Anna Janocha

Assessment of body surface potential mapping in VDT-Operators

Computer is a genius invention that has made human work more efficient. In spite of undeniable benefits, everyday long-term contact with computer screens is an occupational risk, which induces various undesirable health consequences. Exposure of the VDT-operators to the harmful occupational factors may lead to functional disorders like arrhythmia. BSPM is a diagnostic method enabling global and precise sampling the heart potentials all over the thoracic surface owing to the large number of recording electrodes. Data collected from 87 ECG waveforms is graphically presented as the body surface maps of various formats. Non-dipolar distribution of QRST isointegral maps reflects a heterogeneity of the refractory periods of the ventricles, which is supposed to account for creating a substrate for malignant and life- threatening arrhythmias. This method can be a specific indicator of the increased risk of severe ventricular arrhythmias occurring prior to abnormalities detectable on the standard 12-lead ECG recordings.

Inhibition of cysteine peptidase activity in ascitic fluid in pancreatic cancer patients.

The works objective is to answer the question whether there is any possibility of activity inhibition of cysteine peptidases inhibitors playing an important role in key processes accompanying cancer formation, including pancreas. There is a justified speculation that specific inhibitors of these enzymes may inhibit development of cancer processes by inhibiting their activity. In vitro studies confirmed that these enzymes in ascitic fluid were inhibited with egg whites inhibitors even to 90% of their original activity.