Anna C. F. Ruckert
Medical College of Wisconsin
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Featured researches published by Anna C. F. Ruckert.
In Vitro Cellular & Developmental Biology – Plant | 1970
Roland A. Pattillo; Robert O. Hussa; E. Delfs; John C. Garancis; R. Bernstein; Anna C. F. Ruckert; W. Y. Huang; G. O. Gey; Richard F. Mattingly
SummaryAn internal control mechanism capable of controlling gonadotrophic hormone secretion in the human trophoblast has been identified by incubation of an established cell line with a precursor of progesterone.Biological, biochemical, and electron microscopic findings verify inhibition of gonadotrophic hormone synthesis, depletion of glycogen, activation of phosphorylase, the glycogen-metabolizing enzyme, and ultrastructural appearance of liquid-containing cytoplasmic granules in single cells, indicative of steroid synthesis.
American Journal of Obstetrics and Gynecology | 1979
Roland A. Pattillo; Anna C. F. Ruckert; Michael T. Story; Richard F. Mattingly
Tumor immunology studies have been utilized for development of a blocking factor assay for therapy monitoring in ovarian cancer. The blocking factor index was defined as the arithmetic difference between assays conducted in the presence and absence of the patients serum compared to incubations with normal control lymphocytes. Eighteen advanced ovarian epithelial malignancies have shown blocking factor activity during treatment. Blocking factor has abated in eight patients whose clinical disease completely regressed. Chemotherapy was discontinued after 18 to 24 months. In 10 patients, blocking factor persisted and chemotherapy has been continued. Some of these patients showed decreasing blocking factor; others have shown increases, which led to death due to disseminated disease in four cases. Blocking factor activity was found to correlate with tumor growth.
Oncology | 1986
Robert O. Hussa; Roland A. Pattillo; Anna C. F. Ruckert; Martha L. Rinke; Joseph P. Cortesi; Henry G. Fein
This study was aimed at optimizing large-scale roller bottle culture conditions for CaSki human cervical carcinoma cells, to produce ectopic hCG beta-like material in quantities sufficient for subsequent characterization studies. Several cell culture techniques contributed to the achievement of this goal: (1) use of serum-free culture medium; (2) use of intermittent recovery periods in presence of serum; and (3) ultrafiltration of the serum-free medium pool for initial concentration of 100-fold.
The Journal of Clinical Endocrinology and Metabolism | 1978
Robert O. Hussa; Roland A. Pattillo; Anna C. F. Ruckert; Keith W. Scheuermann
Endocrinology | 1979
Roland A. Pattillo; Robert O. Hussa; Anna C. F. Ruckert; James W. Kurtz; Jimmie M. Cade; Martha L. Rinke
Cancer Research | 1979
Roland A. Pattillo; Michael T. Story; Anna C. F. Ruckert
The Journal of Nuclear Medicine | 1995
Roland A. Pattillo; B. D. Collier; Hussein M. Abdel-Dayem; Kutlan Ozker; Charles R. Wilson; Anna C. F. Ruckert; K. Hamilton
Journal of the National Cancer Institute | 1970
Robert O. Hussa; Roland A. Pattillo; John C. Garancis; Anna C. F. Ruckert; Richard F. Mattingly
The Journal of Clinical Endocrinology and Metabolism | 1981
Roland A. Pattillo; Anna C. F. Ruckert; Stuart D. Wilson; Robert O. Hussa; Richard W. Gray; Jacob Lemann
Gynecologic Oncology | 1991
Roland A. Pattillo; Hussein M. Abdel-Dayem; Anna C. F. Ruckert; Kutlan Ozker; Charles R. Wilson; Karen Hamilton; B. David Collier