999

The Value of Acute-Phase Protein Measurements After Curative Gastric Cancer Surgery

Tetsuji Fujita; Akihiko Hara; Yoji Yamazaki


Journal of Pediatric Surgery | 2004

Successful in utero gene transfer using a gene gun in midgestational mouse fetuses

Jyoji Yoshizawa; Xiano-Kand Li; Masayuki Fujino; Hiromitu Kimura; Ryoji Mizuno; Akihiko Hara; Syuichi Ashizuka; Masaki Kanai; Naruo Kuwashima; Masashi Kurobe; Yoji Yamazaki


Pediatric Endosurgery and Innovative Techniques | 2000

Laparoscopic Evacuation of Ovarian Cyst Followed by Cystectomy

Kazuhiko Yoshida; Yoji Yamazaki; Ryuzo Murai; Akihiko Hara; Jyoji Yoshizawa; Shuichi Ashizuka; Nomi Kuwashima


Jpn J Gastroenterol Surg, Nihon Shokaki Geka Gakkai zasshi | 2001

A Case Report of Escherichia Coli O157 Infection, Which was Difficult to Discriminate from Intussusception.

Yuichi Ishida; Susumu Kobayashi; Akihiko Hara; Yoji Yamazaki; Teruaki Aoki


Archive | 2015

nitrofen-induced congenital diaphragmatic hernia Fetal tracheal occlusion in the rat model of

Paul Davies; N. Scott Adzick; W Alan; Tommy Seaborn; Stéphane Guay; Bruno Piedboeuf; Joseph A. Kitterman; Cheryl J. Chapin; Robert Ertsey; Jyoji Yoshizawa; Akihiko Hara; Lourenco Sbragia; John J. Greer

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Yoji Yamazaki

Jikei University School of Medicine

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Ryoji Mizuno

Jikei University School of Medicine

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Masaki Kanai

Jikei University School of Medicine

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Kazuhiko Yoshida

Jikei University School of Medicine

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Naruo Kuwashima

Jikei University School of Medicine

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Tsuginori Yoshida

Jikei University School of Medicine

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Kenji Sakurai

Jikei University School of Medicine

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Masashi Kurobe

Jikei University School of Medicine

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