Ali Yanık

Ultrasonographic measurement of cervical length in predicting mode of delivery after oxytocin induction.

This study was conducted to explore the value of transvaginal ultrasonographic cervical length measurement, in addition to gestational age, maternal age, parity, Bishop score, and weight of the newborn, in predicting the mode of delivery in pregnancies in which labor is induced with oxytocin at or beyond the 40th gestational week. A total of 73 pregnancies at 40 to 42 weeks of gestation were included. After labor was induced, 29 women delivered vaginally and 44 underwent cesarean section. These groups were compared with respect to possible predictive parameters of delivery outcomes. Studentt test, Pearson’s correlation analysis, and logistic regression analysis were used for statistical evaluation. Mean preinduction cervical length was 26.8±9.9 mm in the vaginal delivery group and 34.2±8.1 mm in the cesarean section group (P < .05). Mean maternal age, parity, and Bishop score were significantly higher and mean weight of the newborn was significantly lower in the vaginal delivery group. Cervical length measurements showed a significant negative correlation with Bishop scores (r=−.584;P < .05). Logistic regression analysis revealed that Bishop score (likelihood ratio=.472; 95% confidence interval=.338–.658;P < .05) and weight of the newborn (likelihood ratio=1.002; 95% confidence interval=1 .00007–1.003;P < .05) were significant independent predictors of the route of delivery. According to the results of this study, maternal age, parity, Bishop score, cervical length, and weight of the newborn all might affect the mode of delivery after labor induction. Bishop score, although a subjective measure, must be considered an important component of preinduction evaluation.

The availability of vaginal hysterectomy in benign gynecologic diseases : A prospective, non-randomized trial

Objective:  To determine whether vaginal hysterectomy can be performed in patients with benign gynecologic diseases regardless of uterine size, uterine mobility and previous pelvic surgery and to compare with abdominal hysterectomy.

Primary Sjögren’s Syndrome Adversely Affects the Female Sexual Function Assessed by the Female Sexual Function Index: A Case-Control Study

Objectives This study aims to evaluate the sexual function of females with primary Sjögrens syndrome (pSS) in comparison to healthy females by using the Female Sexual Function Index (FSFI). Patients and methods This case-control study included 31 female patients (mean age 46.0±10.2 years; range 30 to 68 years) with pSS and 27 healthy females (mean age 44.2±8.5 years; range 30 to 55 years) as control group. The sexual function of the participants was assessed by 19-item FSFI. Results Mean duration of pSS in the patient group was 35.9 months (range 3 to 264 months). Significantly higher number of pSS patients reported positive history for vaginal infection compared to controls (n=26, 83.9% vs. n=7, 25.9%, respectively; p<0.001) without any difference in endocervical culture result. Cervical smear assessment revealed more inflammation and atrophy in patient group compared to control group (p=0.001). Mean FSFI total score was significantly lower in patient group than control group (18.9±9.9 vs. 25.1±5.1, respectively; p=0.004). Similarly, five out of six domains of FSFI -arousal, lubrication, orgasm, satisfaction, and pain- were significantly lower in patient group. FSFI total and subscale scores, except for pain, were found to be negatively correlated with duration of pSS. Conclusion The pSS causes sexual dysfunction in female patients. Furthermore, as disease duration increases, female sexual function decreases. Clinical management of female patients with pSS should cover the assessment of their sexual functionality and taking the necessary precautions to maintain satisfactory quality of life and treatment outcome.

The Significance of Neutrophil-Lymphocyte Ratio and Mean Corpuscular Volume in Diagnosis of Preeclampsia

OBJECTIVE: The aim of this study is to evaluate the diagnostic values of neutrophil to lymphocyte ratio (NLR) and mean corpuscular volume (MCV) in patients with preeclampsia. STUDY DESIGN: A retrospective analysis of patients with documented preeclampsia and uncomplicated pregnancy was carried out. Two hundred and twelve women with preeclampsia, and 58 healthy pregnant women as controls were included in the study. NLR and MCV values were calculated from complete blood count analysis. RESULTS: White blood cell, NLR and MCV values were higher in the preeclamptic patients than those of the controls. The study groups had similar features with regard to the maternal age, gravidity, parity, and mode of delivery. Gestational age, newborn weight, and Apgar scores of the newborns were found lower in the preeclampsia group. CONCLUSION: NLR may be helpful in the differential diagnosis of preeclampsia. Large-scale prospective studies with categorized study groups according to the severity of preeclampsia need to be performed to determine the optimal NLR values useful for the assessment of severity of preeclampsia.

Comparation of clinic and demographic specialities of benign and malign pathologies of endometrium

Aim. The objective of this study is to compare clinical and demographic data of benign and malign pathologies of endometrium and to describe risc factors for endomatrial carcinoma. Method. Eighty-eight patients which was hysterectomised in our clinic between 2006 and 2010 was included. Twenty eight of these has the diagnosis as ‘proliferative endometrium’, twenty nine as ‘hyperplasia of endometrium’, thirty-one as ‘endometrioid type of endometrial carcinoma’. Data were collected from patient files retrospectively. Results. Pregnancy and parity rate, presence of diabetes mellitus and smoking were not altered for groups. Endometrial thickness and presence of hypertension were significantly higher for carcinoma group. Endometrial carcinoma patients were generally postmenauposal and had younger menarche age. Discussion. Advanced age, early menarche, increased endometrial thickness, hypertension and postmenapouse are risk factors for endometrial carcinoma.

The evaluation of our intraoperative consultation results in ovarian lesions for five years

Aim. Intraoperative consultation has an important role in the diagnosis and treatment of ovarian masses. During surgery, the correct classification as benign, borderline or malignant (primary/metastatic) provides to appropriate surgical staging. This retrospective study was undertaken to determine the accuracy of intraoperative consultation results in ovarian lesions and to review the diagnostic problems that may be causing the error. Method. Between January 2007December 2011, the diagnoses of 246 intraoperative consultations applied to the ovarian lesions were examined retrospectively. Twenty-five out of 246 of these sections belonged to the same patient. Frozen section diagnoses were compared with paraffin section diagnoses. Results. The mean age of the patients was 46.7±16 (17-87). There was an agreement in diagnosis between frozen and paraffin section in 96.3%. The sensitivity of malignant cases, 96.9%, specificity was 100%. The positive predictive value of malignant cases was 100%, negative predictive value of benign cases was 100%. In series had no false positive, false negative rate was 6%. Diagnosis had been deferred in 2.4% of the cases. The incompatible diagnoses caused by limited sampling during intraoperative consultation. There were metastatic tumors in 3.7%, mixed type tumors in 2%. Conclusion. The concensus between the gynecologist and the pathologist is very important in intraoperative consultation process. In our series, the sensitivity and specificity of the frozen application in ovarian lesions were high, and the our results are reliable. It was concluded that increasing the number of samples for especially in large tumors will decrease the false-negative rate.