Akihiko Yagura

Determination of tumor marker levels in cystic fluid of benign liver cysts

The levels of tumor markers in cystic fluid and serum were measured in six patients with benign biliary cyst of the liver. AFP in the cystic fluid was lower than the upper normal limit for serum in all cases, and CEA in the cystic fluid was higher than the upper normal limit for serum in one of the six cases. CA19-9, DU-PAN 2, and SPAN 1 in cystic fluid were much higher than the upper normal limit for serum in all cases (more than 100-fold for CA19-9, twofold for DU-PAN 2, and ninefold for SPAN 1). CA19-9, DU-PAN 2, and SPAN 1 in cystic fluid were significantly higher than the levels in the corresponding serum. Positive immunohistochemical staining against CA19-9, DU-PAN 2, and SPAN 1 was observed in the cytoplasm of the epithelial cells of the cyst wall. These results suggested that the high concentrations of CA19-9, DU-PAN 2, and SPAN 1 in the cystic fluid were due to secretion from the epithelial cells in the benign biliary cysts.

Hemodynamic Alterations during Laparoscopic Cholecystectomy

Serial changes of hemodynamic parameters were investigated using a Swan-Ganz catheter in 14 patients undergoing laparoscopic cholecystectomy (LAP) and 12 patients undergoing mini-laparotomy cholecyste

A case of pancreatic cyst containing gall sludge

SummaryA case of acquired retention cyst of the pancreas containing gall sludge was reported. Gallstones or gall sludge recognized in pancreatic cysts has not been reported. Histological examination suggested that the gall sludge in the pancreatic cyst was caused by the reflux of bile into the pancreatic duct through the papilla of Vater. However, endoscopic retrograde cholangiopancreatography showed no anomalous junction of the pancreatico-biliary ductal system. Crystallization of the components of bile can occur in the pancreas even in a case without anomalous junction of the pancreatico-biliary ductal system.

Respiratory Movement of the Membranous Part of the Trachea after Thoracic Esophagectomy

Respiratory movement of the membranous part of the trachea was investigated using cineradiography 3 days and 1 month after operation in 10 patients who underwent thoracic esophagectomy through a right

Fibrin glue for postoperative persistent cutaneous fistula

In 14 patients with persistent external fistulas after an operation on the digestive system, percutaneous injection of fibrin glue was attempted for the purpose of immediate closing of the fistula on