Anil Dhawan
University of Nebraska Medical Center
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Publication
Featured researches published by Anil Dhawan.
Journal of Pediatric Gastroenterology and Nutrition | 1996
Stuart S. Kaufman; Anil Dhawan; Jon A. Vanderhoof; James L. Wisecarver; Stanley J. Radio; Rodney S. Markin; Ira J. Fox; Thomas G. Heffron; Debra Sudan; Todd Pillen; Alan N. Langnas
Following intestinal transplantation, we have found that recovery from severe rejection may be difficult to identify. In this study we sought to ascertain whether concurrent determination of mucosal disaccharidase activities and histologic assessment improves the accuracy of diagnosis of rejection. Histologic changes were graded blindly using a standard set of diagnostic criteria, and these changes were compared over time to maltase, sucrase, lactase, and palatinase activities in four pediatric patients under treatment for severe rejection. The histologic criteria, which included magnitude of enterocyte loss, degree of granulation tissue, severity of villus atrophy, and frequency of apoptosis and cryptitis, were found to correlate with one another over time irrespective of outcome (r = 0.72 to r = 0.85). Enzyme activities were also correlated with each other over time (r = 0.64 to r = 0.80). However, the correlation between histologic diagnosis and enzyme activity was weaker (r = -0.48 to r = -0.57). Furthermore, neither histologic nor enzyme evaluation early in the course of rejection predicted ultimate clinical outcome. The results of this investigation show that determination of mucosal disaccharidase activity provides no additional useful information concerning efficacy of anti-rejection therapy as compared to histologic analysis alone.
Liver Transplantation | 1998
David R. Mack; Anil Dhawan; Stuart S. Kaufman; Alan N. Langnas; Thomas A. Seemayer
Liver Transplantation | 1997
Anil Dhawan; Thomas A. Seemayer; Christina Pinsinski; Thomas G. Gross; Byers W. Shaw; David R. Mack
Pediatric Transplantation | 1998
Thomas M. Attard; Anil Dhawan; Stuart S. Kaufman; Dean S. Collier; Alan N. Langnas
Transplantation proceedings | 1996
Alan N. Langnas; Anil Dhawan; Dean L. Antonson; Stuart S. Kaufman; David R. Mack; Thomas G. Heffron; Ira J. Fox; Shaw Bw; Jon A. Vanderhoof
Pediatric Transplantation | 1998
Stuart S. Kaufman; James L. Wisecarver; Elizabeth Ruby; Ira J. Fox; Debra Sudan; Todd Pillen; Anil Dhawan; Simon Horslen; Jon A. Vanderhoof; Stanley J. Radio; Rodney S. Markin; Alan N. Langnas
Cybercongress : Transplantation in the Next Millennium | 1996
Thomas G. Heffron; Alan N. Langnas; Ira J. Fox; David R. Mack; Anil Dhawan; Stuart S. Kaufman; D. Antonsen; Todd Pillen; Debra Sudan; John T. Jerius; Jon A. Vanderhoof; Jeremiah P. Donovan; Shaw Bw
Cybercongress : Transplantation in the Next Millennium | 1996
Thomas G. Heffron; Alan N. Langnas; Aurelio Matamoros; Joseph C. Anderson; David R. Mack; Timothy M. McCashland; Anil Dhawan; Stuart S. Kaufman; R. K. Zetterman; Todd Pillen; Debra Sudan; John T. Jerius; Jeremiah P. Donovan; Michael F. Sorrell; Jon A. Vanderhoof; B W Jr Shaw
Journal of Pediatric Gastroenterology and Nutrition | 1996
Stuart S. Kaufman; Anil Dhawan; Angela K. Iverson; L. Snell; Cindy R. Brown; Carolyn K. Davis; Ira J. Fox; Thomas G. Heffron; Debra Sudan; Todd Pillen; Jon A. Vanderhoof; Alan N. Langnas
Journal of Pediatric Gastroenterology and Nutrition | 1995
Anil Dhawan; T A Seemayer; C Closkins; T G Gross; Byers W. Shaw; P R Mack