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Featured researches published by Anna Winkvist.


Social Science & Medicine | 2000

Candies in hell: women's experiences of violence in Nicaragua

Mary Ellsberg; Rodolfo Peña; Andre s Herrera; Jerker Liljestrand; Anna Winkvist

The aim of this study was to describe the characteristics of domestic violence against women in León, Nicaragua. A survey was carried out among a representative sample of 488 women between the ages of 15-49. The physical aggression sub-scale of the Conflict Tactics Scale was used to identify women suffering abuse. In-depth interviews with formerly battered women were performed and narratives from these interviews were analysed and compared with the survey data. Among ever-married women 52% reported having experienced physical partner abuse at some point in their lives. Median duration of abuse was 5 years. A considerable overlap was found between physical, emotional and sexual violence, with 21% of ever-married women reporting all three kinds of abuse. Thirty-one percent of abused women suffered physical violence during pregnancy. The latency period between the initiation of marriage or cohabitation and violence was short, with over 50% of the battered women reporting that the first act of violence act took place within the first 2 years of marriage. Significant, positive associations were found between partner abuse and problems among children, including physical abuse. Both the survey data and the narrative analysis pointed to extreme jealousy and control as constant features of the abusive relationship. Further, the data indicate that battered women frequently experience feelings of shame, isolation and entrapment which, together with a lack of family and community support, often contribute to womens difficulty in recognizing and disengaging from a violent relationship. These findings are consistent with theoretical conceptualisations of domestic violence developed in other countries, suggesting that, to a large degree, womens experiences of violence transcend specific cultural contexts.


Health Policy | 2000

Gender and tuberculosis control Perspectives on health seeking behaviour among men and women in Vietnam

Eva Johansson; Nguyen Hoang Long; Vinod K. Diwan; Anna Winkvist

This study explores the perspectives of tuberculosis patients on which factors influenced their health seeking behaviour, with special reference to gender differentials in terms of delays in health seeking. In 1996, a multi-disciplinary research team carried out 16 focus group discussions. The study was done in four districts in Vietnam, both in the south and north of the country and in urban and rural areas. Qualitative analysis of data was performed following general principles of modified grounded theory technique. Participants in the focus groups described three main factors as contributing to delay in health seeking. These were fear of social isolation, economic constraints and inadequate staff attitudes and poor quality of health services. A model illustrating different factors influencing health seeking was elaborated and served as a basis for discussion of the findings. The main factor contributing to delay among women was described as fear of social isolation from the family or the community. Stigma was described as closely related to contextual factors such as gender-roles, socio-economic status and level of education and seemed to be mediated via denial and concealment of tuberculosis diagnosis and disease, thus causing delay. The main factor contributing to delay among men was described as fear of individual costs of diagnosis and treatment. Staff attitudes and quality of health service facilities were described as not always corresponding to peoples expectations of appropriate health services. Women saw themselves and were seen by others as being more sensitive than men to poor service conditions and staff attitudes. A typical feature of the described health seeking behaviour of men was that they neglected symptoms until the disease reached a serious stage, by which time they tended to go directly to public health services without first visiting private health practitioners. Women, on the other hand, were described as having a tendency to seek out private services and practice self-medication before seeking care at public services. In conclusion, there is a need for better understanding of behavioural factors and for developing strategies, that take these into account. Health workers need to better understand gender and social aspects of tuberculosis control, particularly aspects that influence the likelihood for achieving equity in diagnosis and cure.


International Journal of Cancer | 1999

Fatty-acid composition in serum phospholipids and risk of breast cancer: an incident case-control study in Sweden.

Véronique Chajès; Kerstin Hultén; Anne Linda Van Kappel; Anna Winkvist; Rudolf Kaaks; Göran Hallmans; Per Lenner; Elio Riboli

The study of the relationship between dietary intake of fatty acids and the risk of breast cancer has not yielded definite conclusions with respect to causality, possibly because of methodological issues inherent to nutritional epidemiology. To evaluate the hypothesis of possible protection of n‐3 polyunsaturated fatty acids (PUFA) against breast cancer in women, we examined the fatty‐acid composition of phospholipids in pre‐diagnostic sera of 196 women who developed breast cancer, and of 388 controls matched for age at recruitment and duration of follow‐up, in a prospective cohort study in Umeå, northern Sweden. Individual fatty acids were measured as a percentage of total fatty acids, using capillary gas chromatography. Conditional logistic‐regression models showed no significant association between n‐3 PUFA and breast‐cancer risk. In contrast, women in the highest quartile of stearic acid had a relative risk of 0.49 (95% confidence interval, 0.22–1.08) compared with women in the lowest quartile (trend p = 0.047), suggesting a protective role of stearic acid in breast‐cancer risk. Besides stearic acid, women in the highest quartile of the 18:0/18:1 n‐9c ratio had a relative risk of 0.50 (95% confidence interval, 0.23–1.10) compared with women in the lowest quartile (trend p = 0.064), suggesting a decrease in breast‐cancer risk in women with low activity of the enzyme delta 9‐desaturase (stearoyl CoA desaturase), which may reflect an underlying metabolic profile characterized by insulin resistance and chronic hyper‐insulinemia. Int. J. Cancer 83:585–590, 1999.


Health Policy | 2001

Fear and social isolation as consequences of tuberculosis in VietNam: a gender analysis

Nguyen Hoang Long; Eva Johansson; Vinod K. Diwan; Anna Winkvist

SETTING The study was conducted in four districts in different regions of Vietnam. OBJECTIVE To describe the socio-economic consequences of tuberculosis (TB) in Vietnam with special reference to gender differentials concerning social stigma and isolation. DESIGN Sixteen focus group discussions were carried out with men and women, TB patients and non-TB participants. Data was analysed using modified grounded theory technique. RESULTS Generally, the participants had good knowledge about TB. However, knowledge and practice were not closely related in the sense that most non-TB participants perceived that TB can be successfully cured, while patients were seriously shocked when they were told that they had TB. Male patients often worried about economic-related problems, while female patients worried about social consequences of the disease. Both in the family and the community, isolation could be subtle, but it could also be obvious and had a tendency to continue much longer than medically justified. CONCLUSION Information on stigma and isolation due to TB and gender differences is important for understanding patient dynamics and its effects on the disease. Tuberculosis control programmes need better understanding of the gender differences in attitudes and beliefs to improve case-detection and treatment outcome.


Journal of the National Cancer Institute | 2012

Circulating Carotenoids and Risk of Breast Cancer: Pooled Analysis of Eight Prospective Studies

A. Heather Eliassen; Sara J. Hendrickson; Louise A. Brinton; Julie E. Buring; Hannia Campos; Qi Dai; Joanne F. Dorgan; Adrian A. Franke; Yu-Tang Gao; Marc T. Goodman; G. Hallmans; Kathy J. Helzlsouer; Judy Hoffman-Bolton; Kerstin Hultén; Howard D. Sesso; Anne L. Sowell; Rulla M. Tamimi; Paolo Toniolo; Lynne R. Wilkens; Anna Winkvist; Anne Zeleniuch-Jacquotte; Wei Zheng; Susan E. Hankinson

BACKGROUND Carotenoids, micronutrients in fruits and vegetables, may reduce breast cancer risk. Most, but not all, past studies of circulating carotenoids and breast cancer have found an inverse association with at least one carotenoid, although the specific carotenoid has varied across studies. METHODS We conducted a pooled analysis of eight cohort studies comprising more than 80% of the worlds published prospective data on plasma or serum carotenoids and breast cancer, including 3055 case subjects and 3956 matched control subjects. To account for laboratory differences and examine population differences across studies, we recalibrated participant carotenoid levels to a common standard by reassaying 20 plasma or serum samples from each cohort together at the same laboratory. Using conditional logistic regression, adjusting for several breast cancer risk factors, we calculated relative risks (RRs) and 95% confidence intervals (CIs) using quintiles defined among the control subjects from all studies. All P values are two-sided. RESULTS Statistically significant inverse associations with breast cancer were observed for α-carotene (top vs bottom quintile RR = 0.87, 95% CI = 0.71 to 1.05, P(trend) = .04), β-carotene (RR = 0.83, 95% CI = 0.70 to 0.98, P(trend) = .02), lutein+zeaxanthin (RR = 0.84, 95% CI = 0.70 to 1.01, P(trend) = .05), lycopene (RR = 0.78, 95% CI = 0.62 to 0.99, P(trend) = .02), and total carotenoids (RR = 0.81, 95% CI = 0.68 to 0.96, P(trend) = .01). β-Cryptoxanthin was not statistically significantly associated with risk. Tests for heterogeneity across studies were not statistically significant. For several carotenoids, associations appeared stronger for estrogen receptor negative (ER(-)) than for ER(+) tumors (eg, β-carotene: ER(-): top vs bottom quintile RR = 0.52, 95% CI = 0.36 to 0.77, P(trend) = .001; ER(+): RR = 0.83, 95% CI = 0.66 to 1.04, P(trend) = .06; P(heterogeneity) = .01). CONCLUSIONS This comprehensive prospective analysis suggests women with higher circulating levels of α-carotene, β-carotene, lutein+zeaxanthin, lycopene, and total carotenoids may be at reduced risk of breast cancer.


American Psychologist | 1999

DOMESTIC VIOLENCE AND EMOTIONAL DISTRESS AMONG NICARAGUAN WOMEN: RESULTS FROM A POPULATION-BASED STUDY

Mary Ellsberg; Trinidad Caldera; Andrés Herrera; Anna Winkvist; Gunnar Kullgren

This study aimed to measure the prevalence of emotional distress among women in Leon Nicaragua and to identify risk factors for emotional distress with special reference to wife abuse. A survey was performed among a representative sample of women aged 15-49. Among ever-married women 20% were classified as experiencing emotional distress at the time of the interview and 52% reported physical partner abuse at some point in their lives. Women reporting abuse were six times more likely to experience emotional distress. An estimated 70% of all cases of emotional distress found among ever-married women were attributable to wife abuse. The study underscores the need to improve screening and care for battered women within mental health services in Nicaragua. (authors)


Social Science & Medicine | 2000

God should give daughters to rich families only: attitudes towards childbearing among low-income women in Punjab, Pakistan.

Anna Winkvist; Humaira Zareen Akhtar

We evaluated perceptions and experiences of bearing sons and daughters among 42 women in Punjab, Pakistan, with special emphasis on son preference, changes in womens status within the marital family and resulting health effects. Data were collected through repeated, in-depth interviews in Urdu or Punjabi in an urban area in Lahore and a village 40 km. outside of Lahore. For triangulation purposes, four focus group discussions were performed with additional women, as well as in-depth interviews with eight mothers-in-law, three traditional practitioners and three medical practitioners. In general, these women felt that they had limited control over their lives, and this was exemplified by early marriages, high expectations on newly wed women to conceive and poor access to contraceptives. Women frequently expressed a strong preference for sons, mostly for economic reasons, reflecting womens subordinate position in society and the low economic value placed on womens work. Mothers of sons mainly discussed health problems during pregnancy and health effects of repeated childbearing. Mothers of daughters and women without children spoke of harassment in the family as well as in society. The results should be of importance in the public health planning in Pakistan as well as for those engaged in womens health issues internationally.


AIDS | 2000

High AIDS awareness may cause tuberculosis patient delay: results from an HIV epidemic area, Thailand.

Jintana Ngamvithayapong; Anna Winkvist; Vinod K. Diwan

ObjectiveTo elicit community perceptions about tuberculosis (TB) and the behaviour of TB patients in an area where significant public health attention has been focused on AIDS. SettingChiang Rai, Thailand, the epicentre of HIV/AIDS in this country. DesignEleven focus group sessions with a cross-section of the population. ParticipantsHealth centre staff, community members, persons having HIV, TB patients (with and without HIV infection), and male injecting drug users; five female groups and six male groups. ResultPeople had good knowledge of AIDS but they knew little about TB. Only a few female patients, whose husbands had died of TB and AIDS, recognized their symptoms as TB and immediately sought care. People defined persons losing weight, having fever and cough as AIDS rather than TB. This resulted in delay in seeking care and non-adherence to TB treatment in some patients who suspected they had AIDS, and feared AIDS detection. Most HIV-negative TB patients were also suspected by their relatives and neighbours of having AIDS. Most participants, except HIV-positive females, believed TB to be curable. Although less than AIDS, the community stigmatized TB patients because of it being contagious and easily transmitted through exhalations, foods and drinks and closeness to TB patients. ConclusionIn HIV/AIDS high endemic situation, increased awareness and stigmatization of AIDS and inadequate knowledge of TB can result in delay in seeking TB care and in treatment non-adherence.


Cancer Causes & Control | 2001

Carotenoids, alpha-tocopherols, and retinol in plasma and breast cancer risk in northern Sweden.

Kerstin Hultén; Anne Linda Van Kappel; Anna Winkvist; Rudolf Kaaks; Göran Hallmans; Per Lenner; Elio Riboli

AbstractObjective: Using a nested case–referent design we evaluated the relationship between plasma levels of six carotenoids, alpha-tocopherol, and retinol, sampled before diagnosis, and later breast cancer risk. Methods: In total, 201 cases and 290 referents were selected from three population-based cohorts in northern Sweden, where all subjects donated blood samples at enrolment. All blood samples were stored at −80 °C. Cases and referents were matched for age, age of blood sample, and sampling centre. Breast cancer cases were identified through the regional and national cancer registries. Results: Plasma concentrations of carotenoids were positively intercorrelated. In analysis of three cohorts as a group none of the carotenoids was found to be significantly related to the risk of developing breast cancer. Similarly, no significant associations between breast cancer risk and plasma levels of α-tocopherol or retinol were found. However, in postmenopausal women from a mammography cohort with a high number of prevalent cases, lycopene was significantly associated with a decreased risk of breast cancer. A significant trend of an inverse association between lutein and breast cancer risk was seen in premenopausal women from two combined population-based cohorts with only incident cases. A non-significant reduced risk with higher plasma α-carotene was apparent throughout all the sub-analyses. Conclusion: In conclusion, no significant associations were found between plasma levels of carotenoids, α-tocopherol or retinol and breast cancer risk in analysis of three combined cohorts. However, results from stratified analysis by cohort membership and menopausal status suggest that lycopene and other plasma-carotenoids may reduce the risk of developing breast cancer and that menopausal status has an impact on the mechanisms involved.


Qualitative Health Research | 2002

Trust and Transparency in Human Encounters in Tuberculosis Control: Lessons Learned from Vietnam

Eva Johansson; Anna Winkvist

The purpose of this study was to elucidate understanding of mechanisms of the tuberculosis sickness trajectory in Vietnam. In-depth interviews with 24 TB patients and 16 health care providers involved in TB care were concurrently conducted, coded, and analyzed according to the grounded theory method. A need for quality interaction based on transparency and trust among patient, family, society, and provider was observed. Providers lacked an awareness of differences between male and female patients with regard to social situation and support. In particular, female patients needed social support, as they received less support from their families than men did. A need for active intervention to decrease social isolation and increase social support was more pronounced in families with a female TB patient.

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