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Alexei Toutchkine

Scripps Research Institute

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Publication

Featured researches published by Alexei Toutchkine.

Current Opinion in Cell Biology | 2002

Live-cell fluorescent biosensors for activated signaling proteins

Klaus M. Hahn; Alexei Toutchkine

A new generation of live-cell fluorescent biosensors enables us to go beyond visualization of protein movements, to quantify the dynamics of many different protein activities. Alternate approaches can report post-translational modifications, ligand interactions and conformational changes, revealing how the location and subtle timing of protein activity controls cell behavior.

Journal of the American Chemical Society | 2003

Solvent-sensitive dyes to report protein conformational changes in living cells

Alexei Toutchkine; Vadim S. Kraynov; Klaus M. Hahn

ChemPhysChem | 2003

A Theoretical Study of the UV/Visible Absorption and Emission Solvatochromic Properties of Solvent-Sensitive Dyes

Wen Ge Han; Tiqing Liu; Fahmi Himo; Alexei Toutchkine; Donald Bashford; Klaus M. Hahn; Louis Noodleman

Journal of Physical Chemistry B | 2004

Single-Molecule Study of Protein−Protein Interaction Dynamics in a Cell Signaling System

Xin Tan; Perihan Nalbant; Alexei Toutchkine; Dehong Hu; Erich R. Vorpagel; Klaus M. Hahn; H. Peter Lu

Journal of Physical Chemistry A | 2004

Density Functional Vertical Self-Consistent Reaction Field Theory for Solvatochromism Studies of Solvent-Sensitive Dyes

Tiqing Liu; Wen Ge Han; Fahmi Himo; G. Matthias Ullmann; Donald Bashford; Alexei Toutchkine; Klaus M. Hahn; Louis Noodleman

Archive | 2005

Labeled peptides, proteins and antibodies and processes and intermediates useful for their preparation

Klaus M. Hahn; Alexei Toutchkine; Rajeev Muthyala; Vadim S. Kraynov; Steven J. Bark; Dennis R. Burton; Chester E. Chamberlain

Bioconjugate Chemistry | 2002

Facile synthesis of thiol-reactive Cy3 and Cy5 derivatives with enhanced water solubility.

Alexei Toutchkine; Perihan Nalbant; Klaus M. Hahn

Journal of the American Chemical Society | 2001

Substituent-dictated partitioning of intermediates on the sulfide singlet oxygen reaction surface. A new mechanism for oxidative C--S bond cleavage in alpha-hydroperoxy sulfides.

Alexei Toutchkine; David Aebisher; Edward L. Clennan

Archive | 2005

Live cell biosensors

Klaus M. Hahn; Alexei Toutchkine

Archive | 2007

Sulfhydryl-reactive, water soluble dyes

Klaus M. Hahn; Alexei Toutchkine; Dmitriy Gremyachinskiy

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Klaus M. Hahn

Scripps Research Institute

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Dmitriy Gremyachinskiy

University of North Carolina at Chapel Hill

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Donald Bashford

St. Jude Children's Research Hospital

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Louis Noodleman

Scripps Research Institute

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Tiqing Liu

Scripps Research Institute

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Vadim S. Kraynov

Scripps Research Institute

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Wen Ge Han

Scripps Research Institute

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Perihan Nalbant

University of Duisburg-Essen

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Fahmi Himo

Stockholm University

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Chester E. Chamberlain

Scripps Research Institute

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