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Featured researches published by Amol Karmarkar.


JAMA | 2014

Thirty-Day Hospital Readmission Following Discharge From Postacute Rehabilitation in Fee-for-Service Medicare Patients

Kenneth J. Ottenbacher; Amol Karmarkar; James E. Graham; Yong Fang Kuo; Anne Deutsch; Timothy A. Reistetter; Soham Al Snih; Carl V. Granger

IMPORTANCE The Centers for Medicare & Medicaid Services recently identified 30-day readmission after discharge from inpatient rehabilitation facilities as a national quality indicator. Research is needed to determine the rates and factors related to readmission in this patient population. OBJECTIVE To determine 30-day readmission rates and factors related to readmission for patients receiving postacute inpatient rehabilitation. DESIGN, SETTING, AND PATIENTS Retrospective cohort study of records for 736,536 Medicare fee-for-service beneficiaries (mean age, 78.0 [SD, 7.3] years) discharged from 1365 inpatient rehabilitation facilities to the community in 2006 through 2011. Sixty-three percent of patients were women, and 85.1% were non-Hispanic white. MAIN OUTCOMES AND MEASURES Thirty-day readmission rates for the 6 largest diagnostic impairment categories receiving inpatient rehabilitation. These included stroke, lower extremity fracture, lower extremity joint replacement, debility, neurologic disorders, and brain dysfunction. RESULTS Mean rehabilitation length of stay was 12.4 (SD, 5.3) days. The overall 30-day readmission rate was 11.8% (95% CI, 11.7%-11.8%). Rates ranged from 5.8% (95% CI, 5.8%-5.9%) for patients with lower extremity joint replacement to 18.8% (95% CI, 18.8%-18.9%). for patients with debility. Rates were highest in men (13.0% [ 95% CI, 12.8%-13.1%], vs 11.0% [95% CI, 11.0%-11.1%] in women), non-Hispanic blacks (13.8% [95% CI, 13.5%-14.1%], vs 11.5% [95% CI, 11.5%-11.6%] in whites, 12.5% [95% CI, 12.1%-12.8%] in Hispanics, and 11.9% [95% CI, 11.4%-12.4%] in other races/ethnicities), beneficiaries with dual eligibility (15.1% [95% CI, 14.9%-15.4%], vs 11.1% [95% CI, 11.0%-11.2%] for no dual eligibility), and in patients with tier 1 comorbidities (25.6% [95% CI, 24.9%-26.3%], vs 18.9% [95% CI, 18.5%-19.3%] for tier 2, 15.1% [95% CI, 14.9%-15.3%] for tier 3, and 9.9% [95% CI, 9.9%-10.0%] for no tier comorbidities). Higher motor and cognitive functional status were associated with lower hospital readmission rates across the 6 impairment categories. Adjusted readmission rates by state ranged from 9.2% to 13.6%. Approximately 50% of patients rehospitalized within the 30-day period were readmitted within 11 days of discharge. Medicare Severity Diagnosis-Related Group codes for heart failure, urinary tract infection, pneumonia, septicemia, nutritional and metabolic disorders, esophagitis, gastroenteritis, and digestive disorders were common reasons for readmission. CONCLUSIONS AND RELEVANCE Among postacute rehabilitation facilities providing services to Medicare fee-for-service beneficiaries, 30-day readmission rates ranged from 5.8% to 18.8% for selected impairment groups. Further research is needed to understand the causes of readmission.


Archives of Physical Medicine and Rehabilitation | 2012

Small Sample Research Designs for Evidence-based Rehabilitation: Issues and Methods

James E. Graham; Amol Karmarkar; Kenneth J. Ottenbacher

Conventional research methods, including randomized controlled trials, are powerful techniques for determining the efficacy of interventions. These designs, however, have practical limitations when applied to many rehabilitation settings and research questions. Alternative methods are available that can supplement findings from traditional research designs and improve our ability to evaluate the effectiveness of treatments for individual patients. The focus on individual patients is an important element of evidenced-based rehabilitation. This article examines one such alternate approach: small-N research designs. Small-N designs usually focus on 10 or fewer participants whose behavior (outcomes) are measured repeatedly and compared over time. The advantages and limitations of various small-N designs are described and illustrated using 3 examples from the rehabilitation literature. The challenges and opportunities of applying small-N designs to enhance evidence-based rehabilitation are discussed.


Journals of Gerontology Series A-biological Sciences and Medical Sciences | 2012

Hospital Readmission in Persons With Stroke Following Postacute Inpatient Rehabilitation

Kenneth J. Ottenbacher; James E. Graham; Allison J. Ottenbacher; Jinhyung Lee; S. Al Snih; Amol Karmarkar; Timothy A. Reistetter; Glenn V. Ostir

BACKGROUND Readmission is an important quality indicator following acute care hospitalization. We examined factors associated with hospital readmission in persons with stroke following postacute inpatient rehabilitation. METHODS Prospective cohort study including 674 persons with stroke who received rehabilitation at 11 facilities located in eight states and the District of Columbia. Measures included hospital readmission within 3 months of discharge, sociodemographic characteristics, length of stay, primary payment source, comorbidities, stroke type, standardized assessments of motor and cognitive function, depressive symptoms, and social support. RESULTS Mean age was 71.5 years (SD = 10.5). Twenty-five percent of patients reported high depressive symptoms. Overall, 18% (n = 122) of the sample was rehospitalized. Univariate analyses showed that people who were rehospitalized were more likely (p < .05) to be non-Hispanic white, married, demonstrate less functional independence at discharge, experience longer lengths of stay in rehabilitation, and report more depressive symptoms and lower social support. In the fully adjusted multivariable hierarchical generalized linear model, motor functional status (OR = 0.98, 95% CI 0.96-0.99), depressive symptoms (OR = 1.80, 95% CI 1.06-3.05), and social support (OR = 2.28, 95% CI 1.29-4.03) remained statistically significant. In addition, a minority-by-depressive symptoms interaction term also reached statistical significance. CONCLUSION Functional status, depressive symptoms, and social support were important predictors of hospital readmission. These variables are not included in most administrative data sets. Future research to develop useful risk-adjustment models for rehospitalization following postacute inpatient rehabilitation services should include large diverse samples and explore practical sources for additional meaningful information.


Journal of Aging and Health | 2012

Frailty as a predictor of falls in older Mexican Americans

Rafael Samper-Ternent; Amol Karmarkar; James E. Graham; Timothy A. Reistetter; Kenneth J. Ottenbacher

Objective: Examine the relationship between frailty and falls. Method: A total of 847 Mexican Americans from the Hispanic Established Population for the Epidemiological Study of the Elderly were evaluated. The outcome variable was fall occurrence. Some predictor variables included were frailty, sociodemographic variables, functional and health status, and prior falls. Results: Those who fell were more likely to be women, not married, had prior falls, more functional problems and poorer health. The incidence rate ratio (IRR) for falls was 1.9 for nonfrail individuals and 3.2 for frail individuals. Prefrail individuals had 1.36 higher odds of falls (95% CI [1.11, 1.67]), individuals with prior falls had 1.26 higher odds of falls (95% CI [1.15, 1.37]), and those with poor balance had 1.49 higher odds of falls (95% CI [1.15, 1.95]) over the 2 years (p < .01). Discussion: Frailty increases the odds of falls in older Mexican Americans. Interventions tailored to reduce fall incidence and improve health care quality for older Mexican Americans are needed.


Journal of the American Geriatrics Society | 2012

Routine physical activity and mortality in Mexican Americans aged 75 and older.

Allison J. Ottenbacher; Soham Al Snih; Amol Karmarkar; Jinhyung Lee; Rafael Samper-Ternent; Amit Kumar; Saad M. Bindawas; Kyriakos S. Markides; Kenneth J. Ottenbacher

To examine the association between routine physical activity and risk of 3‐year mortality in Mexican Americans aged 75 and older.


Journal of Rehabilitation Research and Development | 2008

Quality of medical care provided to service members with combat- related limb amputations: Report of patient satisfaction

Paul F. Pasquina; Jack W. Tsao; Diane M. Collins; Brenda L. Chan; Alexandra Charrow; Amol Karmarkar; Rory A. Cooper

A group of 158 service members who sustained major limb amputations during the global war on terrorism were surveyed on their satisfaction with the quality of care received from the Walter Reed Army Medical Center (WRAMC) Amputee Clinic from the time of their injury to their inpatient discharge. Of these participants, 96% were male, 77% were Caucasian, 89% were enlisted personnel, and 68% had sustained lower-limb amputations. WRAMC inpatient therapy, peer visitors, overall medical care, and pain management received particularly high satisfaction ratings. Age, race, rank, and level and side of amputation had little effect on overall satisfaction ratings. Significant differences, however, were found by location of injury (Iraq vs Afghanistan, Cuba, and Africa) regarding satisfaction with care received while in Europe and with the education process at WRAMC. Study findings strongly support the rehabilitation-based, integrative care approach designed by the U.S. military to care for service members with amputations.


Archives of Physical Medicine and Rehabilitation | 2011

Investigation of Factors Associated With Manual Wheelchair Mobility in Persons With Spinal Cord Injury

Michelle L. Oyster; Amol Karmarkar; Mary Patrick; Mary Schmidt Read; Lori Nicolini; Michael L. Boninger

OBJECTIVE To quantify wheelchair mobility of persons with a spinal cord injury (SCI), and to assess the relationship between wheelchair mobility and demographics, type of manual wheelchair, and participation. DESIGN Cross-sectional study. SETTING Six Model Spinal Cord Injury Systems. PARTICIPANTS People (N=132) with SCI who use a manual wheelchair as their primary means of mobility. INTERVENTIONS Not applicable. MAIN OUTCOME MEASURES Wheelchair-related mobility characteristics measured by a data-logging device, and community participation measured by the short form of the Craig Handicap Assessment Recording Technique (CHART). RESULTS Age was found to be significantly (r=-.225, P<.01) related to average speed traveled per day. Whites were found to travel significantly further (P<.01) and accumulate more minutes per day (P<.01) compared with minorities. Participants who were employed traveled significantly further (P<.01), faster (P<.01), and for more minutes per day (P<.01) compared with those who were not employed. A moderate relationship (r=.245-.390) was found between wheelchair mobility data and CHART total score. CONCLUSIONS Results suggest a need for future investigation of the factors that influence wheelchair mobility and community participation of persons with SCI. Findings indicate the efficacy of a quantitative method to track wheelchair mobility in community settings, which could serve as a way of identifying community participation for persons with SCI and possibly uncovering additional aspects of participation.


Assistive Technology | 2007

Review of the use of physical restraints and lap belts with wheelchair users

Eliana S. Chaves; Rory A. Cooper; Diane M. Collins; Amol Karmarkar; Rosemarie Cooper

Wheelchair-related physical restraints, lap belts, and other alternatives are intended to provide safe and adequate seating and mobility for individuals using wheelchairs. Physical restraints and lap belts are also helpful for positioning people in their wheelchairs to reduce the risk of injury during wheelchair tips and falls. However, when used improperly or in ways other than intended, injury or even death can result. Although widely prescribed, little evidence is available to direct professionals on the appropriate use of these restraints and lap belts and for whom these restraints are indicated. The purpose of this study was to conduct a review of available literature from 1966–2006 to identify the risks and benefits associated with lap belts while seated in wheelchairs. Twenty-five studies that met the inclusion criteria were reviewed. Nine studies reported the frequency of asphyxial deaths caused by physical restraints, nine studies reported the long-term complication and indirect adverse effects of physical restraints and lap-belt use, and seven studies reported the benefits of physical restraints and lap belts with individuals using wheelchairs. Despite the weak evidence, the results suggest a considerable number of deaths from asphyxia caused by the use of physical restraints occurred each year in the U.S. The majority of the deaths occurred in nursing homes, followed by hospitals, and then the home of the person. Most deaths occurred while persons were restrained in wheelchairs or beds. Based on that, caution needs to be exercised when using restraints or positioning belts. In addition, other seating and environment alternatives should be explored prior to using restraints or positioning belts, such as power wheelchair seating options. Positioning belts may reduce risk of falls from wheelchairs and should be given careful consideration, but caution should be exercised if the individual cannot open the latch independently. Also, the duration of use of the physical restraint should be limited. Therefore, several factors should be considered when devising a better quality of physical-restraint services provided by health care professionals. These efforts can lead to improved safety and quality of life for individuals who use wheelchairs.


Archives of Physical Medicine and Rehabilitation | 2008

Development of a Wheelchair Virtual Driving Environment: Trials With Subjects With Traumatic Brain Injury

Donald M. Spaeth; Harshal P. Mahajan; Amol Karmarkar; Diane M. Collins; Rory A. Cooper; Michael L. Boninger

OBJECTIVE To develop and test a wheelchair virtual driving environment that can provide quantifiable measures of driving ability, offer driver training, and measure the performance of alternative controls. DESIGN A virtual driving environment was developed. The wheelchair icon is displayed in a 2-dimensional, birds eye view and has realistic steering and inertial properties. Eight subjects were recruited to test the virtual driving environment. They were clinically evaluated for range of motion, muscle strength, and visual field function. Driving capacity was assessed by a brief trial with an actual wheelchair. During virtual trials, subjects were seated in a stationary wheelchair; a standard motion sensing joystick (MSJ) was compared with an experimental isometric joystick by using a repeated-measures design. SETTING Subjects made 2 laboratory visits. The first visit included clinical evaluation, tuning the isometric joystick, familiarization with virtual driving environment, and 4 driving tasks. The second visit included 40 trials with each joystick. PARTICIPANTS Subjects (n=8; 7 men, 1 woman) with a mean age of 22.65+/-2y and traumatic brain injury, both ambulatory and nonambulatory, were recruited. INTERVENTIONS The MSJ used factory settings. A tuning program customized the isometric joystick transfer functions during visit 1. During the second visit, subjects performed 40 trials with each joystick. MAIN OUTCOME MEASURE The root mean square error (RMSE) was defined as the average deviation from track centerline (in meters) and speed (in m/s). RESULTS Data analysis from the first 8 subjects showed no statistically significant differences between joysticks. RMSE averaged .12 to .21m; speed averaged .75m/s. For all tasks and joysticks, driving in reverse resulted in a higher RMSE and more virtual collisions than forward driving. RMSE rates were greater in left and right turns than straight and docking tasks. CONCLUSIONS Testing with instrumented real wheelchairs can validate the virtual driving environment and assess whether virtual driving skills transfer to actual driving.


American Journal of Physical Medicine & Rehabilitation | 2012

The uniform data system for medical rehabilitation: Report of patients with traumatic spinal cord injury discharged from rehabilitation programs in 2002-2010

Carl V. Granger; Amol Karmarkar; James E. Graham; Anne Deutsch; Paulette Niewczyk; Margaret A. DiVita; Kenneth J. Ottenbacher

Objective This study aimed to provide benchmarking information from a large national sample of patients receiving inpatient rehabilitation after a traumatic spinal cord injury. Design This was an analysis of secondary data from 891 inpatient medical rehabilitation facilities in the United States that contributed traumatic spinal cord injury data to the Uniform Data System for Medical Rehabilitation from January 2002 to December 2010. Variables analyzed included demographic information (age, sex, marital status, race/ethnicity, prehospital living setting, discharge setting), hospitalization information (length of stay, program interruptions, payer, onset date, rehabilitation impairment group, International Classification of Diseases 9 codes for admitting diagnosis, co-morbidities), and functional status (Functional Independence Measure [FIM] instrument ratings at admission and discharge, FIM efficiency, FIM gain). Results The final sample included 47,153 patients with traumatic spinal cord injury. Overall, the mean length of stay was 26.2 ± 23.2 days: yearly means ranged from 29.7 ± 25.4 in 2002 to 22.9 ± 18.9 in 2009. FIM total admission and discharge ratings also declined during the 8-yr study period; admission decreased from 60.5 ± 17.4 to 55.9 ± 16.3; discharge decreased from 86.1 ± 23.8 to 82.4 ± 23.4. Rehabilitation efficiency (FIM gain per day) remained relatively stable over time (1.6 ± 1.7 points per day). The percentage of all patients discharged to the community ranged from 75.8% to 71.5% per year. Wheelchair users stayed in rehabilitation longer than did persons who could walk (34.6 ± 217.4 vs. 17.4 ± 14.1 days) and also experienced less functional improvement (21.6 ± 15.8 vs. 29.6 ± 16.3 FIM points). Conclusions National data from persons with traumatic spinal cord injury in 2002–2010 indicate that lengths of stay declined, but efficiency in functional independence was stable to slightly increased. More than 70% of patients were consistently discharged to community settings after inpatient rehabilitation.

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Kenneth J. Ottenbacher

University of Texas Medical Branch

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James E. Graham

University of Texas Medical Branch

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Amit Kumar

University of Texas Medical Branch

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Rory A. Cooper

University of Pittsburgh

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Timothy A. Reistetter

University of Texas Medical Branch

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Yong Fang Kuo

University of Texas Medical Branch

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