Álvaro Abarzúa

Eosinophilic annular erythema in childhood - Case report

Eosinophilic annular erythema is a rare, benign, recurrent disease, clinically characterized by persistent, annular, erythematous lesions, revealing histopathologically perivascular infiltrates with abundant eosinophils. This report describes an unusual case of eosinophilic annular erythema in a 3-year-old female, requiring sustained doses of hydroxychloroquine to be adequately controlled.

Reflectance confocal microscopy in the evaluation of targetoid haemosiderotic haemangioma apropos two cases.

Cristi an Navarrete-Dechent, Rodrigo Schwartz, Salvador Gonz alez, Sergio Gonz alez, Alvaro Abarz ua and Pablo Uribe Melanoma and Skin Cancer Unit, Department of Dermatology, Faculty of Medicine, Pontificia Universidad Cat olica de Chile, Dermatology Service, Las Condes Clinic, Santiago, Chile, Department of Medicine and Medical Divisions, University of Alcal a, Madrid, Spain, Memorial Sloan Kettering Cancer Center, New York, USA, and Department of Pathology, Faculty of Medicine, Pontificia Universidad Cat olica de Chile, Santiago, Chile

Concomitant poroma and porocarcinoma

Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level clinical suspicion together with surgical excision and histopathology for prompt diagnosis confirmation.

Nasal Tumoral Lesion: Answer

CLINICAL COURSE AND MICROSCOPIC FINDINGS The immunohistochemical study of the nasal tumoral lesion, using an automated Envison Flex technique with monoclonal antibodies, showed a positive reaction for CD10 and renal cell carcinoma antigen (RCC) (Fig. 3) and a negative reaction for CD31, CD34, and thyroid transcription factor-1 (TTF-1). These findings were consistent with an ulcerated clear cell carcinoma of renal origin. The computed tomography disclosed metastatic foci at cerebral, pulmonary, hepatic, peritoneal, mediastinal, hiliar, and retroperitoneal levels and a left subphrenic mass, with infiltration of the ipsilateral adrenal gland, consistent with local recurrence of the renal carcinoma diagnosed 6 years ago. It was decided to initiate treatment with pazopanib (Votrient). Nevertheless, the patient died 4 months after the diagnosis of cutaneous metastatic disease.