Allen Fred Goldberg

Marginal microleakage—an in vivo assessment

Bilaterally paired mandibular teeth scheduled for extraction were chosen for in vivo and in vitro studies of marginal leakage. Decided contrast in test results indicates that marginal microleakage should be determined in vivo. Animal and human tests both show that the removal of a tooth from its organism is decisive in studies of marginal leakage around dental restorations. It is suggested that more accurate functional marginal leakage determinations result from in vivo tests.

Local anesthetic sensitivity. Report of a case.

Abstract A patient with a history of sensitivity to local anesthetic agents may also be sensitive to the preservative commonly used in these solutions. The distinction between the two must be kept in mind if patients are to be treated rationally.

The effect of pulpal tissues on microleakage around dental restorations

Abstract The testing of marginal microleakage should be done under rigidly defined and controlled conditions. While marked differences in results can be shown in various testing conditions, it is becoming apparent that standard conditions are not easily established.

Microleakage around Silver Alloy Restorations in a Biological Model

Microleakage around dental restorations traditionally has been determined in an in vitro system. However, it has not been established that marginal penetration would not be affected by removal of the tooth from the organism, which would eliminate the pulpal hydrostatic pressure and the effect of plaque on the osmotic gradient across the dentin tubules. The in vivo marginal penetration therefore was studied in a biological model to evaluate the present technics for in vitro determination of marginal leakage. Golden Syrian hamsters of the same substrain, purchased from the same source,* were used in groups of 24. From the time of acquisition until they were killed, the hamsters were maintained on a commercial rationt and tap water ad libitum. At an age of about 4 weeks, the hamsters were anesthetized with a 5% solution of sodium pentobarbital, 35 to 40 mg/kg of body weight, given intraperitoneally. Class V cavity preparations in 191 molars were made in the palatal aspect by using a cord-driven dental engine, small dental burs, and hand instruments modified for miniature cavity preparations. Silver alloy restorative material, prepared as for clinical use, was placed in the molars without bases or cavity liners. Four weeks after placement of the restorations, the hamsters were anesthetized and the