Andrzej Lewandowicz | Researchain

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Featured researches published by Andrzej Lewandowicz.

Journal of Biological Chemistry | 2004

Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION.

Wuxian Shi; Li Min Ting; Gregory A. Kicska; Andrzej Lewandowicz; Peter C. Tyler; Gary B. Evans; Richard H. Furneaux; Kami Kim; Steve C. Almo; Vern L. Schramm

Biochemistry | 2004

Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

Andrzej Lewandowicz; Vern L. Schramm

Journal of Biological Chemistry | 2003

Achieving the Ultimate Physiological Goal in Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase

Andrzej Lewandowicz; Peter C. Tyler; Gary B. Evans; Richard H. Furneaux; Vern L. Schramm

Journal of Biological Chemistry | 2005

Targeting a Novel Plasmodium falciparum Purine Recycling Pathway with Specific Immucillins

Li Min Ting; Wuxian Shi; Andrzej Lewandowicz; Vipender Singh; Agnes Mwakingwe; Matthew R. Birck; Erika A. Taylor Ringia; Graham Bench; Dennis C. Madrid; Peter C. Tyler; Gary B. Evans; Richard H. Furneaux; Vern L. Schramm; Kami Kim

Journal of Medicinal Chemistry | 2003

Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase

Gary B. Evans; Richard H. Furneaux; Andrzej Lewandowicz; Vern L. Schramm; Peter C. Tyler

Journal of Medicinal Chemistry | 2003

Synthesis of Second-Generation Transition State Analogues of Human Purine Nucleoside Phosphorylase

Gary B. Evans; Richard H. Furneaux; Andrzej Lewandowicz; Vern L. Schramm; Peter C. Tyler

Biochemistry | 2003

Over-the-Barrier Transition State Analogues and Crystal Structure with Mycobacterium tuberculosis Purine Nucleoside Phosphorylase†,‡

Andrzej Lewandowicz; Wuxian Shi; Gary B. Evans; Peter C. Tyler; Richard H. Furneaux; Luiz Augusto Basso; Diógenes Santiago Santos; Steven C. Almo; Vern L. Schramm

Biochemistry | 2002

Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase

Greg A. Kicska; Peter C. Tyler; Gary B. Evans; Richard H. Furneaux; Wuxian Shi; Alexander A. Fedorov; Andrzej Lewandowicz; Sean M. Cahill; Steven C. Almo; Vern L. Schramm

Biochemistry | 2003

Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.

Anthony A. Sauve; Sean M. Cahill; Stephan G. Zech; Luiz Augusto Basso; Andrzej Lewandowicz; Diógenes Santiago Santos; Charles Grubmeyer; Gary B. Evans; Richard H. Furneaux; Peter C. Tyler; Ann E. McDermott; Mark E. Girvin; Vern L. Schramm

Journal of the American Chemical Society | 2004