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Featured researches published by Akram Hernández-Vásquez.


Journal of The European Academy of Dermatology and Venereology | 2017

Psoriasis in Latin America and the Caribbean: a systematic review

Akram Hernández-Vásquez; L. Molinari; N. Larrea; A. Ciapponi

Psoriasis is a chronic inflammatory disease that generally affects the skin, nails and joints. The burden of psoriatic disease in Latin America and the Caribbean (LAC) remains largely unknown. To estimate the burden of psoriasis in LAC. We conducted a systematic review following the MOOSE and PRISMA statements. We searched published studies in MEDLINE, EMBASE, LILACS and CENTRAL from 1st January 2000 to 5th August 2015. We included studies that reported incidence, prevalence, health resource use and health expenditures, treatment patterns, comparative effectiveness of different drugs, patients reported outcomes, adherence to treatment and patient preferences in LAC. Risk of bias was assessed evaluating selection of participants, control of cofounders, measurement of exposure and outcome and conflict of interest. Pairs of reviewers independently selected, extracted and assessed the bias risk of the studies. The systematic review was registered at PROSPERO (CRD42016038325). A total of 18 studies from 12 LAC countries were included. Most were observational studies, between which there was a large heterogeneity of outcomes. Population‐based studies were not found and most data came from hospital registries. One study reported an incidence of psoriatic arthritis in 6.26 cases per 100 000 person‐years. Another study found an incidence of psoriasis 1020 per 100 000 patient‐year attending at a dermatology clinic. The prevalence reported in the Argentinean health service was 74 cases per 100 000. Further, psoriasis has been shown to have a substantial negative impact on quality of life. A number of studies also indicated that non‐communicable disease burden increases with the presence and severity of psoriasis. With regard to treatment pattern, methotrexate was the dominant systemic therapy. In conclusion, there is an important lack of information from LAC concerning the burden of psoriasis. Further studies investigating the burden of psoriasis in representative LAC populations are needed.


Salud Colectiva | 2016

Acceso a servicios de salud dental en menores de doce años en Perú, 2014

Akram Hernández-Vásquez; Diego Azañedo; Deysi Díaz-Seijas; Guido Bendezú-Quispe; Hugo Arroyo-Hernández; Stalin Vilcarromero; Andrés A. Agudelo-Suárez

The aim of the study was to explore the patterns of dental health services access in children under twelve years of age in Peru. Data from 25,285 children under 12 years who participated in the Demographic and Family Health Survey of 2014 were reviewed. An exploratory spatial analysis was performed to project the proportions of children with access to dental health services, according to national regions, type of health service and urban or rural place of residence. The results show that of the total sample, 26.7% had access to dental health services in the last six months, 39.6% belonged to the age group 0-4 years, 40.6% lived in the Andean region and 58.3% lived in urban areas. The regions of Huancavelica, Apurimac, Ayacucho, Lima and Pasco had the highest percentages of access nationwide. In conclusion, there is low access to dental health services in the population under 12 years of age in Peru. The spatial distribution of access to dental health services allows regions to be identified and grouped according to similar access patterns, in order to better focus public health actions.


Revista Peruana de Medicina Experimental y Salud Pública | 2016

Análisis espacial del sobrepeso y la obesidad infantil en el Perú, 2014

Akram Hernández-Vásquez; Guido Bendezú-Quispe; Deysi Díaz-Seijas; Marilina Santero; Nicole Minckas; Diego Azañedo; Daniel A. Antiporta

Objectives. To estimate regional prevalence and identify the spatial patterns of the degree of overweight and obesity by districts in under five years children in Peru during 2014. Materials and methods. Analysis of the information reported by the Information System Nutritional Status (SIEN) of the number of cases of overweight and obesity in children under five years recorded during 2014. Regional prevalence for overweight and obesity, and their respective confidence intervals to 95% were calculated. Moran index was used to determine patterns of grouping districts with high prevalence of overweight and/or obesity. Results. Data from 1834 districts and 2,318,980 children under five years were analyzed. 158,738 cases (6.84%; CI 95%: 6.81 to 6.87) were overweight, while 56,125 (2.42%; CI 95%: 2.40 to 2.44) obesity. The highest prevalence of overweight were identified in the regions of Tacna (13.9%), Moquegua (11.8%), Callao (10.4%), Lima (10.2%) and Ica (9.3%), and in the same regions for obesity with 5.3%; 4.3%; 4.0%; 4.0% and 3.8% respectively. The spatial analysis found grouping districts of high prevalence in 10% of all districts for both overweight and obesity, identifying 199 districts for overweight (126 urban and 73 rural), and 184 for obesity (136 urban and 48 rural). Conclusions. The highest prevalence of overweight and obesity were identified in the Peruvian coast regions. Moreover, these regions are predominantly exhibited a spatial clustering of districts with high prevalence of overweight and obesity.


Salud Colectiva | 2018

Análisis espacial y del entorno físico de accidentes de tránsito en la ciudad de Resistencia, Chaco, Argentina

Martín Chaparro; Akram Hernández-Vásquez; Alejandro Parras

Traffic accidents are an emerging problem in cities with high mobility and little urban planning. Evidence is lacking in Argentina regarding the relationship between the environment and accident occurrence; we therefore conducted a geospatial analysis and estimated the risk of accidents and their possible association with the characteristics of the physical environment in the city of Resistencia, Argentina occurring in 2012. Kernel density estimates were used for the spatial distribution of accidents and in parallel an observational, analytical study was carried out to analyze the factors associated with accident occurrence. The results show three critical areas (in the northwest, center and south of the city) with greater accident frequency. Environmental factors that were associated with the occurrence of accidents were the presence of street lighting (23% greater), the presence of a tree close to the road (47% greater), the presence of a traffic light (28% greater), and if the road was a major avenue (122% greater) and had curves (129% greater). This study shows the city of Resistencia to be in a situation of urban vulnerability due not only to its socioeconomic status but also to the unequal development compared to neighboring cities, a reality that fosters an unfavorable environment.


Salud Publica De Mexico | 2017

Guías alimentarias: una opción para seguir enfrentando los problemas nutricionales en el Perú

Diego Eduardo Azañedo-Vilchez; Akram Hernández-Vásquez

Senor editor: Hemos leido con gran interes la carta al editor de Lujan-Carpio y colaboradores, donde abordan el tema de la publicidad televisiva como riesgo latente para el desarrollo de problemas nutricionales junto con una descripcion de experiencias en algunos paises orientadas a su regulacion. Asimismo, los autores reportan que en el Peru la prevalencia de sobrepeso y obesidad infantil es de 33 y 14%, respectivamente; sin embargo, consideramos que dicho valor es excesivo a la luz de las nuevas estimaciones y de los valores reportados en el estudio citado por los autores (6.4 para obesidad y 1.8% para sobrepeso)...


Salud Publica De Mexico | 2017

Respondiendo a una pandemia emergente: Zika y los métodos anticonceptivos como medida preventiva

Akram Hernández-Vásquez; Diego Azañedo; Stalin Vilcarromero

El virus del Zika ha ido expandiendose rapidamente en America Latina y el Caribe. El Peru aun no reporta casos autoctonos, ambientales con los paises afectados pueden establecer las condiciones adecuadas para la infeccion del Aedes aegypti , vector del virus del Zika y su posterior transmision a los humanos, desencadenando una epidemia como la que sucedio con el virus del dengue en anos anteriores. Ademas de la enfermedad febril aguda que el virus produce, la posible asociacion con el incremento de casos de sindrome de Guillain-Barre en adultos, el aumento en la incidencia de microcefalia en recien nacidos, asi como el reporte de la transmision por via sexual, han generado gran preocupacion tanto en la poblacion como en los decisores de la salud publica, a tal grado que la Organizacion Mundial de la Salud (OMS) ha decretado alerta mundial…


Revista Peruana de Medicina Experimental y Salud Pública | 2017

Análisis espacial de la anemia gestacional en el Perú, 2015

Akram Hernández-Vásquez; Diego Azañedo; Daniel A. Antiporta; Sandra Cortés

Objectives To establish regional prevalences of anemia in pregnant women receiving care at public clinics in Peru in 2015 and identify high-prevalence district conglomerates. Materials and Methods An ecological study was carried out on data from pregnant women with anemia registered on the Nutritional Status Information System (SIEN) who received care in 7703 public clinics in 2015. Regional and district prevalences of gestational anemia were calculated. District conglomerates with a high prevalence of gestational anemia were identified using the Moran Index. Results Information was gathered from 311,521 pregnant women distributed in 1638 districts in Peru. The national prevalence of anemia was 24.2% (95% confidence interval [95% CI]: 24.0-24.3%), the rural prevalence was 30.5%, and the urban prevalence was 22.0%. The regions of Huancavelica (45.5%; 95% CI: 44.2-46.7%), Puno (42.8%; 95% CI: 41.9-43.7%), Pasco (38.5%; 95% CI: 36.9-40.0%), Cusco (36.0%; 95% CI: 35.3-36.8%), and Apurímac (32.0%; 95% CI: 30.8-33.1%) had the highest prevalences of anemia. The local Moran Index identified 202 high-priority districts (hot spots) (12.3% of total; 44 urban and 158 rural) located in Ancash, Apurímac, Arequipa, Ayacucho, Cajamarca, Cusco, Huancavelica, Huánuco, Junín, La Libertad, Lima, Pasco, and Puno containing high-prevalence district conglomerates. Conclusions Gestational anemia in Peru has its highest prevalence rates in rural and southern mountainous areas. The district conglomerates with high prevalence rates of gestational anemia coincide with the areas of high regional prevalence.


Revista Peruana de Medicina Experimental y Salud Pública | 2016

Sistemas de información geográfica: aplicación práctica para el estudio de atropellos en el Cercado de Lima, Perú

Akram Hernández-Vásquez; Diego Azañedo; Guido Bendezú-Quispe; Josmel Pacheco-Mendoza; R. Martín Chaparro

The aim of this study was to geospatially explore the occurrence rates of car accidents involving pedestrians in Cercado de Lima (Lima District), Peru. Car accidents involving pedestrians recorded in the 2015 National Police Station Census of the National Statistics and Information Institute were described and georeferenced. Subsequently, a Kernel Density analysis was carried out to locate areas with high, medium, and low density events. Records of 171 car accidents involving pedestrians were studied: the types of vehicles involved were automobiles (56.7%) and smaller vehicles (22.8%). The highest percentage of car accidents involving pedestrians (38.6%) took place between 12:00 p.m. and 5:00 p.m. There were two densely populated areas and two areas with intermediate density for car accidents involving pedestrians, locations that were previously reported as critical due to their deficiencies and high probability of traffic accidents. The use of geographic information systems offers a quick overview of the occurrence rates of car accidents involving pedestrians to make comparisons and enable the local implementation of strategies.


Revista Peruana de Medicina Experimental y Salud Pública | 2016

Carga de enfermedad por tabaquismo e impacto potencial del incremento de precios de cigarrillos en el Perú

Ariel Bardach; Joaquín Caporale; Andrea Alcaraz; Federico Augustovski; Leandro Huayanay-Falconí; César Loza-Munarriz; Akram Hernández-Vásquez; Andres Pichon-Riviere

Objectives . To calculate the burden of smoking-related disease and evaluate the potential economic and health impact of tax-induced cigarette price increase in Peru. Materials and methods. A microsimulation model was used to estimate smoking-attributable impact on mortality, quality of life, and costs associated with heart and cerebrovascular disease, chronic obstructive pulmonary disease, pneumonia, lung cancer, and another nine cancers. Three scenarios, involving increased taxes, were evaluated. Results . A yearly total of 16,719 deaths, 6,926 cancer diagnoses, 7,936 strokes, and 7,548 hospital admissions due to cardiovascular disease can be attributed to smoking in Peru. Similarly, 396,069 years of life are lost each year from premature death and disability, and the cost of treating smoking-attributable health issues rises to 2,500 million soles (PEN 2015). Currently, taxes on tobacco cover only 9.1% of this expense. If cigarette prices were to increase by 50% over the next 10 years, 13,391 deaths, 6,210 cardiovascular events, and 5,361 new cancers could be prevented, representing an economic benefit of 3,145 million (PEN) in savings in health costs and increases in tax revenues. Conclusions . Smoking-attributable burden of disease and costs to the health system are very high in Peru. Higher cigarette taxes could have substantial health and economic benefits for the country.


Revista Peruana de Medicina Experimental y Salud Pública | 2016

Salud oral del adulto mayor: acceso, desafíos y oportunidades para la salud pública peruana

Diego Azañedo; Deysi Díaz-Seijas; Akram Hernández-Vásquez

1 Instituto de Investigación. Universidad Católica los Ángeles de Chimbote. Chimbote, Perú. 2 Instituto Nacional Cardiovascular Carlos Alberto Peschiera Carrillo INCOR, EsSalud. Lima, Perú. 3 Universidad de Buenos Aires. Buenos Aires, Argentina. a Cirujano dentista; b licenciada en Enfermería, especialista en Cuidados Intensivos; c médico cirujano, magíster en Gestión y Políticas Públicas. Recibido: 12/02/2016 Aprobado: 09/03/2016

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Deysi Díaz-Seijas

National University of San Marcos

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Marilina Santero

University of Buenos Aires

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Stalin Vilcarromero

Naval Medical Research Center

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Andrea Alcaraz

National Scientific and Technical Research Council

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A Bardach

National Scientific and Technical Research Council

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F. Augustovski

National Scientific and Technical Research Council

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