Alyssa W. Goldman

Bioregulatory systems medicine: an innovative approach to integrating the science of molecular networks, inflammation, and systems biology with the patient's autoregulatory capacity?

Bioregulatory systems medicine (BrSM) is a paradigm that aims to advance current medical practices. The basic scientific and clinical tenets of this approach embrace an interconnected picture of human health, supported largely by recent advances in systems biology and genomics, and focus on the implications of multi-scale interconnectivity for improving therapeutic approaches to disease. This article introduces the formal incorporation of these scientific and clinical elements into a cohesive theoretical model of the BrSM approach. The authors review this integrated body of knowledge and discuss how the emergent conceptual model offers the medical field a new avenue for extending the armamentarium of current treatment and healthcare, with the ultimate goal of improving population health.

Parental Incarceration and Child Health in the United States

Mass incarceration has profoundly restructured the life courses of not only marginalized adult men for whom this event is now so prevalent but also their families. We examined research published from 2000 to 2017 on the consequences of parental incarceration for child health in the United States. In addition to focusing on specific health outcomes, we also considered broader indicators of child well-being because there has been little research on the association between parental incarceration and objectively measured child health outcomes. Our findings support 4 conclusions. First, paternal incarceration is negatively associated-possibly causally so-with a range of child health and well-being indicators. Second, although some research has suggested a negative association between maternal incarceration and child health, the evidence on this front is mixed. Third, although the evidence for average effects of paternal incarceration on child health and well-being is strong, research has also suggested that some key factors moderate the association between paternal incarceration and child health and well-being. Finally, because of the unequal concentration of parental incarceration and the negative consequences this event has for children, mass incarceration has increased both intracountry inequality in child health in the United States and intercountry inequality in child health between the United States and other developed democracies. In light of these important findings, investment in data infrastructure-with emphasis on data sets that include reliable measures of parental incarceration and child health and data sets that facilitate causal inferences-is needed to understand the child health effects of parental incarceration.

Settling In: The Role of Individual and Departmental Tactics in the Development of New Faculty Networks.

Abstract:Network formation is a key element of newcomer socialization; however, little is understood about how newcomer networks are formed in higher education. Drawing on a series of interviews with 34 new pre-tenure faculty members, we propose that just as individual and organizational socialization tactics interactively influence newcomer adjustment (Gruman, Saks, & Zweig, 2006), so too will they affect new faculty experiences with network formation. Our findings support this proposal; that is, individual employee characteristics, the practices of specific departments within the larger university, and the interaction between the two, create different degrees of network integration for faculty. Further, we find that in the context of university departments, organizational tactics may have a more significant effect on network development (and potentially other socialization outcomes) than those that stem from the individual. Building upon these findings, we also identify factors that facilitate new faculty network development and use these factors to suggest practical guidance for universities striving to enhance new faculty integration.

How much would eliminating drug crimes decrease racial/ethnic gaps in criminal conviction?

Since the 1970s, criminal justice contact has become an increasingly common event in early adulthood, and disproportionately so for African American men. Policymakers often argue that reducing drug-related conviction rates is among the easiest ways to reduce racial/ethnic disparities in incarceration. These arguments are often backed by statistics that convey the number of drug offenders in contact with the criminal justice system at a given point in time. Unfortunately, we know little about the extent to which over-time conviction risk and associated racial/ethnic disparities may be affected by drug-related policy changes. Using a novel application of the single decrement life table to analyze data from the National Longitudinal Survey of Youth 1997 (NLSY97), I present a quantitative thought experiment to consider the extent to which the elimination of drug-related offenses would affect racial/ethnic disparities in mens cumulative probability of conviction by age 30. Consistent with prior research, results indicate that black men are at disproportionately higher risk of ever experiencing a drug-related conviction, and of experiencing a drug-related conviction at each conviction instance. More surprising, however, is the finding that while the removal of drug sentencing may significantly impact racial/ethnic disparities associated with conviction, only a relatively small proportion of those ever convicted would avoid conviction altogether in the absence of drug-related sentencing.