Ana Sofia Santos

Percepção dos treinadores sobre as competências profissionais em função da sua formação e experiência

O objectivo deste estudo consistiu na analise da valorizacao percebida de competencias profissionais em funcao da experiencia profissional e da formacao academica de treinadores. A amostra foi constituida por 343 treinadores portugueses, oriundos de diferentes modalidades. A recolha dos dados foi garantida pela aplicacao de um questionario apos validacao de construcao e de conteudo. Como procedimentos estatisticos, recorreu-se a analise factorial exploratoria e a analise inferencial atraves do teste one-way ANOVA. Da analise das competencias percebidas como importantes, resultaram 5 factores: planeamento; lideranca e formacao de treinadores; planeamento e orientacao das competicoes; aspectos pessoais; e orientacao do treino. Apesar de todas terem sido consideradas, no minimo, com importância razoavel, as relacionadas com o contexto da competicao destacaram-se como as mais valorizadas. A experiencia profissional e a formacao academica apresentaram-se como factores diferenciadores da valorizacao atribuida as competencias. Os treinadores com mais experiencia concederam mais importância as competencias relacionadas com o planeamento, a orientacao do treino, a lideranca e a formacao de treinadores em relacao aos treinadores pouco experientes. Os treinadores com formacao superior valorizaram mais as competencias de planeamento, lideranca e formacao de treinadores, orientacao do treino e competencias pessoais do que os treinadores com o 2o grau completo.

Prevalence of abacavir-associated hypersensitivity syndrome and HLA-B*5701 allele in a Portuguese HIV-positive population

Background: Human Immunodeficiency Virus (HIV)‐positive patients treated with the antiretroviral drug abacavir (ABC) may develop a potentially fatal ABC‐associated hypersensitivity syndrome (ABC‐HS), typically characterized by fever, malaise, rash, vomiting/diarrhoea and/or dyspnoea/cough. ABC‐HS has been strongly associated with HLA‐B*57:01 carriage and screening for this allele is recommended. Objective: To determine the prevalence of HLA‐B*57:01 and to characterize suspected ABC‐HS in the adult HIV population from our hospital during a 7‐year period. Methods: Clinical data on patients under ABC treatment from January 2006 to December 2012 were analyzed to search for symptoms of ABC‐HS. Reactions of suspected ABC‐HS were characterized. HLA‐B*57:01 and patch tests (1% and 10% ABC in petrolatum) with readings at 48 h were performed in those without previous testing. From January 2008 routine HLA‐B*57:01 screening was implemented. Results: From January 2006 to December 2007, 186 patients began treatment with ABC (data from 163 were available): 7 (4%) patients stopped ABC for suspected ABC‐HS (71% males, median age 45 years) and the median time for onset of the reaction after starting ABC was 7 days. Four of the 7 patients had the HLA‐B*57:01 allele and 2 of these 4 had positive patch tests. After HLA‐B*57:01 screening implementation (January 2008), 573 patients were evaluated and 35 (6.1%) were HLA‐B*57:01 positive; no suspected ABC‐HS were observed since then. Conclusion: Four patients with suspected ABC‐HS (of 6 screened) were HLA‐B*57:01 positive. No ABC‐HS occurred since January 2008, after HLA‐B*57:01 screening was implemented.

Primary drug resistance at diagnosis of HIV-1 infection: a Portuguese cohort.

Presence of viral mutations conferring resistance to antiretroviral drugs has potential impact on success of antiretroviral therapy (ART). The aim of this study was to describe the prevalence of resistance‐associated mutations in HIV‐infected patients without prior ART in a Portuguese cohort.

Prevention of mother-to-child transmission: experience of a Portuguese centre.

HIV infection during pregnancy still raises controversial issues. Combined antiretroviral therapy (cART) has been successful in reducing mother‐to‐child transmission (MTCT). Routine screening in pregnancy and in pre‐conception consultation proved to be one of the best methods able to get this treatment on time. We review our experience with pregnant patients with HIV infection.

Factors associated with immune status in the diagnosis of HIV infection

Current guidelines recommend the start of antiretroviral therapy before advanced immunosuppression, which is not always possible. The purpose of this study is to evaluate factors associated with the degree of immunosuppression at the diagnosis of HIV infection.