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Alexandre Gross

Aventis Pharma

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Publication

Featured researches published by Alexandre Gross.

Tetrahedron Letters | 2001

A stereocontrolled approach to substituted piperidones and piperidines: flavopiridol D-ring analogs

Alexandre Gross; David R. Borcherding; Dirk Friedrich; Jeffrey S. Sabol

Abstract A stereocontrolled approach to substituted piperidones and piperidines is presented, and their utility as intermediates for the synthesis of flavopiridol D-ring analogs is described.

Bioorganic & Medicinal Chemistry Letters | 2005

Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists.

Gregory H. Merriman; Liang Ma; Patrick Wai-Kwok Shum; Daniel G. Mcgarry; Frank Volz; Jeffrey S. Sabol; Alexandre Gross; Zhicheng Zhao; David Rampe; Lin Wang; Friederike Wirtz-Brugger; Bruce A. Harris; Douglas Macdonald

Archive | 2004

Heterocyclic compounds as p2x7 ion channel blockers

Patrick Wai-Kwok Shum; Alexandre Gross; Liang Ma; Daniel G. Mcgarry; Gregory H. Merriman; David Rampe; Garth E. Ringheim; Jeffrey S. Sabol; Francis A. Volz

Archive | 2004

1- (2h-pyrazol -3-yl) -3yl) {4-`1- (benzoyl) -piperidin-4-ylmethyl!-phenyl}-urea derivatives and related compounds as inhbitors of p38 kinase and/or tnf inhibitors for the treatment of imflammations

David R. Borcherding; Alexandre Gross; Patrick Wai-Kwok Shum; Nicole Willard; Brian S. Freed

Archive | 2004

4,5-dihydro-imidazole as p2x7 ion channel blockers

Patrick Wai-Kwok Shum; Alexandre Gross; Liang Ma; Daniel G. Mcgarry; Gregory H. Merriman; David Rampe; Garth E. Ringheim; Jeffrey S. Sabol; Francis A. Volz

Archive | 2003

3-substituted amino-1h-indole-2-carboxylic acid and 3-substituted amino-benzo' b! thiophene-2-carboxylic acid derivatives as interieukin-4 gene expression inhibitors

Gregory H. Merriman; Philip M. Weintraub; Jeffrey S. Sabol; Ramalinga M. Dharanipragada; Nicholas J. Hrib; John G. Jurcak; Alexandre Gross; Brian Whiteley; Kwon Yon Musick; Joseph T. Klein

Archive | 2003

Indole derivatives as interleukin-4 gene expression inhibitors

Gregory H. Merriman; Philip M. Weintraub; Jeffrey S. Sabol; Ramalinga M. Dharanipragada; Nicholas J. Hrib; John G. Jurcak; Alexandre Gross; Brian Whiteley; Kwon Yon Musick; Joseph T. Klein

Archive | 2010

1-(2H-PYRAZOL-3-YL)-3- -UREA DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF P38 KINASE AND/OR TNF INHIBITORS FOR THE TREATMENT OF INFLAMMATIONS

Borcherding David R; Alexandre Gross; Wai-Kwok Shum Patrick; Nicole Willard; Freed Brian S

Archive | 2005

Pyrazoles as inhibitors of tumor necrosis factor

David R. Borcherding; Alexandre Gross; Patrick Wai-Kwok Shum; Nicole Willard; Brian S. Freed

Archive | 2004

PIRAZOLES COMO INHIBIDORES DE FACTOR DE NECROSIS TUMORAL

David R. Borcherding; Alexandre Gross; Patrick Wai-Kwok Shum; Nicole Willard; Brian S. Freed

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Collaboration

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Patrick Wai-Kwok Shum

Aventis Pharma

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Gregory H. Merriman

Aventis Pharma

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Jeffrey S. Sabol

Aventis Pharma

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Nicole Willard

Aventis Pharma

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Brian S. Freed

Aventis Pharma

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Brian Whiteley

Aventis Pharma

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Daniel G. Mcgarry

Rhône-Poulenc

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David Rampe

Aventis Pharma

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Liang Ma

Aventis Pharma

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Ramalinga M. Dharanipragada

Aventis Pharma

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