Amar P Patel

Ocriplasmin for foveal schisis in X-linked retinoschisis.

PURPOSE To report a case of foveal schisis in X-linked retinoschisis treated with ocriplasmin. METHODS Case report. RESULTS A 27-year-old man with X-linked retinoschisis was treated with a single intravitreal injection of ocriplasmin. After injection, a posterior vitreous detachment was induced and the macular schisis cavity resolved at 1 week. Central macular thickness on optical coherence tomography decreased from 731 μm to 185 μm, visual acuity remained unchanged, and there were no adverse events. However, the macular schisis cavity recurred at 1 month. CONCLUSION This is the first reported case of using ocriplasmin to treat foveal schisis in X-linked retinoschisis. Although vitreomacular traction was relieved, the schisis cavity recurred shortly after initial closure.