Alessandra Lattanzi

Lanthanides in organic synthesis: Eu+3-catalyzed Michael addition of 1,3- dicarbonyl compounds

EuCl3 proves to be an efficient catalyst for Michael addition of 1,3-dicarbonyl compounds. The employment of Eu+3 chiral complex [Eu(tfc)3] allows the formation of Michael adducts in enantioselective way.

KINETIC RESOLUTION OF RACEMIC SULFOXIDES BY A MODIFIED SHARPLESS PROCEDURE

Abstract Kinetic resolution of racemic sulfoxides is achieved by enantioselective oxidation to sulfones under Sharpless-type conditions.

Asymmetric oxidation with furylhydroperoxides

Abstract Chiral sulfoxides are accessible with very satisfactory enantiomeric excesses through a modified Sharpless procedure, based on the employment of furylhydroperoxides. Racemic hydroperoxides are found to undergo a kinetic resolution in the course of the asymmetric oxidation.

Zeolite-catalyzed oxidation of benzylic and acetylenic alcohols with t-butyl hydroperoxide

4 A molecular sieves catalyze the mild conversion of activated secondary alcohols into the corresponding carbonyl compounds with t-butyl hydroperoxide (TBHP).

An easy approach to butenolides by Horner-Wadsworth-Emmons olefination of α-hydroxy ketones

Abstract By treatment with stabilized lithium phosphonates in the presence of activated 4A molecular sieves, unprotected α-hydroxy ketones 1 undergo a convenient Horner-Wadsworth-Emmons olefination to give directly butenolides 3 as exclusive or predominant products.

Sharpless epoxidation by in situ generation of furylhydroperoxides

Abstract The compatibility of the generation of furylhydroperoxides by a radical chain process with the presence of oxygen acceptors and transition metal catalysts allows the achievement of a modified Sharpless procedure for the epoxidation of allylic alcohols and oxidation of sulphides to sulphoxides.