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Dive into the research topics where Alexander T. Ihler is active.

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Featured researches published by Alexander T. Ihler.


IEEE Journal on Selected Areas in Communications | 2005

Nonparametric belief propagation for self-localization of sensor networks

Alexander T. Ihler; John W. Fisher; Randolph L. Moses; Alan S. Willsky

Automatic self-localization is a critical need for the effective use of ad hoc sensor networks in military or civilian applications. In general, self-localization involves the combination of absolute location information (e.g., from a global positioning system) with relative calibration information (e.g., distance measurements between sensors) over regions of the network. Furthermore, it is generally desirable to distribute the computational burden across the network and minimize the amount of intersensor communication. We demonstrate that the information used for sensor localization is fundamentally local with regard to the network topology and use this observation to reformulate the problem within a graphical model framework. We then present and demonstrate the utility of nonparametric belief propagation (NBP), a recent generalization of particle filtering, for both estimating sensor locations and representing location uncertainties. NBP has the advantage that it is easily implemented in a distributed fashion, admits a wide variety of statistical models, and can represent multimodal uncertainty. Using simulations of small to moderately sized sensor networks, we show that NBP may be made robust to outlier measurement errors by a simple model augmentation, and that judicious message construction can result in better estimates. Furthermore, we provide an analysis of NBPs communications requirements, showing that typically only a few messages per sensor are required, and that even low bit-rate approximations of these messages can be used with little or no performance impact.


knowledge discovery and data mining | 2008

Fast collapsed gibbs sampling for latent dirichlet allocation

Ian Porteous; David Newman; Alexander T. Ihler; Arthur U. Asuncion; Padhraic Smyth; Max Welling

In this paper we introduce a novel collapsed Gibbs sampling method for the widely used latent Dirichlet allocation (LDA) model. Our new method results in significant speedups on real world text corpora. Conventional Gibbs sampling schemes for LDA require O(K) operations per sample where K is the number of topics in the model. Our proposed method draws equivalent samples but requires on average significantly less then K operations per sample. On real-word corpora FastLDA can be as much as 8 times faster than the standard collapsed Gibbs sampler for LDA. No approximations are necessary, and we show that our fast sampling scheme produces exactly the same results as the standard (but slower) sampling scheme. Experiments on four real world data sets demonstrate speedups for a wide range of collection sizes. For the PubMed collection of over 8 million documents with a required computation time of 6 CPU months for LDA, our speedup of 5.7 can save 5 CPU months of computation.


information processing in sensor networks | 2004

Nonparametric belief propagation for self-calibration in sensor networks

Alexander T. Ihler; John W. Fisher; Randolph L. Moses; Alan S. Willsky

Automatic self-calibration of ad-hoc sensor networks is a critical need for their use in military or civilian applications. In general, self-calibration involves the combination of absolute location information (e.g. GPS) with relative calibration information (e.g. time delay or received signal strength between sensors) over regions of the network. Furthermore, it is generally desirable to distribute the computational burden across the network and minimize the amount of inter-sensor communication. We demonstrate that the information used for sensor calibration is fundamentally local with regard to the network topology and use this observation to reformulate the problem within a graphical model framework. We then demonstrate the utility of nonparametric belief propagation (NBP), a recent generalization of particle filtering, for both estimating sensor locations and representing location uncertainties. NBP has the advantage that it is easily implemented in a distributed fashion, admits a wide variety of statistical models, and can represent multi-modal uncertainty. We illustrate the performance of NBP on several example networks while comparing to a previously published nonlinear least squares method.


knowledge discovery and data mining | 2006

Adaptive event detection with time-varying poisson processes

Alexander T. Ihler; Jon Hutchins; Padhraic Smyth

Time-series of count data are generated in many different contexts, such as web access logging, freeway traffic monitoring, and security logs associated with buildings. Since this data measures the aggregated behavior of individual human beings, it typically exhibits a periodicity in time on a number of scales (daily, weekly,etc.) that reflects the rhythms of the underlying human activity and makes the data appear non-homogeneous. At the same time, the data is often corrupted by a number of bursty periods of unusual behavior such as building events, traffic accidents, and so forth. The data mining problem of finding and extracting these anomalous events is made difficult by both of these elements. In this paper we describe a framework for unsupervised learning in this context, based on a time-varying Poisson process model that can also account for anomalous events. We show how the parameters of this model can be learned from count time series using statistical estimation techniques. We demonstrate the utility of this model on two datasets for which we have partial ground truth in the form of known events, one from freeway traffic data and another from building access data, and show that the model performs significantly better than a non-probabilistic, threshold-based technique. We also describe how the model can be used to investigate different degrees of periodicity in the data, including systematic day-of-week and time-of-day effects, and make inferences about the detected events (e.g., popularity or level of attendance). Our experimental results indicate that the proposed time-varying Poisson model provides a robust and accurate framework for adaptively and autonomously learning how to separate unusual bursty events from traces of normal human activity.


IEEE Signal Processing Magazine | 2006

Distributed fusion in sensor networks

Müjdat Çetin; Lei Chen; John W. Fisher; Alexander T. Ihler; Randolph L. Moses; Martin J. Wainwright; Alan S. Willsky

This paper presents an overview of research conducted to bridge the rich field of graphical models with the emerging field of data fusion for sensor networks. Both theoretical issues and prototyping applications are discussed in addition to suggesting new lines of reasoning.


Proceedings of the National Academy of Sciences of the United States of America | 2012

Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis

Mikhail Geyfman; Vivek Kumar; Qiang Liu; Rolando Ruiz; William Gordon; Francisco Espitia; Eric Cam; Sarah E. Millar; Padhraic Smyth; Alexander T. Ihler; Joseph S. Takahashi; Bogi Andersen

The role of the circadian clock in skin and the identity of genes participating in its chronobiology remain largely unknown, leading us to define the circadian transcriptome of mouse skin at two different stages of the hair cycle, telogen and anagen. The circadian transcriptomes of telogen and anagen skin are largely distinct, with the former dominated by genes involved in cell proliferation and metabolism. The expression of many metabolic genes is antiphasic to cell cycle-related genes, the former peaking during the day and the latter at night. Consistently, accumulation of reactive oxygen species, a byproduct of oxidative phosphorylation, and S-phase are antiphasic to each other in telogen skin. Furthermore, the circadian variation in S-phase is controlled by BMAL1 intrinsic to keratinocytes, because keratinocyte-specific deletion of Bmal1 obliterates time-of-day–dependent synchronicity of cell division in the epidermis leading to a constitutively elevated cell proliferation. In agreement with higher cellular susceptibility to UV-induced DNA damage during S-phase, we found that mice are most sensitive to UVB-induced DNA damage in the epidermis at night. Because in the human epidermis maximum numbers of keratinocytes go through S-phase in the late afternoon, we speculate that in humans the circadian clock imposes regulation of epidermal cell proliferation so that skin is at a particularly vulnerable stage during times of maximum UV exposure, thus contributing to the high incidence of human skin cancers.


Communications of The ACM | 2010

Nonparametric belief propagation

Erik B. Sudderth; Alexander T. Ihler; Michael Isard; William T. Freeman; Alan S. Willsky

Continuous quantities are ubiquitous in models of real-world phenomena, but are surprisingly difficult to reason about automatically. Probabilistic graphical models such as Bayesian networks and Markov random fields, and algorithms for approximate inference such as belief propagation (BP), have proven to be powerful tools in a wide range of applications in statistics and artificial intelligence. However, applying these methods to models with continuous variables remains a challenging task. In this work we describe an extension of BP to continuous variable models, generalizing particle filtering, and Gaussian mixture filtering techniques for time series to more complex models. We illustrate the power of the resulting nonparametric BP algorithm via two applications: kinematic tracking of visual motion and distributed localization in sensor networks.


PLOS Genetics | 2009

Circadian clock genes contribute to the regulation of hair follicle cycling.

Kevin K. Lin; Vivek Kumar; Mikhail Geyfman; Darya Chudova; Alexander T. Ihler; Padhraic Smyth; Ralf Paus; Joseph S. Takahashi; Bogi Andersen

Hair follicles undergo recurrent cycling of controlled growth (anagen), regression (catagen), and relative quiescence (telogen) with a defined periodicity. Taking a genomics approach to study gene expression during synchronized mouse hair follicle cycling, we discovered that, in addition to circadian fluctuation, CLOCK–regulated genes are also modulated in phase with the hair growth cycle. During telogen and early anagen, circadian clock genes are prominently expressed in the secondary hair germ, which contains precursor cells for the growing follicle. Analysis of Clock and Bmal1 mutant mice reveals a delay in anagen progression, and the secondary hair germ cells show decreased levels of phosphorylated Rb and lack mitotic cells, suggesting that circadian clock genes regulate anagen progression via their effect on the cell cycle. Consistent with a block at the G1 phase of the cell cycle, we show a significant upregulation of p21 in Bmal1 mutant skin. While circadian clock mechanisms have been implicated in a variety of diurnal biological processes, our findings indicate that circadian clock genes may be utilized to modulate the progression of non-diurnal cyclic processes.


ieee international workshop on computational advances in multi-sensor adaptive processing | 2007

Modeling Count Data from Multiple Sensors: A Building Occupancy Model

Jon Hutchins; Alexander T. Ihler; Padhraic Smyth

Knowledge of the number of people in a building at a given time is crucial for applications such as emergency response. Sensors can be used to gather noisy measurements which when combined, can be used to make inferences about the location, movement and density of people. In this paper we describe a probabilistic model for predicting the occupancy of a building using networks of people-counting sensors. This model provides robust predictions given typical sensor noise as well as missing and corrupted data from malfunctioning sensors. We experimentally validate the model by comparing it to a baseline method using real data from a network of optical counting sensors in a campus building.


ACM Transactions on Knowledge Discovery From Data | 2007

Learning to detect events with Markov-modulated poisson processes

Alexander T. Ihler; Jon Hutchins; Padhraic Smyth

Time-series of count data occur in many different contexts, including Internet navigation logs, freeway traffic monitoring, and security logs associated with buildings. In this article we describe a framework for detecting anomalous events in such data using an unsupervised learning approach. Normal periodic behavior is modeled via a time-varying Poisson process model, which in turn is modulated by a hidden Markov process that accounts for bursty events. We outline a Bayesian framework for learning the parameters of this model from count time-series. Two large real-world datasets of time-series counts are used as testbeds to validate the approach, consisting of freeway traffic data and logs of people entering and exiting a building. We show that the proposed model is significantly more accurate at detecting known events than a more traditional threshold-based technique. We also describe how the model can be used to investigate different degrees of periodicity in the data, including systematic day-of-week and time-of-day effects, and to make inferences about different aspects of events such as number of vehicles or people involved. The results indicate that the Markov-modulated Poisson framework provides a robust and accurate framework for adaptively and autonomously learning how to separate unusual bursty events from traces of normal human activity.

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Padhraic Smyth

University of California

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John W. Fisher

Massachusetts Institute of Technology

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Rina Dechter

University of California

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Bogi Andersen

University of California

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Julian Yarkony

University of California

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Ramgopal R. Mettu

University of Massachusetts Amherst

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