Anil Panmand
Takeda Pharmaceutical Company
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Publication
Featured researches published by Anil Panmand.
ACS Medicinal Chemistry Letters | 2017
Sujay Basu; Dinesh Barawkar; Vidya Ramdas; Minakshi Naykodi; Yogesh Shejul; Meena V. Patel; Sachin Thorat; Anil Panmand; K. Kashinath; Rajesh Bonagiri; Vandna Prasad; Ganesh Bhat; Azfar Quraishi; Sumit Chaudhary; Amol Magdum; Ashwinkumar V. Meru; Indraneel Ghosh; Ravi K. Bhamidipati; Amol A. Raje; Vamsi Madgula; Siddhartha De; Sreekanth R. Rouduri; Venkata Palle; Anita Chugh; Narayanan Hariharan; Kasim A. Mookhtiar
Adenosine A2A receptor (A2AAdoR) antagonism is a nondopaminergic approach to Parkinsons disease treatment that is under development. Earlier we had reported the therapeutic potential of 7-methoxy-4-morpholino-benzothiazole derivatives as A2AAdoR antagonists. We herein described a novel series of [1,2,4]triazolo[5,1-f]purin-2-one derivatives that displays functional antagonism of the A2A receptor with a high degree of selectivity over A1, A2B, and A3 receptors. Compounds from this new scaffold resulted in the discovery of highly potent, selective, stable, and moderate brain penetrating compound 33. Compound 33 endowed with satisfactory in vitro and in vivo pharmacokinetics properties. Compound 33 demonstrated robust oral efficacies in two commonly used models of Parkinsons disease (haloperidol-induced catalepsy and 6-OHDA lesioned rat models) and depression (TST and FST mice models).
European Journal of Medicinal Chemistry | 2017
Sujay Basu; Dinesh Barawkar; Vidya Ramdas; Yogesh Waman; Meena V. Patel; Anil Panmand; Sachin Thorat; Rajesh Bonagiri; Dilip Jadhav; Partha Mukhopadhyay; Vandna Prasad; B. Srinivasa Reddy; Arnab Goswami; Sandhya Chaturvedi; Suraj Menon; Azfar Quraishi; Indraneel Ghosh; Sushant Dusange; Shalini Paliwal; Abhay Kulkarni; Vikas Karande; Rhishikesh Thakre; Gaurav Bedse; Sreekanth R. Rouduri; Jayasagar Gundu; Venkata Palle; Anita Chugh; Kasim A. Mookhtiar
European Journal of Medicinal Chemistry | 2017
Sujay Basu; Dinesh Barawkar; Vidya Ramdas; Meena V. Patel; Yogesh Waman; Anil Panmand; Sachin Thorat; Minakshi Naykodi; Arnab Goswami; B. Srinivasa Reddy; Vandna Prasad; Sandhya Chaturvedi; Azfar Quraishi; Suraj Menon; Shalini Paliwal; Abhay Kulkarni; Vikas Karande; Indraneel Ghosh; Syed Mustafa; Siddhartha De; Vaibhav Jain; Ena Ray Banerjee; Sreekanth R. Rouduri; Venkata Palle; Anita Chugh; Kasim A. Mookhtiar
Archive | 2011
Dinesh Barawkar; Sujay Basu; Vidya Ramdas; Venkata P. Palle; Yogesh Waman; Meena V. Patel; Anil Panmand
Archive | 2011
Dinesh Barawkar; Sujay Basu; Vidya Ramdas; Minakshi Naykodi; Meena V. Patel; Yogesh Shejul; Sachin Thorat; Anil Panmand
Archive | 2010
Venkata P. Palle; Vidya Ramdas; Dinesh Barawkar; Sujay Basu; Summon Koul; Yogesh Waman; Meena V. Patel; Anil Panmand
Archive | 2016
Anil Deshpande; Dinesh Barawkar; Santosh Patil; Anil Panmand; Dilip Jadhav; Yogesh Waman; Bheemashankar Kulkarni; Takahiko Taniguchi
Archive | 2016
Dinesh Barawkar; Anil Deshpande; Santosh Patil; Yogesh Waman; Anil Panmand; Dilip Jadhav; Bheemashankar Kulkarni
Tetrahedron Letters | 2014
Goraksha Khose; Shailesh Shinde; Anil Panmand; Ravibhushan Kulkarni; Yogesh Munot; Anish Bandyopadhyay; Dinesh Barawkar; Santoshkumar N. Patil
Archive | 2011
Dinesh Barawkar; Sujay Basu; Vidya Ramdas; Venkata P. Palle; Yogesh Waman; Meena V. Patel; Anil Panmand
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Post Graduate Institute of Medical Education and Research
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