Andrej Kolarovič

Stereoselective sodium borohydride reduction, catalyzed by manganese(II) chloride, of γ-oxo-α-amino acids. A practical approach to syn-γ-hydroxy-α-amino acids

Abstract A highly stereoselective reduction of γ-oxo-α-amino acids by sodium borohydride in the presence of a catalytic amount of manganese(II) chloride gives syn -γ-hydroxy-α-amino acids. Enantiomerically pure syn -(2 S ,4 R ,1′ S )-4-aryl-4-hydroxy-2-(1′-phenylethylamino)butanoic acids form stable gels in methanol.

Crystallization-induced dynamic resolution (CIDR) and its application to the synthesis of unnatural N-substituted amino acids derived from aroylacrylic acids

Abstract A highly stereoselective conjugate addition of chiral amino alcohols affords a simple and inexpensive access to a wide variety of N -functionalized homophenylalanine derivatives. Limitations and conditions for application of CIDR to this system were studied.

Stereoselective dimerization of racemic C3-symmetric Ti(IV) amine triphenolate complexes

A novel, mononuclear Ti(IV) amine triphenolate complex obtained by reaction of Ti(OiPr)(4) with tris(2-hydroxy-3-phenylbenzyl)amine bearing phenyl ortho-substituents affords quantitatively and spontaneously the corresponding heterochiral micro-oxo dinuclear compound whereas an analogous chiral, enantiopure complex maintains its mononuclear structure even in the presence of an excess of water.