Anis Haddad

Skin metastases revealing a bilateral ovarian invasive micropapillary serous carcinoma.

Skin involvement is a late complication that rarely occurs in ovarian cancer patients. This event invariably carries a bad prognosis in the course of an advanced stage ovarian carcinoma which is usually of the conventional serous type. Micropapillary serous carcinoma (MPSC) was recently recognized as a distinct neoplasm that seems to be less aggressive than conventional serous ovarian carcinoma. Indeed, a few cases of stage IV MPSC have been reported. Herein, we describe an unusual case of ovarian invasive MPSC occurring in a young woman, particularly by its mode of presentation as multiple subcutaneous nodules that were subsequently diagnosed as metastatic lesions. This case demonstrates the potential of MPSC for aggressive clinical behaviour.

Diagnostic clinique et échographique des macrosomies fœtales supérieures à 4 500 g

Resume La macrosomie fœtale est une situation a risque fœto-maternel et demeure une preoccupation majeure des obstetriciens et echographistes. Le risque de complications est dependant du degre de macrosomie et de la qualite de prise en charge. La macrosomie fœtale superieure a 4 500 g touche environ 1,5 % des naissances, elle pose un probleme majeur du fait de la frequence des complications et de l’absence de facteurs predictifs fiables. Face a cette situation, les estimations clinique et echographique sont les deux principaux moyens a notre disposition pour predire le poids fœtal et constituent donc un element decisionnel important dans la prise en charge de ces macrosomies. En revanche, ces deux methodes sont grevees d’erreurs et d’imprecisions qui sont d’autant plus importantes que le poids fœtal est eleve. De plus des discordances entre la clinique (mesure de la hauteur uterine) et l’echographie sont possibles, d’autant plus qu’il s’agit d’une femme diabetique. Afin d’ameliorer la performance de l’echographie, differents indices et formules ont ete developpes avec une sensibilite et specificite variables. Dans cette mise au point les auteurs resument les avantages et les inconvenients de la clinique et des mesures echographiques dans la prediction de la macrosomie fœtale.

Pemphigoid Gestationis: A Case Report and Review of Literature

Pemphigoid gestationis is a rare autoimmune blistering disease specific to pregnancy. It is characterized by pruritic, urticarial plaques with development of tense vesicles and bullae within the lesions. Recurrence with subsequent pregnancies are often more severe and may be associated with miscarriages, prematurity, low birth weight and rarely fetal death. We report this case of pemphigoid gestationis in view of the importance of early diagnosis and treatment for prevention of fetal risk.

Takayasu's Arteritis and Pregnancy: A Case Report and Review of Literature

Introduction: Takayasus arteritis is a nonspecific incessant fiery vasculitis which wrecks huge vascular trunks (aorta and its branches and pneumonic supply routes). Its etiology is not yet explained. It prevalently influences young ladies when it is connected with pregnancy that makes pregnancy at danger due to duplicating maternal and fetal confusions. Objectives: The point of our work is to etudiate the effect of Takayasus infection on pregnancy; decide the effect of pregnancy on this illness and to propose a pragmatic driving for the prosperity maternal-fetal in the event that this affiliation. Observation: We report the instance of Ms. M.K matured 29 years, nulliparous third act, with a past filled with two restorative premature births. The patient is known Takayasus sickness quiet from 15 years, at present pregnant with spontaneous pregnancy and counseled surprisingly at 20 weeks of incubation. Our patient has a coarctation of the aorta with serious hypertension. The course of pregnancy was set apart by the diligence of unequal hypertension requiring three hostile to hypertensive medications, and afterward it was pre eclampsia. Concerning the baby; he was in extreme intrauterine development impediment more clear at 30 weeks incubation, requiring a nearby ultrasound checking. Amid the Doppler checking there has been a converse stream showing crisis labor by cesarean segment at 34 weeks. The quick postoperative and medium term outcomes were good. Conclusion: The event of pregnancy in a patient with Takayasus sickness is an uncommon circumstance that can be set apart by difficulties: pre-eclampsia, the intrauterine development hindrance, the shaky pulse, and heart disappointment. Enhancing maternal-fetal visualization requires a few suggestions

Devant cet impuberisme quels sont vos diagnostics

ResumeLes auteurs rapportent un tableau clinique atypique, celui d’un patient présentant un désordre du développement sexuel (46XY DDS). L’exploration a montré des taux de FSH et LH élevés, une testostéronémie basse, avec absence de gonades ainsi que tout dérivé des canaux de Müller et de Wolff à la laparoscopie.Les auteurs discutent les différentes possibilités diagnostiques pouvant correspondre à ce tableau clinique et insistent sur celui de syndrome de régression testiculaire embryonnaire, entité rare et originale.AbstractThe authors report a case of a 16-year-old Tunisian phenotypically female patient with an 46, XY karyotype. Serum assays showed high serum FSH and LH levels and low serum testosterone levels. Laparoscopic exploration was performed to distinguish between testicular feminization syndrome and gonadal dysgenesis. No gonads and no persistent Müllerian or Wolffian ducts were found.The authors suspected the diagnosis of embryonic testicular regression syndrome (TRS), a congenital condition in which the testes disappear during early embryonic development. A spectrum of pathological findings may be present, but few systematic descriptions have been reported in the literature.The authors describe a new case of suspected embryonic testicular regression syndrome and discuss the differential diagnoses.