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Dive into the research topics where Antonio Fiorentino is active.

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Featured researches published by Antonio Fiorentino.


Phytochemistry | 1998

Antialgal compounds from Zantedeschia aethiopica

Marina Della Greca; Maria Ferrara; Antonio Fiorentino; Pietro Monaco; Lucio Previtera

Two cycloartane triterpenes and 10 sterols present in Zantedeschia aethiopica along with three lignans and 10 phenylpropanoids were identified by spectroscopic means. 3-(4-hydroxy-3-methoxy)-phenyl-1,2-propandiol and 1-(4-hydroxy-3-methoxy)-phenyl-2-[4-(2,3-dihydroxypropyl)-2-methoxy]-phenoxy-1,3-propandiol have been isolated for the first time. Antialgal assays show good activity for some aromatic compounds.


Phytochemistry | 2001

Potential allelochemicals from Sambucus nigra

Brigida D'Abrosca; Marina DellaGreca; Antonio Fiorentino; Pietro Monaco; Lucio Previtera; Ana M. Simonet; Armando Zarrelli

Twenty-four aromatic metabolites belonging to cyanogenins, lignans, flavonoids, and phenolic glycosides were obtained from Sambucus nigra. Structures were determined on the basis of their spectroscopic features. Two compounds have been isolated and identified as (2S)-2-O-beta-D-glucopyranosyl-2-hydroxyphenylacetic acid and benzyl 2-O-beta-D-glucopyranosyl-2,6-dihydroxybenzoate. All the compounds have been assayed on dicotyledons Lactuca sativa (lettuce) and Raphanus sativus (radish) and monocotyledon Allium cepa (onion) to test their stimulatory or inhibitory effects on seed germination and radicle elongation. Cyanogenins have a mainly inhibiting effect while lignans stimulate the growth. Some compounds show different effects on dicotyledons and monocotyledons.


Bioorganic & Medicinal Chemistry | 2009

Antioxidant efficacy of iridoid and phenylethanoid glycosides from the medicinal plant Teucrium chamaedris in cell-free systems

Severina Pacifico; Brigida D’Abrosca; Maria Teresa Pascarella; Marianna Letizia; Piera Uzzo; Vincenzo Piscopo; Antonio Fiorentino

Twelve glycosides, seven iridoids and five phenylethanoids, have been isolated from leaf and root methanolic extracts of Wall Germander (Teucrium chamaedrys), a Mediterranean species historically used as a medicinal plant. Among them, three iridoid and one phenylethanoid glycosides have been isolated and characterized for the first time. All of the structures have been elucidated on the basis of their spectral data, especially 1D and 2D NMR experiments. The antioxidative properties of pure metabolites, as well as of crude organic extracts of the plant, have been analyzed on the basis of their DPPH radical scavenging capability. The antioxidant capacity in cell-free systems of the isolated metabolites was carried out by measuring their capabilities to inhibit the synthesis of thiobarbituric acid reactive species in assay media using as oxidable substrates a vegetable fat and the pentose sugar 2-deoxyribose and to prevent oxidative damage of the hydrosoluble bovine serum albumin (BSA) protein. Phenylethanoid glycosides resulted efficacious DPPH radical, while iridoid glycosides prevent massively the 2-deoxyribose and BSA oxidations in assay media.


Phytochemistry | 2002

Phenanthrenoids from the wetland Juncus acutus

Marina DellaGreca; Antonio Fiorentino; Marina Isidori; Margherita Lavorgna; Pietro Monaco; Lucio Previtera; Armando Zarrelli

Nine 9,10-dihydrophenanthrenes, three phenanthrenes and a related pyrene have been isolated from the wetland plant Juncus acutus. The structures have been attributed by means of their spectral data and chemical correlation. 5-(1-Ethoxy-ethyl)-2-hydroxy-7-methoxy-1,8-dimethyl-9,10-dihydrophenanthrene and 5-(1-phytoxy-ethyl)-2-hydroxy-7-methoxy-1,8-dimethyl-9,10-dihydrophenanthrene, 2,7-dihydroxy-1-methyl-5-vinylphenanthrene, 2,7-dimethoxy-1,6-dimethyl-5-vinylphenanthrene and 2,7-dihydroxy-1,6-dimethylpyrene are described for the first time. Many of the compounds showed in vitro phytotoxicity against Selenastrum capricornutum, a microalga used in aquatic tests.


Journal of Chemical Ecology | 2006

Chemical Constituents of the Aquatic Plant Schoenoplectus lacustris: Evaluation of Phytotoxic Effects on the Green Alga Selenastrum capricornutum

Brigida D'Abrosca; Marina DellaGreca; Antonio Fiorentino; Marina Isidori; Pietro Monaco; Severina Pacifico

Forty-nine secondary metabolites were isolated from aqueous and alcoholic extracts of the aquatic plant Shoenoplectus lacustris. All compounds were characterized based on spectroscopic data. Eleven free and glycosylated low-molecular polyphenols, 17 cinnamic acid and dihydrocinnamic acid derivatives, 11 flavonoids, and 10 C13nor-isoprenoids were identified. The structure of the new compound, 1-benzoyl-glycerol-2-α-l-arabinopyranoside, was elucidated by 2D NMR experiments (COSY, HSQC, HMBC, NOESY). To evaluate potential phytotoxic effects, all compounds were tested on the green alga Selenastrumcapricornutum, a unicellular organism commonly used in tests of toxicity as a bioindicator of eutrophic sites. The most active compound was (−)-catechin, showing an inhibition similar to that of the algaecide CuSO4.


Phytochemistry | 2000

Antialgal ent-labdane diterpenes from Ruppia maritima

Marina DellaGreca; Antonio Fiorentino; Marina Isidori; Pietro Monaco; Armando Zarrelli

Seven ent-labdane diterpenes have been isolated from Ruppia maritima. The structures 15,16-epoxy-ent-labda-8(17),13(16),14-trien-19-al; 15,16-epoxy-ent-labda-8(17),13(16),14-trien-19-ol acetate; methyl 15,16-epoxy-12-oxo-ent-labda-8(17),13(16),14-trien-19-oate; 15,16-epoxy-ent-labd-8(17),13E-dien-15-ol and 13-oxo-15,16-bis-nor-ent-labd-8(17)-ene have been assigned to the five new compounds by spectroscopic means and chemical correlations. The phytotoxicity of the diterpenes has been assessed using the alga Selenastrum capricornutum as organism test.


Phytochemistry | 2001

Antialgal furano-diterpenes from Potamogeton natans L.

Marina DellaGreca; Antonio Fiorentino; Marina Isidori; Pietro Monaco; Fabio Temussi; Armando Zarrelli

Six furano-ent-labdanes, 19-acetoxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20-al, 15,16-epoxy-12-oxo-8(17),13(16),14-ent-labdatrien-20,19-olide, 12(S)-hydroxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20,19-olide, 10alpha,19-dihydroxy-15,16-epoxy-8(17),13(16),14-nor-ent-labdatriene, 19,20-dihydroxy-15,16-epoxy-8(17),13(16),14-ent-labdatriene, 15,16-epoxy-12-oxo-8(17),13(16),14-ent-labdatrien-19,20-olide, were isolated, together with the known potamogetonin, from the aquatic plant Potamogeton natans. Their structures were determined on the basis of their chemical and spectral data. The compounds showed in vitro phytotoxicity against Raphidocelis subcapitata, a microalga used in aquatic tests.


Phytochemistry | 1994

Progesterone bioconversion by microalgal cultures

Antonino Pollio; Gabriele Pinto; Marina Della Greca; Anna de Maio; Antonio Fiorentino; Lucio Previtera

Ten different strains of unicellular microalgae have been used in the bioconversion of progesterone. Regio and stereoselective reduction and hydroxylation of the title compound were induced. A 9,10-seco derivative was obtained in high yield by using Scenedesmus quadricauda.


Tetrahedron | 1993

Cytotoxic 9,10-dihydrophenanthrenes from Juncus effusus L.

Marina Della Greca; Antonio Fiorentino; Lorenzo Mangoni; Antonio Molinaro; Pietro Monaco; Lucio Previtera

Abstract Nine 9,10-dihydrophenanthrenes, seven of them described for the first time, have been isolated in a further investigation of Juncus effusus. The structures have been defined on the basis of the spectral properties of the compounds. All the dehydrophenanthrene metabolites present in the plant have been tested for their cytotoxic properties and many of them have been found to have a good in vitro activity.


Journal of Natural Products | 2010

Spectroscopic characterization and antiproliferative activity on HepG2 human hepatoblastoma cells of flavonoid C-glycosides from Petrorhagia velutina.

S. Pacifico; M. Scognamiglio; Brigida D'Abrosca; S. Piccolella; N. Tsafantakis; M. Gallicchio; A. Ricci; Antonio Fiorentino

Eight flavonoid C-glycosides, including three new analogues, have been isolated from leaf and root methanolic extracts of Petrorhagia velutina, a Mediterranean herbaceous plant. The antiproliferative activity against human hepatoblastoma cancer cell line HepG2 has been analyzed by the MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) test. Isoorientin (4) significantly reduces the proliferation of HepG2 cells as determined by the complete conversion of the tetrazolium probe into formazan after 48 h of exposure.

Collaboration


Dive into the Antonio Fiorentino's collaboration.

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Pietro Monaco

Seconda Università degli Studi di Napoli

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Severina Pacifico

Seconda Università degli Studi di Napoli

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Brigida D'Abrosca

Seconda Università degli Studi di Napoli

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Monica Scognamiglio

Seconda Università degli Studi di Napoli

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Lucio Previtera

University of Naples Federico II

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Marina DellaGreca

University of Naples Federico II

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Brigida D’Abrosca

Seconda Università degli Studi di Napoli

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Armando Zarrelli

University of Naples Federico II

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Assunta Esposito

Seconda Università degli Studi di Napoli

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Marina Isidori

Seconda Università degli Studi di Napoli

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