Amin Rostami

Copper-Catalyzed Thioetherification Reactions of Alkyl Halides, Triphenyltin Chloride, and Arylboronic Acids with Nitroarenes in the Presence of Sulfur Sources

In this article, we report three odorless methods for the thioarylation and thioalkylation of different nitroarenes using alkyl halides (Br, Cl), triphenyltin chloride, and arylboronic acids as the coupling partners. Triphenyltin chloride is capable of delivering all of its phenyl groups to the product. Depending on the reaction, sodium thiosulfate pentahydrate (Na2S2O3·5H2O), S8/KF, and S8/NaOH systems are found to be effective sources of sulfur in the presence of copper salts. The use of green solvents, inexpensive catalysts, and user-friendly starting materials has made these methods interesting from a green chemistry standpoint.

Magnetic nanoparticle-supported guanidine as a highly recyclable and efficient nanocatalyst for the cyanosilylation of carbonyl compounds

Guanidine supported onto magnetic Fe3O4 nanoparticles was prepared and evaluated as a recoverable interphase nanocatalyst for the cyanosilylation of carbonyl compounds in good to high yields using trimethylsilylcyanide (TMSCN) in CH2Cl2 at room temperature. This simple experimental and product isolation procedure combined with easy recovery and high reusability (up to 20) of the catalyst are expected to contribute to the development of clean strategy for the preparation of silylated cyanohydrins.

Layer by layer assembly of catalase and amine-terminated ionic liquid onto titanium nitride nanoparticles modified glassy carbon electrode: Study of direct voltammetry and bioelectrocatalytic activity

A novel, simple and facile layer by layer (LBL) approach is used for modification of glassy carbon (GC) electrode with multilayer of catalase and nanocomposite containing 1-(3-Aminopropyl)-3-methylimidazolium bromide (amine terminated ionic liquid (NH(2)-IL)) and titanium nitride nanoparticles (TiNnp). First a thin layer of NH(2)-IL is covalently attached to GC/TiNnp electrode using electro-oxidation method. Then, with alternative self assemble positively charged NH(2)-IL and negatively charged catalase a sensitive H(2)O(2) biosensor is constructed, whose response is directly correlated to the number of bilayers. The surface coverage of active catalase per bilayer, heterogeneous electron transfer rate constant (k(s)) and Michaelis-Menten constant (K(M)) of immobilized catalase were 3.32×10(-12) mol cm(-2), 5.28s(-1) and 1.1 mM, respectively. The biosensor shows good stability, high reproducibility, long life-time, and fast amperometric response with the high sensitivity of 380 μA mM(-1)cm(-2) and low detection limit of 100 nM at concentration range up to 2.1 mM.

N-Bromophthalimide [NBPI] as a powerful oxidizing agent for the facile and chemoselective oxidation of thiols to symmetrical disulfides

A new application of N-bromophthalimide for the facile oxidation of thiols to their corresponding symmetrical disulfides is described. A wide variety of thiols (aromatic, aliphatic and heterocyclic) were selectively oxidised to their corresponding disulfides with [NBPI] in a mixture of acetone and water under microwave irradiation in a microwave oven at a power output of 650W.

Green and Efficient Procedure for the Trimethylsilylation of Hydroxy Groups and Their Regeneration Using Sulfamic Acid as Recyclable Catalyst

Structurally diverse alcohols and phenols were efficiently transformed into their corresponding trimethylsilyl ethers with hexamethyldisilazane (HMDS) in the presence of catalytic amounts of sulfamic acid (SA) at room temperature under both acetonitrile and solvent-free conditions. Deprotection of these trimethylsilyl ethers to their parent alcohols and phenols was also achieved using this catalyst in water at room temperature.

Ligand-free Cu-catalyzed odorless synthesis of unsymmetrical sulfides through cross-coupling reaction of aryl/benzyl/alkyl halides with an aryl boronic acid/S8 system as a thiolating agent in PEG

In this article, we have presented a novel, efficient and environmentally benign method for one-pot, one-step and odorless synthesis of a wide range of unsymmetrical sulfides from the reaction of aryl/benzyl/alkyl halides with aryl boronic acids in the presence of S8, NaOH and a catalytic amount of CuI in PEG200 as green solvent at 40–60 °C. The products were obtained in moderate to excellent yields. More importantly, this reaction is applicable for the gram-scale preparation of the desired sulfides.

N,N-dichloro-4-methylbenzenesulphonimide as a novel and efficient catalyst for acetylation of alcohols under mild conditions

Structurally diverse alcohols were acetylated in a clean and efficient reaction with acetic anhydride based on the use of a catalytic amount of N,N-dichloro-4-methylbenzenesulphonimide in dichloromethane. All reactions were performed at room temperature in good to excellent yields.

Magnetic nanoparticles Fe3O4-supported guanidine as an efficient nanocatalyst for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones under solvent-free conditions

Here, the application of guanidine supported on magnetic nanoparticles Fe3O4 (MNPs-guanidine) as a novel magnetically separable base nanocatalyst is described. We have investigated the application of this new catalyst for the synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives from the three-component, one-pot condensation reaction of phthalhydrazide, cyclic 1,3-dicarbonyl, and aromatic aldehydes under solvent-free conditions. The products were obtained in short reaction times with good to high yields. The supported catalyst could be simply separated and recovered from the reaction mixture with the assistance of an external magnet and reused 18 times with little loss of activity.

Selective Oxidation of Sulfides to Sulfoxides using H2O2 Catalyzed by p-Toluenesulfonic Acid (p-TsOH) Under Solvent-Free Conditions

Abstract An efficient, chemoselective, and environmental friendly procedure for the oxidation of sulfides to sulfoxides is described. Various types of aromatic and aliphatic sulfides are selectively oxidized to sulfoxides in good to excellent yields using 30% H2O2 in the presence of catalytic amounts of a p-TsOH under solvent-free conditions at room temperature. GRAPHICAL ABSTRACT

A mild and selective method for the conversion of oximes into ketones and aldehydes by the use of N-bromophthalimide

N-Bromophthalimide has been found to be an efficient and selective reagent for the mild oxidative cleavage of oximes to yield their corresponding carbonyl compounds in good to excellent yields.