Alireza Khorshidi

Sulfuric acid functionalized MCM-41 coated on magnetite nanoparticles as a recyclable core–shell solid acid catalyst for three-component condensation of indoles, aldehydes and thiols

Magnetite nanoparticles were used as a core for –OSO3H functionalized mesoporous MCM-41 shell to provide a core–shell solid acid catalyst (Fe3O4@MCM-41-OSO3H). The catalyst was characterized by transmission electron microscopy (TEM), infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and a vibrating sample magnetometer (VSM). The obtained nano-magnetic catalyst was used in the three-component reaction of indoles, aldehydes and thiols to furnish the desired 3-[(aryl)(arylthio)methyl]-1H-indoles in good yields under very mild reaction conditions. The unique feature of the reaction was the ease of work-up and catalyst recovery. The recovered catalyst maintained catalytic activity for five successive runs.

Ruthenium-catalyzed efficient routes to oxindole derivatives

Ruthenium-catalyzed preparation of oxindoles from one-pot trimerization of indoles under oxidative conditions and from electrophilic substitution reaction of indoles with isatins or isatin-derived imines under very mild reaction conditions is reported.

Facile and Efficient Method for the Synthesis of 14-Substituted-14-H-dibenzo[a,j]xanthenes Catalyzed by Ruthenium Chloride Hydrate as a Homogeneous Catalyst

Abstract Synthesis of dibenzoxanthenes through condensation of β-naphthol with various aromatic and aliphatic aldehydes in ethanol as an ecofriendly solvent using RuIII as catalyst is reported.

Diastereoselective Ruthenium-Catalyzed Michael Addition of Indoles to Hormone Steroids: An Efficient Route to New Indole Derivatives

Diastereoselective conjugate 1,4-addition of indoles to α,β-unsaturated carbonyl compounds (hormone steroids) using Ru(III) as catalyst is reported. It was found that RuCl3·nH2O catalyzes the Michael addition of indoles to hormone steroids, providing new 3-alkylated derivatives in good to excellent yields.

Ultrasound assisted, ruthenium-exchanged FAU-Y zeolite catalyzed alkylation of indoles with epoxides under solvent free conditions

Ruthenium-exchanged FAU-Y zeolite (RuY) was used as a recyclable catalyst for regioselective ring-opening of epoxides with indoles under irradiation of sonic waves. It was found that a solvent free process, under the above mentioned conditions provides good yields of the desired 3-alkylated indole derivatives.

Efficient synthesis of 3,3′-bisindoles catalyzed by Fe3O4@MCM-48-OSO3H magnetic core-shell nanoparticles

Abstract Magnetite nanoparticles coated with sulfuric acid-functionalized mesoporous MCM-48 were synthesized and used as a catalyst in three-component domino reactions of indoles, arylglyoxal monohydrates and N -arylenaminones to furnish the desired 3,3′-bisindoles by formation of two C–C and one C–N bonds in a smooth cascade with good yields under mild reaction conditions. The catalyst was recovered easily and maintained activity in successive runs.

Efficient one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones catalyzed by a new heterogeneous catalyst based on Co-functionalized Na+-montmorillonite

In the present study, we report a simple, facile and efficient solvent-free protocol for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones by the three component condensation of aldehyde, ethyl acetoacetate and urea through using Co@imine-Na+-MMT as a new, environmentally friendly and reusable heterogeneous catalyst. The structure of the synthesized catalyst was characterized by various techniques, including IR, SEM, TGA, EDX, AAs, DR-UV-vis and XRD analyses. Green reaction conditions, high quantitative yields and the easy isolation of products, easy separation and recovery of the catalyst and short reaction times are some of the advantages of our procedure.

[Fe(bipy)Cl4][bipy.H] hosted by Al-MCM-41: an efficient dibenzo[b,f][1,4]oxazepine (CR) decontamination nano-reactor

Encapsulation of [Fe(bipy)Cl4][bipy.H] (1) (where bipy is 2,2′-bipyridine) in the Al-MCM-41 molecular sieve by using a “ship in a bottle synthesis” approach was achieved and the product characterized by X-ray diffraction, FTIR, DRS, TG, EDS and BET analysis. Encapsulation of the complex into the channels of Al-MCM-41, did not affect the morphology of the host as is evident from SEM and TEM micrographs. The obtained nanocatalyst in combination with K2S2O8 as the oxidant, was successfully used in selective catalytic conversion of dibenzo[b,f][1,4]oxazepine (CR, riot control agent) to dibenzo[b,f][1,4]oxazepin-11(10H)-one as a potential decontamination route. Good selectivity was also obtained toward formation of benzil in the oxidation of trans-stilbene.

Immobilization of laccase on modified Fe 3 O 4 @SiO 2 @Kit-6 magnetite nanoparticles for enhanced delignification of olive pomace bio-waste

Lignocellulose is considered a major source for the production of valuable chemicals. Efficient degradation of lignin as the natural carrier of the lignocellulosic biomass represents a key limiting factor in biomass digestibility. Recently, biological delignification methods have been promoted as sustainable and environmentally friendly alternatives to the traditional technologies. In this study, porous nanocomposite of Fe3O4@SiO2@KIT-6 with magnetic properties was synthesized. The immobilized laccase supported on nanocomposite with enhanced stability in a hydrophobic ionic liquid has been developed for both olive pomace delignification and degradation of phenolic extracts from the pomace. After 6h incubation, the degradation rate of lignin and phenol by the immobilized laccase was estimated to be 77.3% and 76.5%, respectively. The immobilized laccase retained 70% of its initial degradation ability after 11 successive batch treatments of olive pomace. Furthermore, the immobilized laccase retained >70% of its initial activity after 21days of storage at room temperature. The obtained results indicated that the immobilized laccase on magnetic mesoporous support together with (1-Butyl-3-methylimidazolium hexafluorophosphate) ([Bmim][PF6]) could potentially provide a promising procedure for an improved enzymatic degradation of lignin and phenol in the related industries.

Application of trans-[ZrO(curcumin)2(H2O)]·H2O in coloration of cotton fibers

A novel six-coordinate complex of Zr(IV) with curcumin ligand was synthesized and characterized by thermogravimetric analysis, elemental analysis and spectroscopic techniques. 1HNMR and 13CNMR spectra showed that two curcumin ligands behave as a bidentate monobasic ligand and occupy trans- positions, while two other remaining coordination sites of zirconium are occupied by O and H2O. The complex was screened for antibacterial activity and showed no inhibitory effect against Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Salmonella enteritidis. Eventually it was found that the complex can be used as a non-toxic, stable and exotic orange dye in coloration of cotton fibers.