Alejandro Grinberg

Reactive Hemophagocytic Syndrome Associated With Disseminated Strongyloidiasis

ABSTRACT: The reactive hemophagocytic syndrome is a condition characterized by systemic proliferation of benign hemophagocytic histiocytes, fever, cytopenia, abnormal liver function, and frequently coagulopathy and hepatospleno- megaly. Its occurrence has been documented in association with viral, bacterial, fungal, and parasitic infections; a wide spectrum of malignant neoplasms; some miscellaneous disorders; and Phenytoin. Disseminated strongyloidiasis is reported in a patient with systemic lupus erythematosus treated with corticosteroids in whom a reactive hemophagocytic syndrome developed and who finally died. This reactive hemophagocytic syndrome is reported for the first time in strongyloidiasis and may not have been recognized in former reports.