Allan C. Barnes

Sterilization by means of peritoneoscopic tubal fulguration.

The sterilization procedure of peritoneoscopic tubal fulguation is described. With the patient in the Trendelenburg position the peritoneoscope is inserted into the peritoneal cavity through the vagina. The Fallopian tube is grasped near the cornu with biopsy forcep s and the fulgurating current applied until 1 cm of tube is blanched. This procedure is repeated 3-5 cm distally and then in the opposite tube. The patient remains in the hospital 12-18 hours. 6 weeks post operative gross examination shows marked fibrosis of the tubes which contract to the caliber of a fine cord at each point of treatment. Microscopic examination shows destruction of the endosalpinx with marked hyaline fibrosis of the entire tube in that area. The procedure is considered relatively safe. In cases involving perforation immediate laparotomy has repaired the damage. Further study will show the effectiveness of this method.

The extragenital effects of diethylstilbestrol

Abstract During the past year, 100 patients receiving diethylstilbestrol for therapeutic reasons have been carefully observed and studied. All tests were controlled by performing them both before and after treatment. The observations reported relate to the effects of this drug on systems other than the reproductive organs. In general these extragenital effects duplicate those that have been found with the natural estrogens, and while many of these observations are of interest and invite further study, none of them can in any way be considered as representing toxic manifestations of diethylstilbestrol.