Anja Thiessenhusen
Evonik Industries
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Publication
Featured researches published by Anja Thiessenhusen.
Angewandte Chemie | 2015
Alexander Dennig; Miriam Kuhn; Sebastian Tassoti; Anja Thiessenhusen; Stefan Gilch; Thomas Bülter; Thomas Haas; Mélanie Hall; Kurt Faber
The enzymatic oxidative decarboxylation of linear short-chain fatty acids (C4:0-C9:0) employing the P450 monooxygenase OleT, O2 as the oxidant, and NAD(P)H as the electron donor gave the corresponding terminal C3 to C8 alkenes with product titers of up to 0.93 g L(-1) and TTNs of >2000. Key to this process was the construction of an efficient electron-transfer chain employing putidaredoxin CamAB in combination with NAD(P)H recycling at the expense of glucose, formate, or phosphite. This system allows for the biocatalytic production of industrially important 1-alkenes, such as propene and 1-octene, from renewable resources for the first time.
Biospektrum | 2016
Alexander Dennig; Anja Thiessenhusen; Stefan Gilch; Thomas Haas; Mélanie Hall
Abstract1-Alkenes represent primary building blocks for the chemical industry. Here we show the development of a novel biosynthetic redox-cascade involving the P450 monooxygenase OleT and electron transfer proteins CamA and CamB to allow the biocatalytic synthesis of short chain alkenes such as propene or 1,4-pentadiene from fatty acids. The cascade is fully based on renewables and can be operated under mild reaction conditions as opposed to industrial alkene synthesis.
Archive | 2014
Steffen Schaffer; Mirja Wessel; Anja Thiessenhusen
Archive | 2011
Steffen Schaffer; Mirja Wessel; Anja Thiessenhusen; Nadine Stein
Archive | 2010
Liv Reinecke; Steffen Schaffer; Tim Koehler; Anja Thiessenhusen; Achim Marx; Markus Buchhaupt
Angewandte Chemie | 2015
Alexander Dennig; Miriam Kuhn; Sebastian Tassoti; Anja Thiessenhusen; Stefan Gilch; Thomas Bülter; Thomas Haas; Mélanie Hall; Kurt Faber
Archive | 2012
Steffen Schaffer; Anja Thiessenhusen; Mirja Wessel
Archive | 2012
Steffen Schaffer; Mirja Wessel; Anja Thiessenhusen; Nadine Stein
Archive | 2017
Anja Thiessenhusen; Stefan Gilch; Thomas Dr Blter; Thomas Haas; Mlanie Dr Hall; Kurt Faber; Alexander Dr Denning
Archive | 2016
Martin Demler; Anja Thiessenhusen; Simon Beck; Eva Eckl; Markus Maria Dr Ptter; Thomas Haas