Ana Paula Dornelles da Silva Manzoni

Acute hemorrhagic edema of infancy: a case report

Background  Acute hemorrhagic edema of infancy (AHEI), or Seidlmayers disease, is a type of leukocytoclastic vasculitis proper of infants and children. It is characterized by a local increase in temperature, erythematous edema and purpuric lesions involving mainly the face and extremities. There usually is no visceral involvement. The disease is self‐limited, bearing a benign clinical course. Infection, drugs and immunization have been considered as precipitating factors. The main differential diagnosis is Henoch‐Schönlein purpura (HSP).

Assessment of the quality of life of pediatric patients with the major chronic childhood skin diseases

BACKGROUND The skin is the primary interface of the human being with the external environment and the presence of skin diseases can have substantial effects on the quality of life. OBJECTIVE This study aims to make a comparative evaluation of the quality of life of pediatric patients with atopic dermatitis, psoriasis and vitiligo and correlate the findings with the total body surface and the areas with the disease exposed to view. METHODS The sample consisted of 118 patients with atopic dermatitis, vitiligo and psoriasis, aged between 5 and 16 years, who were asked to answer the Childrens Dermatology Life Quality Index (CDLQI) questionnaire. A dermatological examination for the measurement of total body surface affected by the disease was performed. RESULTS The three groups showed an impaired quality of life. Patients with atopic dermatitis and psoriasis showed a significantly greater impact on the QoL than the group with vitiligo. There is a trend towards impaired quality of life in patients from the three groups of dermatoses, which is related to increments in both the total affected area and affected area exposed to view (r = 0.428 and p <0.001, r = 0.381 and p <0.001, respectively). CONCLUSION The assessed children had impaired quality of life. However, there is a significantly greater impact in the groups with atopic dermatitis and psoriasis than in the group with vitiligo. This may be due to lack of symptoms in vitiligo and the fact this group presented a statistically smaller affected body surface than the other two groups.

Treatment of Granulosis Rubra Nasi with Botulinum Toxin Type A

e report on the case of a 16-year-old boy whopresented with a 12-year history of erythemaand hyperhidrosis of the nose; signs, symptoms, andhistological findings were consistent with granulosisrubra nasi. The treatment of granulosis rubra nasiwith botulinum toxin type A resulted in significantimprovement of clinical symptoms and psychosocialcomplications.

Skin changes after bariatric surgery

Today, obesity is considered an epidemic all over the world and it is recognized as one of the major public health problems. Bariatric surgery is considered an appropriate therapeutic option for obesity with progressively increasing demands. The changes resulting from massive weight loss after bariatric surgery are related to numerous complications. This article will present the dermatological alterations that can be found after bariatric surgery. They will be subdivided into dermatoses that are secondary to metabolic and nutritional disorders, those derived from cutaneous structural modifications after major weight loss and the influence the latter may have in improving of certain dermatoses.

Skin changes in pediatric transplant patients

Abstract:  The advent of organ transplantation identified a new group of diseases. Dermatologists are studying transplant‐associated diseases along with the atypical behavior of already known dermatoses. Pediatric patients have been treated as an extension of adult population, but unique aspects of age required clarification. A prospective cohort was studied including patients from both genders up to 17 yr of age who were recipients of kidney, liver or BMT during 2003 in Porto Alegre, Brazil. Regular skin examinations were performed up to the sixth month after the procedure, and an analysis was determined by ID (i.e. = number of skin changes/number of patients‐month × 100). Thirty‐nine patients were examined: 20 were kidney transplant recipients; 11 were BMT recipients (10 autologous transplants and 1 allogeneic transplant); and 8 were liver transplant recipients. Skin changes result primarily from the use of medication (87.2). Individually, kidney transplant patients presented the highest ID of skin changes because of medications (104.1). BMT recipients presented the highest ID of alterations occurring on skin appendages (85.4) and liver transplant recipients had the highest ID of vascular changes (94.9). In conclusion, this study shows that cutaneous alterations in pediatric transplant recipients present some particularities not described in adult recipients, such as ichthyosiform xerosis in renal recipients and skin scaling with pellagroid appearance in bone marrow recipients. Also, dermatoses secondary to medication use were the main finding in pediatric population.

Dermatosis and Nutritional Disorders

Diet plays an important role in many skin disorders, and dermatologists are frequently faced with the difficulty of separating myth from fact when it comes to dietary advice for their patients. From a practical point of view, the dermatologist will find it useful to keep some dietary information handy in order to deal with the occasional patient who does not seem to respond despite the best scientific and evidence-based therapy. In this chapter we discuss the relationship of nutrition with some dermatoses: acanthosis nigricans, acne, acrodermatitis enteropathica, allergic contact dermatitis, atopic dermatitis, autoimmune cutaneous diseases, bullous diseases, skin manifestations of energy-protein malnutrition, hair disorders, oral mucosa disorders, nail disorders, necrolytic migratory erythema, pellagra, cutaneous signs of peripheral vascular disease, phrynoderma, porphyria, pressure ulcers, psoriasis, rosacea, scurvy, skin cancer, skin infection, urticaria, vitiligo, and skin repercussions of bariatric surgery.