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Dive into the research topics where Anja Thiessenhusen is active.

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Featured researches published by Anja Thiessenhusen.


Angewandte Chemie | 2015

Oxidative Decarboxylation of Short‐Chain Fatty Acids to 1‐Alkenes

Alexander Dennig; Miriam Kuhn; Sebastian Tassoti; Anja Thiessenhusen; Stefan Gilch; Thomas Bülter; Thomas Haas; Mélanie Hall; Kurt Faber

The enzymatic oxidative decarboxylation of linear short-chain fatty acids (C4:0-C9:0) employing the P450 monooxygenase OleT, O2 as the oxidant, and NAD(P)H as the electron donor gave the corresponding terminal C3 to C8  alkenes with product titers of up to 0.93 g L(-1) and TTNs of >2000. Key to this process was the construction of an efficient electron-transfer chain employing putidaredoxin CamAB in combination with NAD(P)H recycling at the expense of glucose, formate, or phosphite. This system allows for the biocatalytic production of industrially important 1-alkenes, such as propene and 1-octene, from renewable resources for the first time.


Biospektrum | 2016

Biotechnologische Herstellung terminaler Alkene und Diene

Alexander Dennig; Anja Thiessenhusen; Stefan Gilch; Thomas Haas; Mélanie Hall

Abstract1-Alkenes represent primary building blocks for the chemical industry. Here we show the development of a novel biosynthetic redox-cascade involving the P450 monooxygenase OleT and electron transfer proteins CamA and CamB to allow the biocatalytic synthesis of short chain alkenes such as propene or 1,4-pentadiene from fatty acids. The cascade is fully based on renewables and can be operated under mild reaction conditions as opposed to industrial alkene synthesis.


Archive | 2014

Cells, nucleic acids, enzymes and use thereof, and methods for the production of sophorolipids

Steffen Schaffer; Mirja Wessel; Anja Thiessenhusen


Archive | 2011

Cells and methods for producing rhamnolipids

Steffen Schaffer; Mirja Wessel; Anja Thiessenhusen; Nadine Stein


Archive | 2010

USE OF A PROTEIN HOMOLOGOUS TO A MEAB PROTEIN FOR INCREASING THE ENZYMATIC ACTIVITY OF A 3-HYDROXYCARBOXYLIC ACID-COA MUTASE

Liv Reinecke; Steffen Schaffer; Tim Koehler; Anja Thiessenhusen; Achim Marx; Markus Buchhaupt


Angewandte Chemie | 2015

Oxidative Decarboxylierung von kurzkettigen Fettsäuren zu 1‐Alkenen

Alexander Dennig; Miriam Kuhn; Sebastian Tassoti; Anja Thiessenhusen; Stefan Gilch; Thomas Bülter; Thomas Haas; Mélanie Hall; Kurt Faber


Archive | 2012

New cell capable of forming rhamnolipid compound, which is useful for the production of cosmetic, dermatological or pharmaceutical formulations, of plant protection formulations and of care and cleaning agents and surfactant concentrates

Steffen Schaffer; Anja Thiessenhusen; Mirja Wessel


Archive | 2012

Zellen und Verfahren zur Herstellung von Rhamnolipiden

Steffen Schaffer; Mirja Wessel; Anja Thiessenhusen; Nadine Stein


Archive | 2017

PRODUCCIÓN DE ALQUENOS

Anja Thiessenhusen; Stefan Gilch; Thomas Dr Blter; Thomas Haas; Mlanie Dr Hall; Kurt Faber; Alexander Dr Denning


Archive | 2016

MÉTODO QUE COMPRENDE UN CULTIVO CON UNA CONCENTRACIÓN RELATIVAMENTE BAJA DE OXÍGENO DISUELTO

Martin Demler; Anja Thiessenhusen; Simon Beck; Eva Eckl; Markus Maria Dr Ptter; Thomas Haas

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Kurt Faber

Graz University of Technology

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Achim Marx

Forschungszentrum Jülich

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