Alena Havelková

Seven-day/24-h ambulatory blood pressure monitoring: night-time blood pressure and dipping status.

Seven-day/24-h ambulatory blood pressure monitoring: night-time blood pressure and dipping status.

PS 02-66 AMBULATORY BLOOD PRESSURE MONITORING ANALYSED FROM SEVEN DAY/ 24 HOUR RECORD

Objective: From the database of 348 patients with essential hypertension, we analyzed the seven day mean blood pressure from seven day/ 24 hour ambulatory monitoring and we studied the relationship between age and circadian blood pressure variation. Design and Method: Three hundred and forty-eight patients in the age from 20 to 82 years, were ambulatory monitored for seven-day/24 hour. Medical instruments (A&D, Japan) were used for ambulatory blood pressure monitoring (oscillation method, 30-minute interval between measurements). We calculated mean values of seven day/24 hour monitoring for systolic and diastolic blood pressure (M) and mean value of amplitude ( of the curve (double amplitude corresponds to the night-day difference) were evaluated double amplitude (2A). Results: Mean values of seven day/24hour systolic and diastolic blood pressure of M (±SD) for the whole group were: SBP was 125 ± 8mmHg, DBP was 76 ± 6 mmHg, HR was 71 ± 6 bpm; of 2A: SBP – 21 ± 7, DBP – 15 ± 5 mmHg, HR – 15 ± 6 bpm. The linear relationship between M of SBP and age (r = 0.34, p< 0.001) and DBP and age (r = 0.39, p<0.001) was found (difference between age 20 and 77 years: SBP – 16 mmHg, DBP-12 mmHg). 2A of SBP and DBP was increasing with age up to 35 years, then the curve remained relatively flat up to 55 years (maximum at 45 years) and then decreased again (difference between 45 and 77 years: SBP was 13mmHg, DBPwas12 mmHg). Heart rate values of M and 2A were age-independent. Conclusions: Seven day /24 hour blood pressure monitoring showed that mean values of seven day/24 hour blood pressure of SBP were increasing with age up to 75 years, night-day difference of SBP and DBP reached the maximum value at 45 years and then decreased.

3D.06: BLOOD PRESSURE VARIABILITY AT REST AND DURING EXERCISE IN HEALTHY MEN: SEVEN DAY AMBULATORY BLOOD PRESSURE MONITORING.

Objective: The aim of the study was to compare 24-hour profile from the 7-day blood pressure monitoring at rest and during exercise. From the seven day ambulatory blood pressure monitoring we compared the blood pressure 24 h profile in the day with exercise (0–24 h) and in the day without exercise (25–48 h after exercise). Design and method: We examined 21 men, healthy subjects, age 29 ± 4.9 years. For exercise training we used bicycle ergometer Kettler, type X7, Germany. The subjects were recruited for seven-day blood pressure monitoring (A and D, Japan). To made comparison among the 24-h profile of blood pressure in the days with exercises (0–24 h) and the days without exercise (25–48 h) we used Bland-Altman statistical method. Results: The 24-hour mean SBP in the day with exercise (119 ± 2.1 mmHg) and in the day without exercise (119 ± 1.7 mmHg) and the 24-hour mean DBP in the day with exercise (69 ± 1.5 mmHg) and in the day without exercise (69 ± 1.5 mmHg) in 21 healthy subject was not different. Comparisons between 7-days mean and 24-hour means SBP in the days with exercise using Bland-Altman plot showed the limits of agreement in the day with exercise (the ± 1.96 SD of the difference in 24-hour means of SBP was 6.85 mmHg and in the days without exercise the limits of the agreement (the ± 1.96 SD of the difference) was 8.59 mmHg. Bland-Altman plot comparisons between 7-days mean and 24-hour means DBP in the days with exercise the limits of the agreement (the ± 1.96 SD of the difference in DBP) was 4.95 mmHg and in the days without exercise (the ± 1.96 SD of the difference in DBP) was 6.06 mmHg. Conclusions: Our results showed large variability of mean 24 h SBP in the days with exercise and also in the days without exercise and also in DBP the variability is similarly large. Bland –Altman plots comparing daily SBP and DBP in days with exercise and without exercise showed that the 24 h means of blood pressure were not affected by exercise, and also the blood pressure variability was not affected.

887 Seven day blood pressure monitoring in patients after myocardial infarction

Objective: The aim of the study was to compare 24-hour course of blood pressure immediately after the cardiovascular exercise training with the values from the following day when the patients after myocardial infarction did not exercise. Method: The group being monitored consisted of 41 patients after myocardial infarction of the age 63 ± 6.3 years and ejection fraction 43 ± 12.3 %. In the course of cardiac rehabilitation (aerobic and resistance training, lasted 60 minutes), the patients were subjected to 7-day ambulatory blood pressure monitoring (AD TM2421 Japan). During 7-day blood pressure monitoring their pharmacotherapy was not interrupted and consisted of ACE inhibitors, betablockers and statins. Results: The mean values of 24-h blood pressure profile (systolic ad diastolic) did not differ between the day with exercises and the day without exercise (120 ± 9 versus 120 ± 8mmHg, 72 ± 8 versus 72 ± 8mmHg). Comparison of hour differences in systolic and diastolic blood pressure indicated that only in the first hour after the exercises training the systolic pressure is lower than in the check course (120+4 mmHg versus 125+3 mmHg, p<0.01). Also in the second hour after the exercises the value is lower, the difference, however, is not statistically significant any more. In the other hours both profiles were not different. We have found no differences in diastolic pressure. Conclusion: The analysis of 24-hour profile of systolic and diastolic blood pressure showed that the exercise training change systolic blood pressure only one hour immediately after the exercises.

Seven-day ambulatory blood pressure monitoring and day andnight blood pressure variability

The paper deals with seven-day ambulatory blood pressure monitoring and day and night blood pressure variability.

TWENTY FOUR-HOUR PROFILE OF BLOOD PRESSURE AFTER 60-MINUTES LASTING CARDIAC EXERCISE TRAINING IN PATIENTS AFTER MYOCARDIAL INFARCTION: PP.14.22

Objective: The aim of the study was to compare 24-hour course of blood pressure immediately after the exercise training with the values from the following day when the patients after myocardial infarction did not exercise. Method: The group being monitored consisted of 23 patients after myocardial infarction of the age 63 ± 6.3 years and ejection fraction 43 ± 12.3 %. In the course of cardiac rehabilitation (aerobic and resistance training, lasted 60 minutes), the patients were subjected to 7-day ambulatory blood pressure monitoring (AD TM2421 Japan). During 7-day blood pressure monitoring their pharmacotherapy was not interrupted and consisted of ACE inhibitors, betablockers and statins. Results: The mean values of 24-h blood pressure profile (systolic ad diastolic) did not differ between the day with exercises and the day without exercise (120 ± 9 versus 120 ± 8mmHg, 72 ± 8 versus 72 ± 8mmHg). Comparison of hour differences in systolic and diastolic blood pressure indicated that only in the first hour after the exercises training the systolic pressure is lower than in the check course (120 + 4 mmHg versus 125 + 3 mmHg, p < 0.01). Also in the second hour after the exercises the value is lower, the difference, however, is not statistically significant any more. In the other hours both profiles were not different. We have found no differences in diastolic pressure. Conclusion: The analysis of 24-hour profile of systolic and diastolic blood pressure showed that the exercise training change systolic blood pressure only one hour immediately after the exercises.