Ann-Marie Golden

Reduced Specificity of Autobiographical Memory and Depression: The Role of Executive Control

It has been widely established that depressed mood states and clinical depression, as well as a range of other psychiatric disorders, are associated with a relative difficulty in accessing specific autobiographical information in response to emotion-related cue words on an Autobiographical Memory Test (AMT; J. M. G. Williams & K. Broadbent, 1986). In 8 studies the authors examined the extent to which this relationship is a function of impaired executive control associated with these mood states and clinical disorders. Studies 1–4 demonstrated that performance on the AMT is associated with performance on measures of executive control, independent of depressed mood. Furthermore, Study 1 showed that executive control (as measured by verbal fluency) mediated the relationship between both depressed mood and a clinical diagnosis of eating disorder and AMT performance. Using a stratified sample in Study 5, the authors confirmed the positive association between depressed mood and impaired performance on the AMT. Studies 6–8 involved experimental manipulations of the parameters of the AMT designed to further indicate that reduced executive control is to a significant extent driving the relationship between depressed mood and AMT performance. The potential role of executive control in accounting for other aspects of the AMT literature is discussed.

Reduced Autobiographical Memory Specificity and Posttraumatic Stress: Exploring the Contributions of Impaired Executive Control and Affect Regulation

Reduced specificity of autobiographical memories retrieved to word cues on the Autobiographical Memory Test (AMT) is associated with increased posttraumatic stress in traumatized samples. Theoretical debates concerning the dominant influences on this effect have focused on affect regulation, whereby specific personal information is avoided more by those experiencing greater distress, versus compromised executive control, whereby increased distress is associated with an inability to set aside inappropriately general responses on the AMT. The present study compared these 2 views in a correlational design using a reversed version of the AMT (the AMT-R) for which trauma-exposed participants (N=36) had to generate general memories from the past and avoid specific memories. An emphasis on the role of affect regulation would predict that distress would be associated with reduced specificity (as in the standard AMT), whereas emphasis on the role of executive control would predict that this relationship would be reversed. The data supported the affect regulation account, with greater posttraumatic stress being associated with reduced memory specificity.

Levels of specificity of autobiographical memories and of biographical memories of the deceased in bereaved individuals with and without complicated grief.

Traumatized individuals experiencing posttraumatic stress have difficulty retrieving specific autobiographical memories to cue words on the Autobiographical Memory Test (AMT; J. M. G. Williams & K. Broadbent, 1986). This may represent a generalized, functional avoidance of the personal past. However, such individuals also often report specific intrusive memories of their trauma in the day-to-day. This raises the possibility that memories tied to the source of the persons distress are immune to this putative avoidance process. This was investigated in bereaved individuals with complicated grief (CG) who reported intrusive, specific memories from the life of their deceased loved one, and matched bereaved controls without CG. Participants performed the AMT and two Biographical Memory Tests (BMTs), cueing memories from the life of the deceased (BMT-Deceased) and from a living significant other (BMT-Living). To negative word cues, the CG group showed reduced specificity for the AMT and BMT-Living, relative to controls, but this effect was reversed on the BMT-Deceased. These data support the proposal that memories tied to the source of an individuals distress are immune to the processes that underlie the standard reduced specificity effect.

Is prolonged grief distinct from bereavement-related posttraumatic stress?

Prolonged grief disorder (PGD) (previously called complicated grief (CG)) is proposed as a distinct post loss syndrome, with its own core symptoms. A key issue concerning the diagnostic validity of PGD is whether it can reliably be distinguished from related psychiatric outcomes following bereavement. This study therefore sought to determine whether the core symptoms of PGD could be distinguished from those of bereavement-related anxiety, depression and posttraumatic stress disorder (PTSD). Data were derived from a community sample of 223 bereaved adults in Croatia. PGD symptomatology was measured using the Revised Inventory of Complicated Grief. Depression and anxiety symptoms were measured using the Beck Depression and Anxiety Inventories, respectively. The intrusion and avoidance symptoms of PTSD were assessed using the Revised Impact of Event Scale. The distinctiveness of the five symptom clusters was examined using principal component analysis (PCA). Symptoms of prolonged grief, depression, anxiety, PTSD-intrusion, and PTSD-avoidance clustered together into five distinct factors. These results support the phenomenological distinctiveness of prolonged grief symptoms, from those of bereavement-related anxiety, depression and, for the first time, PTSD.

Age Shall Not Weary Us: Deleterious Effects of Self-Regulation Depletion Are Specific to Younger Adults

Self-regulation depletion (SRD), or ego-depletion, refers to decrements in self-regulation performance immediately following a different self-regulation-demanding activity. There are now over a hundred studies reporting SRD across a broad range of tasks and conditions. However, most studies have used young student samples. Because prefrontal brain regions thought to subserve self-regulation do not fully mature until 25 years of age, it is possible that SRD effects are confined to younger populations and are attenuated or disappear in older samples. We investigated this using the Stroop color task as an SRD induction and an autobiographical memory task as the outcome measure. We found that younger participants (<25 years) were susceptible to depletion effects, but found no support for such effects in an older group (40–65 years). This suggests that the widely-reported phenomenon of SRD has important developmental boundary conditions casting doubt on claims that it represents a general feature of human cognition.

Reduced specificity of emotional autobiographical memories following self-regulation depletion.

The present study used a Color Stroop task, involving naming the ink colors of incongruous color words, to deplete self-regulation resources prior to retrieving a series of autobiographical memories to emotional and neutral cue words--the Autobiographical Memory Test (AMT). Control participants either read color words written in black ink or performed no task prior to the AMT. Difficulty accessing specific memories on the AMT has been shown to index key aspects of the onset and maintenance of depression and other emotional disorders. Our hypothesis that depleted participants would retrieve fewer specific memories to cues on the AMT relative to controls was supported, even when levels of depressed and anxious mood, an index of clinical depression, posttraumatic stress, and verbal intelligence were covaried. The results indicate that self-regulation depletion via a neutral, unrelated task can impact on emotion-related autobiographical memory processes that have been shown to be dysfunctional in emotionally disordered populations.

Method-of-Loci as a Mnemonic Device to Facilitate Access to Self-Affirming Personal Memories for Individuals With Depression

Depression impairs the ability to retrieve positive, self-affirming autobiographical memories. To counteract this difficulty, we trained individuals with depression, either in episode or remission, to construct an accessible mental repository for a preselected set of positive, self-affirming memories using an ancient mnemonic technique—the method-of-loci (MoL). Participants in a comparison condition underwent a similar training protocol where they chunked the memories into meaningful sets and rehearsed them (rehearsal). Both protocols enhanced memory recollection to near ceiling levels after 1 week of training. However, on a surprise follow-up recall test a further week later, recollection was maintained only in the MoL condition, relative to a significant decrease in memories recalled in the rehearsal group. There were no significant performance differences between those currently in episode and those in remission. The results support use of the MoL as a tool to facilitate access to self-affirming memories in those with depression.

Processing of emotional information in seasonal depression across different cognitive measures

This study examined memory for emotional material, endorsement of emotional adjectives, and negative attributional style (NAS) in seasonal affective disorder (SAD). SAD patients showed elevated NAS and increased endorsement of negative self-referent adjectives, but no memory bias for negative material, when compared with never-depressed controls. Longitudinal analyses revealed that none of these cognitive measures significantly predicted later symptom levels independent of initial symptom levels, in the SAD patients. The cross-sectional findings for adjective endorsement and memory were replicated in a second experiment. These data provide further evidence that depression-related memory effects in SAD are different from those found in nonseasonal depression. Accounts of these differences involving putative mood-repair processes and/or an absence of dysfunctional negative schemas in SAD are discussed.

Facets of Pejorative Self-Processing in Complicated Grief

OBJECTIVE Complicated grief (CG) has been proposed as a psychiatric response to bereavement distinct from established mood and anxiety disorder diagnoses. Little is known about the nature of cognitive-affective processing in CG, nor any similarities or differences compared with the processing profiles associated with other emotional disorders. Three studies therefore investigated 3 broad facets of negative self-processing associated with either elevated symptoms of, or diagnosis of, CG--namely, self-related attributions or blame, self-devaluation, and cognitions about the future self. METHOD These self-processing domains were assessed using a variety of self-report and scenario-based measures either linked specifically to the bereavement or more general in their focus. Study 1 used a correlational design in a community bereaved sample. Study 2 employed an extreme-groups approach looking at individuals high versus low in CG symptoms, and Study 3 compared those with a CG diagnosis to healthy bereaved controls. RESULTS The data revealed a profile of processing in CG characterized by significant relationships between CG symptoms or diagnosis and both self-devaluation and negative self-related cognitions about the future, but the data provided no support for a similar relationship with negative self-related attributions. CONCLUSIONS These findings extend our understanding of self-related cognitive processing in CG. They also suggest that CG is characterized by a cognitive-affective processing profile that is distinct from that associated with other disorders, notably major depression, in the literature. This has potential implications for the psychological treatment of CG and for its nosological status as a post-loss syndrome distinct from depression.

Anxiety and judgements about emotional events in children and adolescents

Research with clinically anxious adults has revealed that they estimate future negative events as far more likely to occur, relative to healthy controls. In addition, anxious adults estimate that such events are more likely to happen to themselves than to others. Previous research with anxious children and adolescents, in contrast, has revealed no increased probability estimates for negative events, relative to controls, and the events were rated as more likely to happen to others than to the self. The present study followed up these discrepant findings by investigating probability estimates for future negative events in children and adolescents with high and low levels of self-reported trait anxiety but who had no reported history of emotional disorder. The results revealed a significant difference between the two groups with respect to their overall probability estimates for negative events, the high anxious group estimating that negative events were more likely to happen than the low anxious group. These findings are consistent with the results using adult clinical subjects and support the suggestion that previous differences between the adult and developmental literature are a function of non-normative performance specifically in clinically anxious younger participants.