Anish Jacob Cherian

Anaplastic Thyroid Carcinoma

Thyroid cancers are common world over. The majority are well-differentiated thyroid cancers which have a good prognosis. A minority of patients develop anaplastic thyroid cancer, an aggressive type of thyroid cancer with grave prognosis and limited treatment options. In order to improve outcomes for these patients the current area of research is in understanding the genetic and molecular pathogenesis of these cancers to facilitate targeted therapies. In this chapter, we review the epidemiology, clinicopathological features, investigations, treatment options and prognosis of anaplastic thyroid carcinomas.

Ectopic thymic parathyroid adenoma.

Eighty per cent of primary hyperparathyroidism cases are caused by parathyroid adenoma while nearly 16% of ectopic parathyroid adenomas have been found to be the aetiology.1 A 50-year-old man presented with pain in the back and knees for 4 years. He was initially evaluated elsewhere and was detected to have hypercalcaemia. No other investigations were done at the other facility. He was then evaluated in our institution for the persistence of hypercalcaemia and recently deranged renal function. His blood investigations revealed: …