Andrew Mitchinson | Researchain

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Featured researches published by Andrew Mitchinson.

Journal of The Chemical Society-perkin Transactions 1 | 1998

Saturated nitrogen heterocycles

Andrew Mitchinson; Alan Nadin

Reviewing the literature published in 1999. Continuing the coverage in J. Chem. Soc., Perkin Trans. 1, 1999, 2553.

Journal of Medicinal Chemistry | 2005

7-(1,1-dimethylethyl)-6-(2-ethyl-2h-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine : A functionally selective γ-aminobutyric AcidA (GABAA) α2/α3-subtype selective agonist that exhibits potent anxiolytic activity but is not sedating in animal models

Robert W. Carling; Andrew Madin; Alec Guiblin; Michael Geoffrey Neil Russell; Kevin William Moore; Andrew Mitchinson; Bindi Sohal; Andrew Pike; Susan M. Cook; Ian Ragan; Ruth M. McKernan; Kathleen Quirk; Pushpinder Ferris; George R. Marshall; Sally Ann Thompson; Keith A. Wafford; Gerard R. Dawson; John R. Atack; José L. Castro; Leslie J. Street

Journal of Medicinal Chemistry | 2005

Discovery of functionally selective 7,8,9,10-tetrahydro-7,10)-ethano-1,2,4-triazolo[3,4-a ]phthalazines as GABAA receptor agonists at the α3 subunit

Michael Geoffrey Neil Russell; Robert W. Carling; John R. Atack; Frances A. Bromidge; Susan M. Cook; Peter Hunt; Catherine Isted; Matt Lucas; Ruth M. McKernan; Andrew Mitchinson; Kevin William Moore; Robert Narquizian; Alison Macaulay; David R. Thomas; Sally-Anne Thompson; Keith A. Wafford; José L. Castro

Archive | 2001

Pyrazolo-triazine derivatives as ligands for gaba receptors

William Robert Carling; Andrew Mitchinson; Michael Geoffrey Neil Russell; Leslie J. Street

Bioorganic & Medicinal Chemistry Letters | 2004

2,5-Dihydropyrazolo[4,3-c]pyridin-3-ones: functionally selective benzodiazepine binding site ligands on the GABAA receptor

Andrew Mitchinson; John R. Atack; Peter Blurton; Robert W. Carling; José L. Castro; Karen S. Curley; Michael Geoffrey Neil Russell; George Marshall; Ruth M. McKernan; Kevin W. Moore; Robert Narquizian; Alison J. Smith; Leslie J. Street; Sally-Anne Thompson; Keith A. Wafford

Bioorganic & Medicinal Chemistry Letters | 2006

A new class of selective, non-basic 5-HT2A receptor antagonists

Tammy Ladduwahetty; Amanda Louise Boase; Andrew Mitchinson; Caroline Quin; Smita Patel; Kerry L. Chapman; Angus Murray Macleod

Archive | 2002

(1, 8) naphthyridines as gaba ligands, their pharmaceutical compositions and uses

William Robert Carling; Andrew Mitchinson; Michael Geoffrey Neil Russell; Leslie J. Street

Archive | 2006

ARYLSULFONYL BENZOFUSED HETEROCYCLES AS 5-HT2A ANTAGONISTS

Neil Roy Curtis; Emanuela Gancia; Tamara Ladduwahetty; Robert James Maxey; Kevin John Merchant; Andrew Mitchinson

Tetrahedron Letters | 2006

Synthesis of pyrido[2,3-d]pyridazines and pyrazino[2,3-d]-pyridazines—novel classes of GABAA receptor benzodiazepine binding site ligands

Andrew Mitchinson; Wesley Peter Blackaby; Sylvie Bourrain; Robert W. Carling; Richard Thomas Lewis

Bioorganic & Medicinal Chemistry Letters | 2006

2,3,7-Trisubstituted pyrazolo[1,5-d][1,2,4]triazines: Functionally selective GABAA α3-subtype agonists

Robert W. Carling; Michael Geoffrey Neil Russell; Kevin W. Moore; Andrew Mitchinson; Alexander Richard Guiblin; Alison J. Smith; Keith A. Wafford; George Marshall; John R. Atack; Leslie J. Street

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