Aly Ghoneim
Montreal Heart Institute
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Publication
Featured researches published by Aly Ghoneim.
The Journal of Thoracic and Cardiovascular Surgery | 2016
Ismail Bouhout; A. Mazine; Aly Ghoneim; Xavi Millàn; Ismail El-Hamamsy; Michel Pellerin; Raymond Cartier; Phillipe Demers; Yoan Lamarche; Denis Bouchard
OBJECTIVES The aim of this study was to determine immediate results and long-term outcomes after surgical management of paravalvular leak (PVL). METHODS Between 1995 and 2012, a total of 190 patients underwent primary surgical repair (n = 142) or valve replacement (n = 48) for a PVL at our institution. The PVL was mild in 6 (3%) patients, moderate in 85 (45%), moderate to severe in 84 (44%), and severe in 15 (8%). Among these, 120 (63%) had PVL in the mitral position, 63 (33%) had PVL in the aortic position, and 7 (4%) had PVL in both valves. Mean follow-up was 5.3 ± 4.6 years. RESULTS Mean age at surgery was 63 ± 12 years (64% men). Operative mortality occurred in 13 (7%) patients (10 [8%] in mitral; 2 [3%] in aortic; and 1 [14%] in double valve procedures). Survival at 1, 5, and 10 years was 85% ± 3%, 73% ± 4%, and 56% ± 5%, respectively. The cumulative incidence of PVL recurrence was 3% ± 1%, 14% ± 3%, and 32% ± 6%, at 1, 5, and 10 years, respectively. The number of previous surgeries was a predictor of survival and PVL recurrence. Freedom from New York Heart Association class ≥III was 96% ± 2%, 82% ± 4%, and 58% ± 6%, at 1, 5, and 10 years, respectively. The freedom from rehospitalization for heart failure was 92% ± 2%, 83% ± 4%, and 67% ± 6%, at 1, 5, and 10 years. CONCLUSIONS Surgical treatment of PVL resulted in acceptable outcomes. Nevertheless, the continued risk of PVL recurrence is higher in patients who have had multiple previous surgeries. More studies are needed to compare these results with the transcatheter PVL reduction technique.
Interactive Cardiovascular and Thoracic Surgery | 2017
Ismail Bouhout; Pierre-Emmanuel Noly; Aly Ghoneim; Louis-Mathieu Stevens; Raymond Cartier; Nancy Poirier; Denis Bouchard; Philippe Demers; Ismail El-Hamamsy
OBJECTIVES The aim of this study was to compare perioperative outcomes in young adults following isolated Ross procedure versus mechanical aortic valve replacement (AVR) in a high-volume centre. METHODS From 2007 to 2015, 337 elective isolated mechanical AVRs and 137 Ross procedures were performed in young adults (<65 years) at our centre. Using a 1:1 propensity score match analysis, 140 patients were included in the study (n = 70 in each group). Perioperative outcomes were defined using STS guidelines. The primary outcome was operative mortality. RESULTS Median age was 52 [14] years and EuroSCORE II was 1.0 [0.4]%. There were no mortalities in the two groups. There were no differences in the incidence of myocardial injury (0% overall) and neurological complications (0.7% overall). Three (4%) reinterventions for bleeding were required in the Ross cohort versus six (9%) in the mechanical AVR cohort (P = 0.49). A significant increase in serum creatinine (>2-fold increase) was more commonly observed after the Ross procedure (11 vs 1%; P = 0.03), but there was no significant difference in the rate of temporary dialysis. Twenty-seven patients (39%) required ≥1 blood product transfusion in the Ross group, whereas 21 patients (31%) did so in the mechanical AVR group (P = 0.47). Median hospital length of stay was similar in both the groups (6 days). CONCLUSIONS There are no differences in mortality or major perioperative outcomes in adults undergoing an isolated Ross procedure or mechanical AVR.
The Journal of Thoracic and Cardiovascular Surgery | 2016
Aly Ghoneim; Ismail Bouhout; Philippe Demers; A. Mazine; Mary Francispillai; Ismail El-Hamamsy; Michel Carrier; Yoan Lamarche; Denis Bouchard
The Annals of Thoracic Surgery | 2017
Ismail Bouhout; A. Mazine; Lena Rivard; Aly Ghoneim; Ismail El-Hamamsy; Yoan Lamarche; Michel Carrier; Philippe Demers; Denis Bouchard
Canadian Journal of Cardiology | 2017
Ismail Bouhout; Aly Ghoneim; Nancy Poirier; Raymond Cartier; Philippe Demers; Louis P. Perrault; Ismail El-Hamamsy
Canadian Journal of Cardiology | 2014
A. Mazine; Aly Ghoneim; Ismail Bouhout; William Fortin; Ilyes Berania; Philippe L. L'Allier; Patrick Garceau; Denis Bouchard
The Journal of Thoracic and Cardiovascular Surgery | 2017
Gilles Amr; Aly Ghoneim; Genevieve Giraldeau; Philippe Demers
The Annals of Thoracic Surgery | 2017
Aly Ghoneim; Ismail Bouhout; Louis P. Perrault; Denis Bouchard; Michel Pellerin; Yoan Lamarche; Philippe Demers; Michel Carrier; Raymond Cartier; Ismail El-Hamamsy
The Annals of Thoracic Surgery | 2018
Amine Mazine; Aly Ghoneim; Ismail El-Hamamsy
Current Opinion in Cardiology | 2018
Aly Ghoneim; Ismail Bouhout; Fahd Makhdom; Michael W.A. Chu