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Dive into the research topics where Anton Simorov is active.

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Featured researches published by Anton Simorov.


Annals of Surgery | 2012

Laparoscopic colon resection trends in utilization and rate of conversion to open procedure: a national database review of academic medical centers.

Anton Simorov; Abhijit Shaligram; Valerie Shostrom; Eugene Boilesen; Jon S. Thompson; Dmitry Oleynikov

Objective:This study aims to examine trends of utilization and rates of conversion to open procedure for patients undergoing laparoscopic colon resections (LCR). Methods:This study is a national database review of academic medical centers and a retrospective analysis utilizing the University HealthSystem Consortium administrative database—an alliance of more than 300 academic and affiliate hospitals. Results:A total of 85,712 patients underwent colon resections between October 2008 and December 2011. LCR was attempted in 36,228 patients (42.2%), with 5751 patients (15.8%) requiring conversion to an open procedure. There was a trend toward increasing utilization of LCR from 37.5% in 2008 to 44.1% in 2011. Attempted laparoscopic transverse colectomy had the highest rate of conversion (20.8%), followed by left (20.7%), right (15.6%), and sigmoid (14.3%) colon resections. The rate of utilization was highest in the Mid-Atlantic region (50.5%) and in medium- to large-sized hospitals (47.0%–49.0%).Multivariate logistic regression has shown that increasing age [odds ratio (OR) = 4.8, 95% confidence interval (CI) = 3.6–6.4], male sex (OR = 1.2, 95% CI = 1.1–1.3), open as compared with laparoscopic approach (OR = 2.6, 95%, CI = 2.3–3.1), and greater severity of illness category (OR = 27.1, 95% CI = 23.0–31.9) were all associated with increased mortality and morbidity and prolonged length of hospital stay. Conclusions:There is a trend of increasing utilization of LCR, with acceptable conversion rates, across hospitals in the United States over the recent years. When feasible, attempted LCR had better outcomes than open colectomy in the immediate perioperative period.


American Journal of Surgery | 2013

Emergent cholecystostomy is superior to open cholecystectomy in extremely ill patients with acalculous cholecystitis: a large multicenter outcome study

Anton Simorov; Ajay Ranade; Jeremy Parcells; Abhijit Shaligram; Valerie Shostrom; Eugene Boilesen; Matthew R. Goede; Dmitry Oleynikov

BACKGROUND Morbidity and mortality are very high for critically ill patients who develop acute acalculous cholecystitis (AAC). The aim of this study was to compare outcomes in extremely ill patients with AAC treated with percutaneous cholecystostomy (PC), laparoscopic cholecystectomy (LC), or open cholecystectomy (OC), which were also analyzed together in the LC-plus-OC (LO) group. METHODS Discharge data from the University HealthSystem Consortium database were accessed using International Classification of Diseases codes. The University HealthSystem Consortiums Clinical Data Base/Resource Manager allows member hospitals to compare patient-level, risk-adjusted outcomes. Multivariate regression models for extremely ill patients undergoing PC or LO for the diagnosis of AAC were created and analyzed. RESULTS A total of 1,725 extremely ill patients were diagnosed with AAC between October 2007 and June 2011. Patients undergoing PC (n = 704) compared with the LO group (n = 1,021) showed decreased morbidity (5.0% with PC vs 8.0% with LO, P < .05), fewer intensive care unit admissions (28.1% with PC vs 34.6% with LO, P < .05), decreased length of stay (7 days with PC vs 8 days with LO, P < .05), and lower costs (


Surgical Endoscopy and Other Interventional Techniques | 2012

Review of surgical robotics user interface: what is the best way to control robotic surgery?

Anton Simorov; R. Stephen Otte; Courtni M. Kopietz; Dmitry Oleynikov

40,516 with PC vs


American Journal of Surgery | 2014

Alvimopan reduces length of stay and costs in patients undergoing segmental colonic resections: results from multicenter national administrative database

Anton Simorov; Jon S. Thompson; Dmitry Oleynikov

53,011 with LO, P < .05). Although perioperative outcomes of PC compared with LC were statistically similar, PC had lower costs compared with LC (


American Journal of Surgery | 2011

Comparison of perioperative outcomes in patients undergoing laparoscopic versus open abdominoperineal resection

Anton Simorov; Jason F. Reynoso; Oleg Dolghi; Jon S. Thompson; Dmitry Oleynikov

40,516 vs 51,596, P < .005). Multivariate regression analysis showed that LC (n = 822), compared with OC (n = 199), had lower mortality (odds ratio [OR], .3; 95% confidence interval [CI], .1 to .6), lower morbidity (OR, .4; 95% CI, .2 to .7), reduced intensive care unit admission (OR, .3; 95% CI, .2 to .5), and similar 30-day readmission rates (OR, 1.0; 95% CI, .6 to 1.5). Also, decreased length of stay (7 days with LC vs 8 days with OC) and costs (


American Journal of Surgery | 2012

Do you need a computed tomographic scan to evaluate suspected appendicitis in young men: an administrative database review

Abhijit Shaligram; Pradeep K. Pallati; Anton Simorov; Avishai Meyer; Dmitry Oleynikov

51,596 with LC vs


Surgical Endoscopy and Other Interventional Techniques | 2017

Sleeve gastrectomy and anti-reflux procedures.

Christopher Crawford; Kyle Gibbens; Daniel Lomelin; Crystal Krause; Anton Simorov; Dmitry Oleynikov

61,407 with OC) were observed, with a 26% conversion rate to an open procedure. CONCLUSIONS On the basis of this experience, extremely ill patients with AAC have superior outcomes with PC. LC should be performed in patients in whom the risk for conversion is low and in whom medical conditions allow. These results show PC to be a safe and cost-effective bridge treatment strategy with perioperative outcomes superior to those of OC.


Surgical Endoscopy and Other Interventional Techniques | 2012

How does the robot affect outcomes? A retrospective review of open, laparoscopic, and robotic Heller myotomy for achalasia

Abhijit Shaligram; Jayaraj Unnirevi; Anton Simorov; Vishal Kothari; Dmitry Oleynikov

BackgroundAs surgical robots begin to occupy a larger place in operating rooms around the world, continued innovation is necessary to improve our outcomes.MethodsA comprehensive review of current surgical robotic user interfaces was performed to describe the modern surgical platforms, identify the benefits, and address the issues of feedback and limitations of visualization.ResultsMost robots currently used in surgery employ a master/slave relationship, with the surgeon seated at a work-console, manipulating the master system and visualizing the operation on a video screen. Although enormous strides have been made to advance current technology to the point of clinical use, limitations still exist. A lack of haptic feedback to the surgeon and the inability of the surgeon to be stationed at the operating table are the most notable examples. The future of robotic surgery sees a marked increase in the visualization technologies used in the operating room, as well as in the robots’ abilities to convey haptic feedback to the surgeon. This will allow unparalleled sensation for the surgeon and almost eliminate inadvertent tissue contact and injury.ConclusionsA novel design for a user interface will allow the surgeon to have access to the patient bedside, remaining sterile throughout the procedure, employ a head-mounted three-dimensional visualization system, and allow the most intuitive master manipulation of the slave robot to date.


Surgical Endoscopy and Other Interventional Techniques | 2012

Trends in adolescent bariatric surgery evaluated by UHC database collection

Pradeep K. Pallati; Shelby L. Buettner; Anton Simorov; Avishai Meyer; Abhijit Shaligram; Dmitry Oleynikov

BACKGROUND Alvimopan (Entereg), a peripherally acting mu-opioid receptor antagonist, has been shown to expedite recovery of bowel function after colon resection surgery. Most data are available from industry-sponsored trials. This study aims to evaluate the clinical impact of this drug on perioperative outcomes and costs in patients undergoing segmental colonic resection for diverticular disease. METHODS A large administrative database maintained by the University Health System Consortium, an alliance of over 200 academic and affiliate hospitals, was queried from 2008 to 2011. International Classification of Diseases, 9th Revision, Clinical Modification codes for segmental colon resection because of diverticular disease were used to identify 2 matched cohorts of adult patients. University Health System Consortiums clinical resource manager was used to access pharmacy data and compare it with patient outcomes. RESULTS Five thousand two hundred ninety-nine patients met the above criteria. Four hundred thirty-eight patients received alvimopan and 4,861 did not. Regardless of laparoscopic or open approach, alvimopan significantly improved the postoperative length of stay (4.43 ± 2.02 vs 5.92 ± 3.79, P < .0001), cost (9,974 ± 4,077 vs 11,303 ± 6,968, P < .0001), and intensive care unit admission rate (1.83% vs 7.20%, P < .05), with no significant difference in mortality (.0% vs .19%, P = 1.000), morbidity (5.93% vs 8.39%, P = .08), or 30-day readmission rate (4.40% vs 4.63%, P = .90). CONCLUSIONS Alvimopan significantly reduced length of stay, days in the intensive care unit, and hospital cost for patients undergoing colonic segmental resections. Unlike some previously reported studies, we also observed a significant reduction in the length of stay in patients undergoing laparoscopic colectomies who received the drug. Alvimopan may reduce total healthcare costs if used as part of a best care practice model for colon resections.


Surgical Endoscopy and Other Interventional Techniques | 2014

How does robotic anti-reflux surgery compare with traditional open and laparoscopic techniques: a cost and outcomes analysis

Benjamin Owen; Anton Simorov; Andy Siref; Valerie Shostrom; Dmitry Oleynikov

BACKGROUND The aim of this study was to retrospectively compare the outcomes of laparoscopic abdominoperineal resection (APR) and open APR. METHODS A multicenter, retrospective analysis was performed. The University HealthSystem Consortium database was accessed and searched for International Classification of Diseases, Ninth Revision, codes between October 2008 and January 2010. Discharge data were collected on patients undergoing laparoscopic APR and open APR. RESULTS Six hundred sixty-seven patients underwent laparoscopic APR, and 2,443 underwent open APR. When lower risk patient groups with minor or moderate severity of illness were compared, laparoscopic APR showed lower morbidity, reduced length of stay, reduced cost, and reduced incidence of intensive care unit admission. Comparative analysis showed no significant difference in mortality rate or 30-day readmission. When higher risk patients were compared, there were significantly reduced costs and reduced incidence of intensive care unit cases in the laparoscopic group. CONCLUSIONS Patients undergoing laparoscopic APR had overall superior perioperative outcomes compared with those undergoing open APR. Laparoscopic APR demonstrates excellent perioperative outcomes in appropriately selected patients.

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Dmitry Oleynikov

University of Nebraska Medical Center

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Abhijit Shaligram

University of Nebraska Medical Center

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Valerie Shostrom

University of Nebraska Medical Center

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Eugene Boilesen

University of Nebraska Medical Center

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Pradeep K. Pallati

Creighton University Medical Center

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Avishai Meyer

University of Nebraska Medical Center

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Carl Tadaki

Memorial Hospital of South Bend

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Daniel Lomelin

University of Nebraska Medical Center

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Ajay Ranade

University of Nebraska Medical Center

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Jon S. Thompson

University of Nebraska Medical Center

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