Alain Cotté

Non photochemical synthesis of condensed cyclobutenes. Syntheses of the cis-anti-cis-tricyclo [5.3.0.02,6] decane skeleton

Abstract The way to the cis-anti-cis tricyclo [5.3.0.0 2,6 ] decane skeleton which represents an important substructure of natural sesquiterpenes(bourbonenes) and natural diterpenes(spatanes) is described starting from functionalized bicyclo [3.2.0] heptanic derivatives.

Total synthesis of (±) stoechospermol

Abstract The total synthesis of (±) stoechospermol starting from 7-methylbicyclo [3.2.0] hept-2-en-6-one 2 is described.

Synthesis of polyquinanes via bicyclo [2.1.0] pentane intermediates. An easy access to optically pure diquinane alcohols of known absolute configuration.

Abstract The resolution of the cyclobutenic ester 1 using chiral lactols is described. After a stereospecific reaction sequence (cyclopropanation followed by an acidic solvolysis), the enantiomerically pure diquinanes 10 are obtained.