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Andrea Brüggemann

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Publication

Featured researches published by Andrea Brüggemann.

The EMBO Journal | 1999

Oncogenic potential of EAG K+ channels

Luis A. Pardo; Donato del Camino; Araceli Sánchez; Frauke Alves; Andrea Brüggemann; Synnöve Beckh; Walter Stühmer

We have investigated the possible implication of the cell cycle‐regulated K+ channel ether à go‐go (EAG) in cell proliferation and transformation. We show that transfection of EAG into mammalian cells confers a transformed phenotype. In addition, human EAG mRNA is detected in several somatic cancer cell lines, despite being preferentially expressed in brain among normal tissues. Inhibition of EAG expression in several of these cancer cell lines causes a significant reduction of cell proliferation. Moreover, the expression of EAG favours tumour progression when transfected cells are injected into immune‐depressed mice. These data provide evidence for the oncogenic potential of EAG.

Nature | 1993

Ether-à-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP

Andrea Brüggemann; Luis A. Pardo; Walter Stühmer; Olaf Pongs

Journal of Cell Biology | 1998

Cell Cycle–related Changes in the Conducting Properties of r-eag K+ Channels

Luis A. Pardo; Andrea Brüggemann; Javier Camacho; Walter Stühmer

Proceedings of the National Academy of Sciences of the United States of America | 1997

Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes

Andrea Brüggemann; Walter Stühmer; Luis A. Pardo

Archive | 1999

Human k+ ion channel and therapeutic applications thereof

Synnöve Beckh; Andrea Brüggemann; Camino Fernandez-Miranda Donato Del; Luis Angel Pardo-Fernandez; Perez Araceli Sanchez; Walter Stühmer; Rudiger Weseloh

Archive | 2002

Human K+ channel and prognosing applications thereof

Luis Angel Pardo-Fernandez; Walter Stühmer; Synnöve Beckh; Andrea Brüggemann; Donato Del Camino Fernandez-Miranda; Araceli Sanchez Perez; Rudiger Weseloh

Archive | 2000

Human K+ ion EAG channels

Luis Angel Pardo-Fernandez; Walter Stühmer; Synnöve Beckh; Andrea Brüggemann; Donato Del Camino Fernandez-Miranda; Araceli Sanchez Perez; Rudiger Weseloh

Archive | 2009

METHOD OF DETECTING A CANCER CELL BY ABERRANT EXPRESSION OF A HUMAN K+ ION CHANNEL

Luis Angel Pardo-Fernandez; Walter Stühmer; Synnöve Beckh; Andrea Brüggemann; Donato Del Camino Fernandez-Miranda; Araceli Sanchez Perez; Rudiger Weseloh

Archive | 2006

Antibodies to a human Kchannel and therapeutic applications thereof

Luis Angel Pardo-Fernandez; Walter Stühmer; Synnöve Beckh; Andrea Brüggemann; Donato Del Camino Fernandez-Miranda; Araceli Sanchez Perez; Rudiger Weseloh

Archive | 2003

Human K&plus ion EAG channels

Luis Angel Pardo-Fernandez; Walter Stühmer; Synnöve Beckh; Andrea Brüggemann; Donato Del Camino Fernandez-Miranda; Araceli Sanchez Perez; Rudiger Weseloh

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Collaboration

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Walter Stühmer

Max Planck Society

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Synnöve Beckh

Max Planck Society

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Rudiger Weseloh

Max Planck Society

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Luis A. Pardo

Max Planck Society

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Olaf Pongs

University of Hamburg

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Araceli Sánchez

Max Planck Society

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Frauke Alves

Max Planck Society

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Donato del Camino

Harvard University

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Javier Camacho

CINVESTAV

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