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Dive into the research topics where Anil M. Kumar is active.

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Featured researches published by Anil M. Kumar.


Analytical Biochemistry | 1992

Resolution of dihydroxyeicosanoates and of dihydroxyeicosatrienoates by chiral phase chromatography

Jorge H. Capdevila; Shouzou Wei; Anil M. Kumar; Jun Kobayashi; James R. Snapper; Darryl C. Zeldin; Rama K. Bhatt; John R. Falck

A chromatographic method is described for the direct enantiomeric characterization of 5,6-, 8,9-, 11,12-, and 14,15-vic-dihydroxyeicosatrienoic acids (DHETs), metabolites of the cytochrome P-450 arachidonate epoxygenase pathway, and of their corresponding saturated vic-dihydroxyeicosanoic acids. Following esterification, the individual methyl or pentafluorobenzyl esters are resolved by chiral-phase chromatography utilizing a Chiralcel OC or OD column. This methodology will find analytical and preparative applications since it is simple and efficient and preserves, intact, the diol functionality.


Archive | 2000

Manufacture of polyglutamate-therapeutic agent conjugates

Anil M. Kumar; J. Klein; Rama K. Bhatt; Edward Vawter


Archive | 2002

6-phenyl-n-phenyl-(1,3,5) -triazine-2,4-diamine derivatives and related compounds with lysophphosphatidic acid acyltransferase beta (lpaat-beta) inhibitory activity for use in the treatment of cancer

Rama K. Bhatt; Baoqing Gong; Feng Hong; Scott A. Jenkins; J. Peter Klein; Anil M. Kumar; John Tulinsky


Archive | 2007

Aryl triazines as LPAAT-β inhibitors and uses thereof

Rama K. Bhatt; Baoqing Gong; Feng Hong; Scott A. Jenkins; J. Peter Klein; Anil M. Kumar; John Tulinsky


Archive | 2004

Therapeutic compounds for inhibiting interleukin-12 signaling and methods for using same

J. Klein; Stephen J. Klaus; Anil M. Kumar; Baoqing Gong


Archive | 2000

Xanthine derivatives and analogs as cell signalling inhibitors

J. Peter Klein; Stephen J. Klaus; Anil M. Kumar; Baoqing Gong


Archive | 2004

Compounds having selective hydrolytic potentials

David Porubek; Anil M. Kumar; Charles R. Bredl; J. Peter Klein


Archive | 2004

Polyglutamate camptothecin conjugates

Anil M. Kumar; Peter Klein; Rama K. Bhatt; Edward Vawter


Archive | 2002

Derives de 6-phenyl-n-phenyl-(1,3,5)-triazine-2,4-diamine et composes apparentes ayant un effet inhibiteur de l'acide lysophosphatidique acyltransferase beta (lpaat-beta) et destines a etre utilises pour traiter le cancer

Rama K. Bhatt; Baoqing Gong; Feng Hong; Scott A. Jenkins; J. Peter Klein; Anil M. Kumar; John Tulinsky


Archive | 2000

Production de conjugues d'agents therapeutiques de polyglutamate

Anil M. Kumar; J. Peter Klein; Rama K. Bhatt; Edward Vawter

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Rama K. Bhatt

University of Texas Southwestern Medical Center

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Darryl C. Zeldin

National Institutes of Health

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John R. Falck

University of Texas Southwestern Medical Center

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