Alper Tunga Derin

Cutaneous rhinosporidiosis presents with recurrent nasal philtrum mass in southern Turkey.

We report a case of cutaneous rhinosporidiosis localized in the nasal philtrum. The patients complaints started 3 months prior to being seen in our clinics. Ear, nose, and throat examination showed the presence of a polypoid lesion filling the right nostril. Complete surgical resection of the polypoid lesion provided a temporary relief as the patient developed the same lesion atin 6 weeks post‐operation. The appearance and the recurrence pattern have led us to determine whether this lesion was rhinosporidiosis. Histopathological examination confirmed rhinosporidiosis. Finally, we performed complete resection followed by cauterization of the base of the mass. The infection has been reported in hot, tropical climates, and endemic zones of India and Sri Lanka. To our knowledge there is no reported case of rhinosporidiosis from southern Turkey within the subtropical Mediterranean climatic area.

The place of hyperbaric oxygen therapy and ozone therapy in sudden hearing loss

INTRODUCTION It is difficult to evaluate the effect of drugs clinically used for idiopathic sudden sensorineural hearing loss, mainly because its underlying mechanism remains unknown. OBJECTIVE This study assessed the efficacy of hyperbaric oxygen therapy or ozone therapy in the treatment of idiopathic sudden sensorineural hearing loss, when either therapy was included with steroid treatment. METHODS A retrospective analysis examined 106 patients with idiopathic sudden sensorineural hearing loss seen between January 2010 and June 2012. Those with an identified etiology were excluded. The patients were divided into three treatment groups: oral steroid only (n=65), oral steroid+hyperbaric oxygen (n=26), and oral steroid+ozone (n=17). Treatment success was assessed using Siegel criteria and mean gains using pre- and post-treatment audiograms. RESULTS The highest response rate to treatment was observed in the oral steroid+ozone therapy group (82.4%), followed by the oral steroid+hyperbaric oxygen (61.5%), and oral steroid groups (50.8%). There were no significant differences in the response to treatment between the oral steroid and oral steroid+hyperbaric oxygen groups (p<0.355). The oral steroid+ozone group showed a significantly higher response rate to treatment than the oral steroid group (p=0.019). There were no significant differences between the oral steroid+hyperbaric oxygen and oral steroid+ozone groups (p=0.146). CONCLUSION The efficiency of steroid treatment in patients with severe hearing loss was low. It was statistically ascertained that adding hyperbaric oxygen or ozone therapy to the treatment contributed significantly to treatment success.

Intraoperative assessment of laryngeal malignancy using elastic light single‐scattering spectroscopy: A pilot study

The elastic light single‐scattering spectroscopy (ELSSS) system is a new tool for the real‐time diagnosis of cancerous lesions. In the current study, we have employed ELSSS to investigate its ability in differentiation between normal and cancerous larynx tissues ex vivo.

Primary extraskeletal Ewing's sarcoma of the maxillary sinus☆

Ewing’s sarcoma was identified by James Ewing in 1921 as a perivascular endothelial tumor. Since the 1980s, it has been believed that this tumor originates from mesenchymal, myeloid, or primitive multipotential cells. Although it mostly originates from bones of lower extremities, it can also arise from soft tissues such as paravertebral region. These small round cell tumors have been termed Ewing’s Sarcoma (ES)/Peripheral Primitive Neuroectodermal Tumor (PNET) and include ES of the bone, extraskeletal ES, PNET and Askin’s tumor. Extraskeletal ES rarely occurs in the head and neck localization, account for only 1--4% of all ES, and usually prefers mandibula. However, there are few reports in the literature of ES arising from maxillary sinuses. The gender distribution is equal and nearly half of the patients in age between 10 and 20 years old, while 70% are under the age of 20. The patients usually presented with painless swelling and symptoms such as anemia, leukocytosis, weight loss, nasal congestion (based on the location), vision loss,

Mucoepidermoid Carcinoma of Hard Palate in a Pediatric Case

Salivary gland neoplasms are rare in childhood. Only 1 to5.5% of minor salivary gland tumours occur in children and adolescents. The most common malignant minor salivary gland tumours are mucoepidermoid carcinomas (MECs). Herein, we present a rare case of mucoepidermoid carcinoma occuring in the hard palate. Presentation of Case: A 12-year-old boy visited our hospital with a swelling and ulceration of the right hard palate. Clinical examination revealed a localized mucosal nodule of the right posterior hard palate, measuring 1*1 cm. Biopsy was performed. The tumour was diagnosed as a low grade MEC. Wide excision was performed. The patient didn’t need another therapy. During 15-month follow-up, the patient showed no evidence of local tumour recurrence or metastasis. Discussion: Mucoepidermoid carcinoma occurring in the oral cavity is extremly rare. These tumours are usually presenting as a painless, reddish-purple nodule. Biopsy is necessery for definitive diagnosis. Histologically, MECs are divided into low, intermediate and high grade subtypes. Differantial diagnosis of palatal tumours in children include pleomorphic adenoma, benign or malignant mesenchymal tumours, and less commonly giant cell granuloma. A wide local excision with safe free margins is the operative procedure for low-grade MECs.

Second Case Report of Myxofibrosarcoma of Larynx

A 47 year-old woman admitted to the hospital with progressive hoarseness. On the physical examination of larynx, a 2.5 cm mass was detected on the left arytenoid area. The tumor was totally excised and histopathologic diagnosis was consisted with myxofibrosarcoma of intermediate grade. Myxofibrosarcoma is common soft tissue sarcoma mainly occur in the extremities. Head and neck region is seldom becoming a host for soft tissue sarcomas including myxofibrosarcoma. Here in, we present the second case of laryngeal MFS with its clinicopathological features, differential diagnosis, treatment modalities and prognostic factors with the review of the literature.

Multilocular Cervical ThymicCyst: Rare Cervical Lesion shouldkept in Mind in DifferentialDiagnosis of Pediatric CervicalMasses

Multilocular Cervical Thymic Cyst: Rare Cervical Lesion should kept in Mind in Differential Diagnosis of Pediatric Cervical Masses Congenital anomalies are the most common causes of benign cystic neck masses during the childhood. Cervical thymic cyst is a rare and unique form of cystic neck mass which is usually seen in the first decade of life. Preoperative diagnosis of cervical thymic cysts is challenging due to the rarity and insignificant findings. A seven-year-old-boy presented to hospital with the complaint of progressive swelling on the right side of the neck over a year. Radiologically, magnetic resonance imaging (MRI) revealed a 95 × 37 × 30 mm in size cystic mass located at the right side, anterior of SCM which was related with the carotid sheath. Surgical resection was performed. In the childhood, the thymic cyst comprises less than 1% of the cervical cystic lesions. Rarely may they show malignant transformation. Unilocular thymic cysts are usually congenital and are thought to arise from cystic dilatation of branchial pouch remnants, whereas multilocular thymic cysts are considered to be acquired reactive lesions. Finally, cervical thymic cyst is very rare benign cystic neck mass during the childhood. However, it should be kept in mind in differential diagnosis in case of asymptomatic patients who are between the ages of 2-13 and total surgical resection should be performed because of malignant transformation potential.