Akira Kamitamari
Nagasaki University
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Publication
Featured researches published by Akira Kamitamari.
Clinical Transplantation | 2004
Yuichi Shinkoda; Osamu Ijichi; Takayuki Tanabe; Shuji Ishikawa; Akira Kamitamari; Takuroh Nishikawa; Naoaki Ikarimoto; Yoshifumi Kawano
Abstract: We report here the reconstitution after bone marrow transplantation (BMT) in identical infant twins with acute myelogenous leukemia (AML). They were diagnosed at 8 and 9 months of age. Complete remission was induced after two courses of chemotherapy. After four and five courses of chemotherapy, respectively, they received BMT at 2‐month interval from the same HLA‐identical older brother. The total dose of marrow nucleated cells (NC) harvested was 77.7 × 108. The first patient was transplanted with half of the total dose of NC. The remaining cells were cryopreserved without the use of a programmed freezer and transplanted into the second patient 2 months later. The number of days for neutrophil (>0.5 × 109/L), platelet (>50 × 109/L), and reticulocyte (>1%) recovery were, respectively, 15, 21, and 14 in the first case and 12, 21, and 15 in the second case. The clinical courses after BMT were uneventful in both cases, except for mild acute GVHD, and complete remission has been maintained >4 yr with full recovery of immune and marrow function. Based on the results in these cases, we confirmed that marrow cells that have been cryopreserved without the use of a programmed freezer could reconstitute immune and marrow function as well as non‐cryopreserved cells.
International Journal of Hematology | 2010
Akimichi Ohsaka; Atsushi Kikuta; Hitoshi Ohto; Akira Ohara; Akaru Ishida; Koji Osada; Tetsunori Tasaki; Akira Kamitamari; Asayuki Iwai; Shunro Kai; Taira Maekawa; Yasutaka Hoshi
Granulocyte transfusion (GTX) has recently been revived by the ability to stimulate granulocyte donors with granulocyte colony-stimulating factor (G-CSF), resulting in a greatly increased number of cells that can be collected. However, there is a paucity of guidelines for assessing the appropriateness and safety management of GTX. The objective of this study was to establish guidelines for the safety management of GTX appropriate for the clinical situation in Japan. The Japan Society of Transfusion Medicine and Cell Therapy, Granulocyte Transfusion Task Force issued the first version of guidelines for GTX considering the safety management of both granulocyte donors and patients who receive GTX therapy. The current guidelines cover issues concerning: (1) the appropriateness of medical institutions, (2) management of granulocyte donors, (3) quality assurance of granulocyte concentrates, (4) administration of granulocyte concentrates, (5) evaluation of the effectiveness of GTX therapy, and (6) complications of GTX therapy. The simple ‘bag separation method’ without apheresis may be recommended for granulocyte collection in pediatric patients. The first version of guidelines for GTX therapy has been established, which may be appropriate for the clinical situation in Japan. Care should be taken to perform the safety management of both granulocyte donors and patients who receive GTX therapy.
Journal of Pediatric Surgery | 2008
Izumi Muraoka; Yasuharu Ohno; Akira Kamitamari; Masahiko Okada; Hiroyuki Moriuchi; Takashi Kanematsu
Infantile myofibromatosis (IM) is a rare soft tissue tumor of infancy and childhood. We report the case of a newborn girl with an abdominal tumor discovered at 32 weeks of gestation by fetal ultrasound. She underwent a laparotomy for an unexplained abdominal mass 20 days after birth. The tumor originated from the spleen and was removed by splenectomy. There were no other abnormal findings on diagnostic modalities. Based on the histological examinations, the tumor was diagnosed as an IM. Although extremely rare during the neonatal period, solitary type IM should be considered as a differential diagnosis of the splenic tumor.
Journal of Pediatric Surgery | 2008
Yasuharu Ohno; Katsumi Tanaka; Takashi Kanematsu; Mitsuru Noguchi; Masahiko Okada; Akira Kamitamari; Nobuyuki Hayashi
BACKGROUND In the treatment of pelvic tumors, pelvic floor defects owing to a wide excision tend to increase the occurrence of such morbidities as radiation injury. The reconstruction of these defects would minimize the risk of such morbidities. Authors introduce a new technique for repairing a pelvic floor defect using a tensor fascia lata flap. METHODS Two boys, 4 years old and 10 months old, presenting with pelvic rhabdomyosarcoma underwent a tumor extirpation associated with a wide excision of the pelvic organs. After the removal of the tumor, a tensor fascia lata flap was designed on the right thigh. The pedicled rotation flap was subcutaneously elevated, guided to the intraperitoneal cavity, and was fixed to cover the superior aperture of the lesser pelvis. RESULTS The flaps functioned well, and postoperative radiation therapies consisting of 45 and 41.4 Gy to the lesser pelvic cavity were carried out without any complications. As a result, the necessary postoperative protocol combination therapies could be successfully performed in a timely manner. CONCLUSION The pedicled tensor fascia lata flap is considered to be an alternative option for the stable repair of pelvic floor defects to prevent radiation injury.
Hukuoka acta medica | 2004
Ando C; Moriyama K; Nakashima Y; Ohmiya A; Hirofumi Yoshikuni; Hiroyuki Moriuchi; Tsuji Y; Yuzo Ohba; Yukio Hattori; Akira Kamitamari
A 20-year-old man has been under observation for 18 years because of unstable hemoglobinemia, Hb Buenos Aires, Bryn Mawr (beta-globin, Phe85Ser). At the age of 19 years, he was hospitalized because of fever and hemolytic crisis, and the symptoms resolved after infusion of antibiotics. Nucleotide sequencing of the beta-globin gene confirmed that the patient was heterozygous for the mutation. The patients erythrocytes showed an increased affinity for oxygen and a prolonged glycerol lysis time. We review a previously reported single family and 5 other cases, and discuss the clinical significance of splenectomy and plasma-derived haptoglobin.
Journal of Pediatric Surgery | 2006
Kyoko Mochizuki; Yasuharu Ohno; Yukiko Tokai; Takashi Kanematsu; Masahiko Okada; Akira Kamitamari; Hiroyuki Moriuchi; Mitsuru Noguchi; Tomayoshi Hayashi
Leukemia & Lymphoma | 2002
Tomomi Okamoto; Shouhei Yokota; Naoyuki Katano; Seriu T; Makoto Nakao; Masafumi Taniwaki; Arata Watanabe; Keiko Asami; Atsushi Kikuta; Shoichi Koizumi; Tetsuo Kawakami; Shigeru Ohta; Munenori Miyake; Tsutomu Watanabe; Asayuki Iwai; Akira Kamitamari; Osamu Ijichi; Nobuyuki Hyakuna; Junichi Mimaya; Takeo Fujimoto; Masahito Tsurusawa
Liver Transplantation | 2005
Ryoko Honda; Yasuharu Ohno; Takuya Iwasaki; Sadayuki Okudaira; Masahiko Okada; Akira Kamitamari; Koichi Ohshima; Hiroyuki Moriuchi; Takashi Kanematsu
Internal Medicine | 2009
Yasuaki Yamada; Masahiko Okada; Akira Kamitamari; Hiroyuki Moriuchi; Masanori Yanai; Osamu Hano; Kunihiro Tsukasaki; Kazuto Tsuruda; Hiroo Hasegawa; Katsunori Yanagihara; Shimeru Kamihira
Medical and Pediatric Oncology | 2002
Kei Izumi; Chyuns Yun; Noriko Miyake; Masahiko Okada; Akira Kamitamari; Hiroyuki Moriuchi